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David Gallego-Ortega
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Myeloid-derived suppressor cells as a therapeutic target for cancer
AMK Law, F Valdes-Mora, D Gallego-Ortega
Cells 9 (3), 561, 2020
4122020
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ...
Science translational medicine 9 (384), eaai8504, 2017
2602017
Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study
AR de Molina, J Sarmentero-Estrada, C Belda-Iniesta, M Tarón, ...
The lancet oncology 8 (10), 889-897, 2007
1862007
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis
M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ...
Nature communications 13 (1), 4587, 2022
1272022
The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy
AMK Law, E Lim, CJ Ormandy, D Gallego-Ortega
Endocrine-related cancer 24 (4), R123, 2017
1242017
Differential role of human choline kinase α and β enzymes in lipid metabolism: implications in cancer onset and treatment
D Gallego-Ortega, A Ramirez de Molina, MA Ramos, F Valdes-Mora, ...
PloS one 4 (11), e7819, 2009
1222009
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ...
Development 140 (7), 1397-1401, 2013
1212013
Droplet-based single cell RNAseq tools: a practical guide
R Salomon, D Kaczorowski, F Valdes-Mora, RE Nordon, A Neild, ...
Lab on a Chip 19 (10), 1706-1727, 2019
1192019
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer
M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ...
PLoS biology 10 (12), e1001461, 2012
1052012
TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer
F Valdés-Mora, T Gomez del Pulgar, E Bandrés, P Cejas, ...
Annals of surgical oncology 16, 78-87, 2009
1052009
Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway
DR Croucher, F Hochgräfe, L Zhang, L Liu, RJ Lyons, D Rickwood, ...
Cancer research 73 (6), 1969-1980, 2013
1042013
Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy
AR de Molina, D Gallego-Ortega, J Sarmentero-Estrada, D Lagares, ...
The international journal of biochemistry & cell biology 40 (9), 1753-1763, 2008
1042008
Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesis
A Ramírez de Molina, D Gallego-Ortega, J Sarmentero, M Bañez-Coronel, ...
Cancer research 65 (13), 5647-5653, 2005
1042005
A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts
M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ...
Cell reports 21 (1), 274-288, 2017
972017
Acetylated histone variant H2A. Z is involved in the activation of neo-enhancers in prostate cancer
F Valdés-Mora, CM Gould, Y Colino-Sanguino, W Qu, JZ Song, KM Taylor, ...
Nature Communications 8 (1), 1346, 2017
912017
Regulation of Akt (ser473) phosphorylation by choline kinase in breast carcinoma cells
BT Chua, D Gallego-Ortega, AR de Molina, A Ullrich, JC Lacal, ...
Molecular Cancer 8, 1-12, 2009
912009
Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization
JU Mayer, KL Hilligan, JS Chandler, DA Eccles, SI Old, RG Domingues, ...
Nature immunology 22 (12), 1538-1550, 2021
902021
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib
AIJ Young, AMK Law, L Castillo, S Chong, HD Cullen, M Koehler, ...
Breast Cancer Research 18, 1-15, 2016
882016
Single-cell transcriptomics in cancer immunobiology: the future of precision oncology
F Valdes-Mora, K Handler, AMK Law, R Salomon, SR Oakes, ...
Frontiers in immunology 9, 2582, 2018
852018
ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells
D Gallego-Ortega, A Ledger, DL Roden, AMK Law, A Magenau, ...
PLoS biology 13 (12), e1002330, 2015
812015
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