| Pressure stability of proteins. JL Silva, G Weber Annu. Rev. Phys. Chem 44 (89), 113, 1993 | 644 | 1993 |
| Pressure provides new insights into protein folding, dynamics and structure JL Silva, D Foguel, CA Royer Trends in biochemical sciences 26 (10), 612-618, 2001 | 462 | 2001 |
| Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer APDA Bom, LP Rangel, DCF Costa, GAP de Oliveira, D Sanches, ... Journal of Biological Chemistry 287 (33), 28152-28162, 2012 | 322 | 2012 |
| DNA converts cellular prion protein into the β-sheet conformation and inhibits prion peptide aggregation Y Cordeiro, F Machado, L Juliano, MA Juliano, RR Brentani, D Foguel, ... Journal of Biological Chemistry 276 (52), 49400-49409, 2001 | 258 | 2001 |
| Pressure dissociation and conformational drift of the. beta. dimer of tryptophan synthase JL Silva, EW Miles, G Weber Biochemistry 25 (19), 5780-5786, 1986 | 247 | 1986 |
| Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion. SN Moreno, J Silva, AE Vercesi, R Docampo The Journal of experimental medicine 180 (4), 1535-1540, 1994 | 244 | 1994 |
| The preaggregated state of an amyloidogenic protein: hydrostatic pressure converts native transthyretin into the amyloidogenic state AD Ferrao-Gonzales, SO Souto, JL Silva, D Foguel Proceedings of the National Academy of Sciences 97 (12), 6445-6450, 2000 | 234 | 2000 |
| Dissociation of amyloid fibrils of α-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities D Foguel, MC Suarez, AD Ferrão-Gonzales, TCR Porto, L Palmieri, ... Proceedings of the National Academy of Sciences 100 (17), 9831-9836, 2003 | 226 | 2003 |
| High-pressure chemical biology and biotechnology JL Silva, AC Oliveira, TCRG Vieira, GAP de Oliveira, MC Suarez, ... Chemical reviews 114 (14), 7239-7267, 2014 | 225 | 2014 |
| Prion-like aggregation of mutant p53 in cancer JL Silva, CVDM Gallo, DCF Costa, LP Rangel Trends in biochemical sciences 39 (6), 260-267, 2014 | 221 | 2014 |
| Fibrillar aggregates of the tumor suppressor p53 core domain D Ishimaru, LR Andrade, LSP Teixeira, PA Quesado, LM Maiolino, ... Biochemistry 42 (30), 9022-9027, 2003 | 217 | 2003 |
| Dissociation of a native dimer to a molten globule monomer: effects of pressure and dilution on the association equilibrium of arc repressor JL Silva, CF Silveira, A Correia Jr, L Pontes Journal of molecular biology 223 (2), 545-555, 1992 | 181 | 1992 |
| The use of hydrostatic pressure as a tool to study viruses and other macromolecular assemblages JL Silva, D Foguel, AT Da Poian, PE Prevelige Current Opinion in Structural Biology 6 (2), 166-175, 1996 | 173 | 1996 |
| Effects of hydrostatic pressure on a membrane-enveloped virus: high immunogenicity of the pressure-inactivated virus JL Silva, P Luan, M Glaser, EW Voss, G Weber Journal of virology 66 (4), 2111-2117, 1992 | 142 | 1992 |
| Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors CB Levy, AC Stumbo, APDA Bom, EA Portari, Y Carneiro, JL Silva, ... The international journal of biochemistry & cell biology 43 (1), 60-64, 2011 | 137 | 2011 |
| Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins JL Silva, TCRG Vieira, MPB Gomes, APA Bom, LMTR Lima, MS Freitas, ... Accounts of chemical research 43 (2), 271-279, 2010 | 135 | 2010 |
| The aggregation of mutant p53 produces prion-like properties in cancer LP Rangel, DCF Costa, TCRG Vieira, JL Silva Prion 8 (1), 75-84, 2014 | 127 | 2014 |
| Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease GAP de Oliveira, JL Silva Communications biology 2 (1), 374, 2019 | 126 | 2019 |
| Targeting the prion-like aggregation of mutant p53 to combat cancer JL Silva, EA Cino, IN Soares, VF Ferreira, G AP de Oliveira Accounts of chemical research 51 (1), 181-190, 2018 | 124 | 2018 |
| Intriguing nucleic-acid-binding features of mammalian prion protein JL Silva, LMTR Lima, D Foguel, Y Cordeiro Trends in biochemical sciences 33 (3), 132-140, 2008 | 122 | 2008 |
Debora FoguelProfessor Titular, Universidade Federal do Rio de JaneiroVerified email at bioqmed.ufrj.br
