| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 12 (1), 1-222, 2016 | 14170* | 2016 |
| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 316 | 2016 |
| The apicomplexan glideosome and adhesins – Structures and function LE Boucher, J Bosch Journal of Structural Biology, 2015 | 128 | 2015 |
| Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite J Bosch, CA Buscaglia, B Krumm, BP Ingason, R Lucas, C Roach, ... Proceedings of the National Academy of Sciences 104 (17), 7015-7020, 2007 | 109 | 2007 |
| Structure of the MTIP–MyoA complex, a key component of the malaria parasite invasion motor J Bosch, S Turley, TM Daly, SM Bogh, ML Villasmil, C Roach, N Zhou, ... Proceedings of the National Academy of Sciences 103 (13), 4852-4857, 2006 | 89 | 2006 |
| Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase J Bosch, MA Robien, C Mehlin, E Boni, A Riechers, FS Buckner, ... Journal of medicinal chemistry 49 (20), 5939-5946, 2006 | 78 | 2006 |
| The closed MTIP-myosin A-tail complex from the malaria parasite invasion machinery J Bosch, S Turley, CM Roach, TM Daly, LW Bergman, WGJ Hol Journal of molecular biology 372 (1), 77-88, 2007 | 68 | 2007 |
| Microfluidic assessment of red blood cell mediated microvascular occlusion Y Man, E Kucukal, R An, QD Watson, J Bosch, PA Zimmerman, JA Little, ... Lab on a Chip 20 (12), 2086-2099, 2020 | 67 | 2020 |
| Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction AUP Hain, RR Weltzer, H Hammond, B Jayabalasingham, RR Dinglasan, ... Journal of structural biology 180 (3), 551-562, 2012 | 62 | 2012 |
| Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum … JB AU Hain, D Bartee, NG Sanders, AS Miller,DJ Sullivan, J Levitskaya, CF Meyers Journal of Medicinal Chemistry 57 (11), 4521–4531, 2014 | 56 | 2014 |
| Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin RG Saraiva, CR Huitt-Roehl, A Tripathi, YQ Cheng, J Bosch, ... Scientific reports 8 (1), 6176, 2018 | 52 | 2018 |
| Crystal structure of glyceraldehyde‐3‐phosphate dehydrogenase from Plasmodium falciparum at 2.25 Å resolution reveals intriguing extra electron density in the active site MA Robien, J Bosch, FS Buckner, WCE Van Voorhis, EA Worthey, P Myler, ... Proteins: Structure, Function, and Bioinformatics 62 (3), 570-577, 2006 | 52 | 2006 |
| Autophagy in Plasmodium, a multifunctional pathway? AUP Hain, J Bosch Computational and structural biotechnology journal 8 (11), e201308002, 2013 | 46 | 2013 |
| DXP Synthase‐Catalyzed C N Bond Formation: Nitroso Substrate Specificity Studies Guide Selective Inhibitor Design F Morris, R Vierling, L Boucher, J Bosch, CL Freel Meyers ChemBioChem 14 (11), 1309-1315, 2013 | 46 | 2013 |
| Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium CLMJ Verlinde, E Fan, S Shibata, Z Zhang, Z Sun, W Deng, J Ross, J Kim, ... Current topics in medicinal chemistry 9 (18), 1678-1687, 2009 | 45 | 2009 |
| Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems? B Jayabalasingham, C Voss, K Ehrenman, JD Romano, ME Smith, ... Autophagy 10 (2), 269-284, 2014 | 41 | 2014 |
| Structural genomics of pathogenic protozoa: an overview E Fan, D Baker, S Fields, MH Gelb, FS Buckner, WC Van Voorhis, ... Structural Proteomics: High-Throughput Methods, 497-513, 2008 | 41 | 2008 |
| High-throughput activity assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain M Dasovich, J Zhuo, JA Goodman, A Thomas, RL McPherson, ... ACS chemical biology 17 (1), 17-23, 2021 | 40 | 2021 |
| Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum J Bosch, MH Paige, AB Vaidya, LW Bergman, WGJ Hol Journal of structural biology 178 (1), 61-73, 2012 | 38 | 2012 |
| Identification of biochemically distinct properties of the small ubiquitin-related modifier (SUMO) conjugation pathway in Plasmodium falciparum K Reiter, D Mukhopadhyay, H Zhang, LE Boucher, N Kumar, J Bosch, ... Journal of Biological Chemistry 288 (39), 27724-27736, 2013 | 35 | 2013 |
Lauren E. BoucherAbbVieVerified email at abbvie.com
