| Amiloride and its analogs as tools in the study of ion transport. TR Kleyman, EJ Cragoe Jr The Journal of membrane biology 105 (1), 1-21, 1988 | 1446 | 1988 |
| Epithelial sodium channels are activated by furin-dependent proteolysis RP Hughey, JB Bruns, CL Kinlough, KL Harkleroad, Q Tong, ... Journal of Biological Chemistry 279 (18), 18111-18114, 2004 | 444 | 2004 |
| ENaC at the cutting edge: regulation of epithelial sodium channels by proteases TR Kleyman, MD Carattino, RP Hughey Journal of Biological Chemistry 284 (31), 20447-20451, 2009 | 363 | 2009 |
| Epithelial Na+ channels are fully activated by furin-and prostasin-dependent release of an inhibitory peptide from the γ-subunit JB Bruns, MD Carattino, S Sheng, AB Maarouf, OA Weisz, JM Pilewski, ... Journal of Biological Chemistry 282 (9), 6153-6160, 2007 | 360 | 2007 |
| Flow-dependent K+ secretion in the cortical collecting duct is mediated by a maxi-K channel CB Woda, A Bragin, TR Kleyman, LM Satlin American Journal of Physiology-Renal Physiology 280 (5), F786-F793, 2001 | 316 | 2001 |
| Maturation of the epithelial Na+ channel involves proteolytic processing of the α-and γ-subunits RP Hughey, GM Mueller, JB Bruns, CL Kinlough, PA Poland, ... Journal of Biological Chemistry 278 (39), 37073-37082, 2003 | 313 | 2003 |
| Subunit stoichiometry of the epithelial sodium channel F Kosari, S Sheng, J Li, DOD Mak, JK Foskett, TR Kleyman Journal of Biological Chemistry 273 (22), 13469-13474, 1998 | 277 | 1998 |
| Epithelial Na+ channels are regulated by flow LM Satlin, S Sheng, CB Woda, TR Kleyman American Journal of Physiology-Renal Physiology 280 (6), F1010-F1018, 2001 | 246 | 2001 |
| Aldosterone alters the open probability of amiloride-blockable sodium channels in A6 epithelia AE Kemendy, TR Kleyman, DC Eaton American Journal of Physiology-Cell Physiology 263 (4), C825-C837, 1992 | 234 | 1992 |
| Plasmin activates epithelial Na+ channels by cleaving the γ subunit CJ Passero, GM Mueller, H Rondon-Berrios, SP Tofovic, RP Hughey, ... Journal of Biological Chemistry 283 (52), 36586-36591, 2008 | 219 | 2008 |
| Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition S Sheng, MD Carattino, JB Bruns, RP Hughey, TR Kleyman American Journal of Physiology-Renal Physiology 290 (6), F1488-F1496, 2006 | 206 | 2006 |
| Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels SB Goldfarb, OB Kashlan, JN Watkins, L Suaud, W Yan, TR Kleyman, ... Proceedings of the National Academy of Sciences 103 (15), 5817-5822, 2006 | 193 | 2006 |
| Distinct pools of epithelial sodium channels are expressed at the plasma membrane RP Hughey, JB Bruns, CL Kinlough, TR Kleyman Journal of Biological Chemistry 279 (47), 48491-48494, 2004 | 190 | 2004 |
| Epithelial Na+ channels are activated by laminar shear stress MD Carattino, S Sheng, TR Kleyman Journal of Biological Chemistry 279 (6), 4120-4126, 2004 | 186 | 2004 |
| ENaC structure and function in the wake of a resolved structure of a family member OB Kashlan, TR Kleyman American Journal of Physiology-Renal Physiology 301 (4), F684-F696, 2011 | 183 | 2011 |
| The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its α subunit MD Carattino, S Sheng, JB Bruns, JM Pilewski, RP Hughey, TR Kleyman Journal of Biological Chemistry 281 (27), 18901-18907, 2006 | 182 | 2006 |
| Hypertension: do inflammation and immunity hold the key to solving this epidemic? MS Madhur, F Elijovich, MR Alexander, A Pitzer, J Ishimwe, ... Circulation research 128 (7), 908-933, 2021 | 168 | 2021 |
| Trimethoprim-induced hyperkalemia in a patient with AIDS MJ Choi, PC Fernandez, A Patnaik, B Coupaye-Gerard, D D'andrea, ... New england journal of medicine 328 (10), 703-706, 1993 | 164 | 1993 |
| Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells MD Carattino, RS Edinger, HJ Grieser, R Wise, D Neumann, U Schlattner, ... Journal of Biological Chemistry 280 (18), 17608-17616, 2005 | 160 | 2005 |
| Role of epithelial sodium channels and their regulators in hypertension R Soundararajan, D Pearce, RP Hughey, TR Kleyman Journal of Biological Chemistry 285 (40), 30363-30369, 2010 | 140 | 2010 |
Marcelo CarattinoUniversity of PittsburghVerified email at pitt.edu