Human chimeric antigen receptor macrophages for cancer immunotherapy M Klichinsky, M Ruella, O Shestova, XM Lu, A Best, M Zeeman, ... Nature biotechnology 38 (8), 947-953, 2020 | 1133 | 2020 |
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma AP Weng, JM Millholland, Y Yashiro-Ohtani, ML Arcangeli, A Lau, C Wai, ... Genes & development 20 (15), 2096-2109, 2006 | 1104 | 2006 |
Notch directly regulates Gata3 expression during T helper 2 cell differentiation TC Fang, Y Yashiro-Ohtani, C Del Bianco, DM Knoblock, SC Blacklow, ... Immunity 27 (1), 100-110, 2007 | 486 | 2007 |
A critical role for TCF-1 in T-lineage specification and differentiation BN Weber, AWS Chi, A Chavez, Y Yashiro-Ohtani, Q Yang, O Shestova, ... Nature 476 (7358), 63-68, 2011 | 475 | 2011 |
The requirement for Notch signaling at the β-selection checkpoint in vivo is absolute and independent of the pre–T cell receptor I Maillard, LL Tu, A Sambandam, Y Yashiro-Ohtani, J Millholland, ... Journal of Experimental Medicine 203 (10), 2239-2245, 2006 | 363* | 2006 |
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1 BJ Wouters, MA Jorda, K Keeshan, I Louwers, ... Blood, The Journal of the American Society of Hematology 110 (10), 3706-3714, 2007 | 251 | 2007 |
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A Y Yashiro-Ohtani, Y He, T Ohtani, ME Jones, O Shestova, L Xu, TC Fang, ... Genes & development 23 (14), 1665-1676, 2009 | 224 | 2009 |
Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts Y Yashiro-Ohtani, XY Zhou, K Toyo-Oka, XG Tai, CS Park, T Hamaoka, ... the Journal of Immunology 164 (3), 1251-1259, 2000 | 224 | 2000 |
The expression of Sox17 identifies and regulates haemogenic endothelium RL Clarke, AD Yzaguirre, Y Yashiro-Ohtani, A Bondue, C Blanpain, ... Nature cell biology 15 (5), 502-510, 2013 | 193 | 2013 |
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia Y Yashiro-Ohtani, H Wang, C Zang, KL Arnett, W Bailis, Y Ho, B Knoechel, ... Proceedings of the National Academy of Sciences 111 (46), E4946-E4953, 2014 | 191 | 2014 |
Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals W Bailis, Y Yashiro-Ohtani, TC Fang, RD Hatton, CT Weaver, D Artis, ... Immunity 39 (1), 148-159, 2013 | 159 | 2013 |
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network S Ohashi, M Natsuizaka, Y Yashiro–Ohtani, RA Kalman, M Nakagawa, ... Gastroenterology 139 (6), 2113-2123, 2010 | 153 | 2010 |
The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3 P Gao, XY Zhou, Y Yashiro-Ohtani, YF Yang, N Sugimoto, S Ono, ... Journal of Leucocyte Biology 73 (2), 273-280, 2003 | 152 | 2003 |
Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1 R Fragoso, T Mao, S Wang, S Schaffert, X Gong, S Yue, R Luong, H Min, ... Public Library of Science 8 (8), e1002855, 2012 | 139 | 2012 |
Active Notch1 confers a transformed phenotype to primary human melanocytes CC Pinnix, JT Lee, ZJ Liu, R McDaid, K Balint, LJ Beverly, PA Brafford, ... Cancer research 69 (13), 5312-5320, 2009 | 136 | 2009 |
T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1 ME De Obaldia, JJ Bell, X Wang, C Harly, Y Yashiro-Ohtani, JH DeLong, ... Nature immunology 14 (12), 1277-1284, 2013 | 118 | 2013 |
A role for CD9 molecules in T cell activation. XG Tai, Y Yashiro, R Abe, K Toyooka, CR Wood, J Morris, A Long, S Ono, ... The Journal of experimental medicine 184 (2), 753-758, 1996 | 112 | 1996 |
Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway T Nakanishi, A Hayashi, J Kunisawa, Y Tsutsumi, K Tanaka, ... European Journal of Immunology 30 (6), 1740-1747, 2000 | 92 | 2000 |
Molecular mechanisms underlying differential contribution of CD28 versus non-CD28 costimulatory molecules to IL-2 promoter activation XY Zhou, Y Yashiro-Ohtani, M Nakahira, WR Park, R Abe, T Hamaoka, ... The Journal of Immunology 168 (8), 3847-3854, 2002 | 77 | 2002 |
A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co‐stimulatory molecules Y Yashiro, XG Tai, K Toyo‐oka, CS Park, R Abe, T Hamaoka, ... European journal of immunology 28 (3), 926-935, 1998 | 75 | 1998 |