NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression MA Huber, N Azoitei, B Baumann, S Grünert, A Sommer, H Pehamberger, ... The Journal of clinical investigation 114 (4), 569-581, 2004 | 1350 | 2004 |
PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation N Azoitei, A Becher, K Steinestel, A Rouhi, K Diepold, F Genze, T Simmet, ... Molecular cancer 15, 1-15, 2016 | 326 | 2016 |
Variant classification in precision oncology J Leichsenring, P Horak, S Kreutzfeldt, C Heining, P Christopoulos, ... International Journal of Cancer 145 (11), 2996-3010, 2019 | 109 | 2019 |
ATM deficiency generating genomic instability sensitizes pancreatic ductal adenocarcinoma cells to therapy-induced DNA damage L Perkhofer, A Schmitt, MC Romero Carrasco, M Ihle, S Hampp, ... Cancer research 77 (20), 5576-5590, 2017 | 109 | 2017 |
Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix … J Wenk, J Schuller, C Hinrichs, T Syrovets, N Azoitei, M Podda, ... Journal of Biological Chemistry 279 (44), 45634-45642, 2004 | 96 | 2004 |
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours N Azoitei, GV Pusapati, A Kleger, P Möller, R Küfer, F Genze, M Wagner, ... Gut 59 (10), 1316-1330, 2010 | 89 | 2010 |
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells M Breunig, J Merkle, M Wagner, MK Melzer, TFE Barth, T Engleitner, ... Cell Stem Cell 28 (6), 1105-1124. e19, 2021 | 85 | 2021 |
Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33 N Azoitei, CM Hoffmann, JM Ellegast, CR Ball, K Obermayer, U Gößele, ... Journal of Experimental Medicine 209 (4), 697-711, 2012 | 78 | 2012 |
HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization N Azoitei, K Diepold, C Brunner, A Rouhi, F Genze, A Becher, H Kestler, ... Cancer research 74 (23), 7125-7136, 2014 | 76 | 2014 |
Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer J Gout, L Perkhofer, M Morawe, F Arnold, M Ihle, S Biber, S Lange, ... Gut 70 (4), 743-760, 2021 | 67 | 2021 |
Thirty-eight-negative kinase 1 (TNK1) facilitates TNFα-induced apoptosis by blocking NF-κB activation N Azoitei, A Brey, T Busch, S Fulda, G Adler, T Seufferlein Oncogene 26 (45), 6536-6545, 2007 | 55 | 2007 |
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure M Armacki, AK Trugenberger, AK Ellwanger, T Eiseler, C Schwerdt, ... The Journal of clinical investigation 128 (11), 5056-5072, 2018 | 51 | 2018 |
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation N Azoitei, A Kleger, N Schoo, DR Thal, C Brunner, GV Pusapati, ... Neuro-oncology 13 (7), 710-724, 2011 | 51 | 2011 |
Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone S Bekeschus, M Lippert, K Diepold, G Chiosis, T Seufferlein, N Azoitei Scientific reports 9 (1), 4112, 2019 | 49 | 2019 |
Activation of the IκB kinase complex is sufficient for neuronal differentiation of PC12 cells N Azoitei, T Wirth, B Baumann Journal of neurochemistry 93 (6), 1487-1501, 2005 | 35 | 2005 |
Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells M Wilkat, H Bast, R Drees, J Dünser, A Mahr, N Azoitei, R Marienfeld, ... International journal of cancer 147 (1), 202-217, 2020 | 31 | 2020 |
Requirement for YAP1 signaling in myxoid liposarcoma M Trautmann, YY Cheng, P Jensen, N Azoitei, I Brunner, J Hüllein, ... EMBO molecular medicine 11 (5), e9889, 2019 | 28 | 2019 |
Protein kinase D2: a versatile player in cancer biology N Azoitei, M Cobbaut, A Becher, J Van Lint, T Seufferlein Oncogene 37 (10), 1263-1278, 2018 | 26 | 2018 |
STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1α/VEGF signaling pathway Y Liu, K Steinestel, A Rouhi, M Armacki, K Diepold, G Chiosis, T Simmet, ... Oncotarget 8 (44), 77474, 2017 | 22 | 2017 |
Telomerase and pluripotency factors jointly regulate stemness in pancreatic cancer stem cells K Walter, E Rodriguez-Aznar, MSV Ferreira, PO Frappart, T Dittrich, ... Cancers 13 (13), 3145, 2021 | 21 | 2021 |