α-Ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain AU Amaral, G Leipnitz, CG Fernandes, B Seminotti, PF Schuck, M Wajner Brain research 1324, 75-84, 2010 | 116 | 2010 |
In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain G Leipnitz, C Schumacher, KB Dalcin, K Scussiato, A Solano, C Funchal, ... Neurochemistry international 50 (1), 83-94, 2007 | 105 | 2007 |
Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro CG Da Silva, CAJ Ribeiro, G Leipnitz, CS Dutra-Filho, ÂTS Wyse, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1586 (1), 81-91, 2002 | 100 | 2002 |
Evidences that maternal swimming exercise improves antioxidant defenses and induces mitochondrial biogenesis in the brain of young Wistar rats TB Marcelino, A Longoni, KY Kudo, V Stone, A Rech, AM De Assis, ... Neuroscience 246, 28-39, 2013 | 85 | 2013 |
Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury V Glaser, G Leipnitz, MR Straliotto, J Oliveira, VV dos Santos, ... Neurotoxicology 31 (5), 454-460, 2010 | 73 | 2010 |
Induction of oxidative stress by L‐2‐hydroxyglutaric acid in rat brain A Latini, K Scussiato, R Borba Rosa, G Leipnitz, S Llesuy, A Belló‐Klein, ... Journal of neuroscience research 74 (1), 103-110, 2003 | 73 | 2003 |
Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I … G Leipnitz, AW Mohsen, A Karunanidhi, B Seminotti, VY Roginskaya, ... Scientific reports 8 (1), 1165, 2018 | 70 | 2018 |
Experimental evidence that phenylalanine provokes oxidative stress in hippocampus and cerebral cortex of developing rats CG Fernandes, G Leipnitz, B Seminotti, AU Amaral, Â Zanatta, CR Vargas, ... Cellular and molecular neurobiology 30, 317-326, 2010 | 70 | 2010 |
Experimental evidence that methylmalonic acid provokes oxidative damage and compromises antioxidant defenses in nerve terminal and striatum of young rats CG Fernandes, CG Borges, B Seminotti, AU Amaral, LA Knebel, P Eichler, ... Cellular and molecular neurobiology 31, 775-785, 2011 | 68 | 2011 |
Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats G Leipnitz, C Schumacher, K Scussiato, KB Dalcin, CMD Wannmacher, ... International Journal of Developmental Neuroscience 23 (8), 695-701, 2005 | 65 | 2005 |
3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats A Latini, M Rodriguez, RB Rosa, K Scussiato, G Leipnitz, DR De Assis, ... Neuroscience 135 (1), 111-120, 2005 | 62 | 2005 |
Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers B Seminotti, G Leipnitz, A Karunanidhi, C Kochersperger, VY Roginskaya, ... Human molecular genetics 28 (6), 928-941, 2019 | 61 | 2019 |
Antioxidant properties of mesenchymal stem cells against oxidative stress in a murine model of colitis F da Costa Gonçalves, M Grings, NS Nunes, FO Pinto, TNA Garcez, ... Biotechnology letters 39, 613-622, 2017 | 61 | 2017 |
Promotion of oxidative stress by 3‐hydroxyglutaric acid in rat striatum A Latini, K Scussiato, G Leipnitz, CS Dutra‐Filho, M Wajner Journal of Inherited Metabolic Disease: Official Journal of the Society for …, 2005 | 61 | 2005 |
Inhibition of creatine kinase activity from rat cerebral cortex by D-2-hydroxyglutaric acid in vitro CG Da Silva, ARF Bueno, PF Schuck, G Leipnitz, CAJ Ribeiro, RB Rosa, ... Neurochemistry international 44 (1), 45-52, 2004 | 58 | 2004 |
Bezafibrate prevents mitochondrial dysfunction, antioxidant system disturbance, glial reactivity and neuronal damage induced by sulfite administration in striatum of rats … M Grings, AP Moura, B Parmeggiani, JT Pletsch, GMF Cardoso, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (9 …, 2017 | 55 | 2017 |
Inhibition of Creatine Kinase Activity in Vitro by Ethylmalonic Acid in Cerebral Cortex of Young Rats PF Schuck, G Leipnitz, CAJ Ribeiro, KB Dalcin, DR Assis, AG Barschak, ... Neurochemical research 27, 1633-1639, 2002 | 54 | 2002 |
Physical exercise during pregnancy prevents cognitive impairment induced by amyloid-β in adult offspring rats CP Klein, JB Hoppe, AB Saccomori, BG Dos Santos, JP Sagini, ... Molecular neurobiology 56, 2022-2038, 2019 | 53 | 2019 |
The disturbance of antioxidant/oxidant balance in fish experimentally infected by Aeromonas caviae: relationship with disease pathophysiology MD Baldissera, CF Souza, B Parmeggiani, G Leipnitz, CM Verdi, ... Microbial pathogenesis 122, 53-57, 2018 | 48 | 2018 |
Oxidative stress, disrupted energy metabolism, and altered signaling pathways in glutaryl-CoA dehydrogenase knockout mice: potential implications of quinolinic acid toxicity in … B Seminotti, AU Amaral, RT Ribeiro, MDN Rodrigues, AL Colín-González, ... Molecular neurobiology 53, 6459-6475, 2016 | 45 | 2016 |