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Dr. R. Ajay Guru
Dr. R. Ajay Guru
Scientist, Saveetha Institute of Medical and Technical Science
Verified email at saveetha.com
Title
Cited by
Cited by
Year
Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds
A Guru, PK Issac, M Velayutham, NT Saraswathi, A Arshad, J Arockiaraj
Molecular Biology Reports 48 (1), 743-761, 2021
902021
Oxidative stress induced antioxidant and neurotoxicity demonstrated in vivo zebrafish embryo or larval model and their normalization due to morin showing therapeutic implications
PK Issac, A Guru, M Velayutham, R Pachaiappan, MV Arasu, NA Al-Dhabi, ...
Life sciences 283, 119864, 2021
882021
Intracellular ROS scavenging and antioxidant regulation of WL15 from cysteine and glycine-rich protein 2 demonstrated in zebrafish in vivo model
A Guru, C Lite, AJ Freddy, PK Issac, M Pasupuleti, NT Saraswathi, ...
Developmental & Comparative Immunology 114, 103863, 2021
812021
Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety‐like neurobehavioral response associated with oxidative stress and …
C Lite, A Guru, M Juliet, J Arockiaraj
Environmental Toxicology 37 (8), 1988-2004, 2022
592022
Amelioration of acrylamide induced neurotoxicity by benzo [b] thiophene analogs via glutathione redox dynamics in zebrafish larvae
B Haridevamuthu, T Manjunathan, A Guru, CRW Alphonse, S Boopathi, ...
Brain Research 1788, 147941, 2022
582022
Hydroxyl containing benzo [b] thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle
B Haridevamuthu, T Manjunathan, A Guru, RS Kumar, R Rajagopal, ...
Life Sciences 298, 120507, 2022
522022
6‐Gingerol and semisynthetic 6‐Gingerdione counteract oxidative stress induced by ROS in zebrafish
T Manjunathan, A Guru, J Arokiaraj, P Gopinath
Chemistry & Biodiversity 18 (12), e2100650, 2021
502021
Neuroprotective effect of Biochanin a against Bisphenol A-induced prenatal neurotoxicity in zebrafish by modulating oxidative stress and locomotory defects
B Haridevamuthu, A Guru, R Murugan, G Sudhakaran, R Pachaiappan, ...
Neuroscience Letters 790, 136889, 2022
472022
Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of …
G Sudhakaran, P Prathap, A Guru, B Haridevamuthu, R Murugan, ...
Molecular and cellular biochemistry 477 (10), 2387-2401, 2022
472022
Anti‐inflammatory role demonstrated both in vitro and in vivo models using nonsteroidal tetranortriterpenoid, Nimbin (N1) and its analogs (N2 and N3) that alleviate the …
G Sudhakaran, P Prathap, A Guru, R Rajesh, S Sathish, T Madhavan, ...
Cell Biology International 46 (5), 771-791, 2022
452022
Tryptophan-tagged peptide from serine threonine-protein kinase of Channa striatus improves antioxidant defence in L6 myotubes and attenuates caspase 3 …
PK Issac, C Lite, A Guru, M Velayutham, G Kuppusamy, NT Saraswathi, ...
Fish physiology and biochemistry 47, 293-311, 2021
442021
Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism
PK Issac, A Guru, SS Chandrakumar, C Lite, NT Saraswathi, MV Arasu, ...
Molecular Biology Reports 47 (9), 6727-6740, 2020
442020
Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach
R Murugan, R Rajesh, B Seenivasan, B Haridevamuthu, G Sudhakaran, ...
Microbial Pathogenesis 172, 105778, 2022
432022
Lipid-lowering and antioxidant activity of RF13 peptide from vacuolar protein sorting-associated protein 26B (VPS26B) by modulating lipid metabolism and oxidative stress in HFD …
A Guru, M Velayutham, J Arockiaraj
International Journal of Peptide Research and Therapeutics 28 (2), 74, 2022
432022
Insulin signaling pathway assessment by enhancing antioxidant activity due to morin using in vitro rat skeletal muscle L6 myotubes cells
PK Issac, R Karan, A Guru, R Pachaiappan, MV Arasu, NA Al-Dhabi, ...
Molecular Biology Reports 48, 5857-5872, 2021
432021
GR15 peptide of S-adenosylmethionine synthase (SAMe) from Arthrospira platensis demonstrated antioxidant mechanism against H2O2 induced oxidative stress in in-vitro MDCK cells …
M Velayutham, A Guru, MV Arasu, NA Al-Dhabi, KC Choi, P Elumalai, ...
Journal of Biotechnology 342, 79-91, 2021
412021
Neuroprotective and antioxidant capability of RW20 peptide from histone acetyltransferases caused by oxidative stress-induced neurotoxicity in in vivo zebrafish larval model
N Prabha, A Guru, R Harikrishnan, MK Gatasheh, AA Hatamleh, A Juliet, ...
Journal of King Saud University-Science 34 (3), 101861, 2022
402022
NV14 from serine O‐acetyltransferase of cyanobacteria influences the antioxidant enzymes in vitro cells, gene expression against H2O2 and other responses in …
M Velayutham, B Ojha, PK Issac, C Lite, A Guru, M Pasupuleti, MV Arasu, ...
Cell Biology International 45 (11), 2331-2346, 2021
392021
Deteriorating insulin resistance due to WL15 peptide from cysteine and glycine‐rich protein 2 in high glucose‐induced rat skeletal muscle L6 cells
A Guru, PK Issac, NT Saraswathi, VD Seshadri, GA Gabr, J Arockiaraj
Cell Biology International 45 (8), 1698-1709, 2021
372021
Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection
A Guru, G Sudhakaran, M Velayutham, R Murugan, R Pachaiappan, ...
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2022
352022
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