| The airway epithelium: structural and functional properties in health and disease DA Knight, ST Holgate Respirology 8 (4), 432-446, 2003 | 811 | 2003 |
| Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma SS An, TR Bai, JHT Bates, JL Black, RH Brown, V Brusasco, P Chitano, ... European Respiratory Journal 29 (5), 834-860, 2007 | 535 | 2007 |
| Inhibition of Wnt/β-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis WR Henderson Jr, EY Chi, X Ye, C Nguyen, Y Tien, B Zhou, Z Borok, ... Proceedings of the National Academy of Sciences 107 (32), 14309-14314, 2010 | 529 | 2010 |
| Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells N Asokananthan, PT Graham, J Fink, DA Knight, AJ Bakker, AS McWilliam, ... The Journal of Immunology 168 (7), 3577-3585, 2002 | 516 | 2002 |
| Induction of epithelial–mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-β1 TL Hackett, SM Warner, D Stefanowicz, F Shaheen, DV Pechkovsky, ... American journal of respiratory and critical care medicine 180 (2), 122-133, 2009 | 486 | 2009 |
| Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ... American journal of respiratory and critical care medicine 196 (3), 283-297, 2017 | 418 | 2017 |
| Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma DA Knight, S Lim, AK Scaffidi, N Roche, KF Chung, GA Stewart, ... Journal of Allergy and Clinical Immunology 108 (5), 797-803, 2001 | 342 | 2001 |
| Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath C Lane, D Knight, S Burgess, P Franklin, F Horak, J Legg, A Moeller, ... Thorax 59 (9), 757-760, 2004 | 329 | 2004 |
| Airway epithelial regulation of pulmonary immune homeostasis and inflammation TS Hallstrand, TL Hackett, WA Altemeier, G Matute-Bello, PM Hansbro, ... Clinical immunology 151 (1), 1-15, 2014 | 291 | 2014 |
| Structural changes in the airways in asthma: observations and consequences TR Bai, DA Knight Clinical science 108 (6), 463-477, 2005 | 287 | 2005 |
| Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma A Kicic, EN Sutanto, PT Stevens, DA Knight, SM Stick American journal of respiratory and critical care medicine 174 (10), 1110-1118, 2006 | 265 | 2006 |
| Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution TL Hackett, GK Singhera, F Shaheen, P Hayden, GR Jackson, RG Hegele, ... American journal of respiratory cell and molecular biology 45 (5), 1090-1100, 2011 | 259 | 2011 |
| Epithelial cell dysfunction, a major driver of asthma development IH Heijink, VNS Kuchibhotla, MP Roffel, T Maes, DA Knight, I Sayers, ... Allergy 75 (8), 1902-1917, 2020 | 258 | 2020 |
| The processes and mechanisms of cardiac and pulmonary fibrosis LA Murtha, MJ Schuliga, NS Mabotuwana, SA Hardy, DW Waters, ... Frontiers in physiology 8, 777, 2017 | 221 | 2017 |
| Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation C Lang, C Murgia, M Leong, LW Tan, G Perozzi, D Knight, R Ruffin, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (2 …, 2007 | 218 | 2007 |
| The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter JA Hirota, SA Hirota, SM Warner, D Stefanowicz, F Shaheen, PL Beck, ... Journal of Allergy and Clinical Immunology 129 (4), 1116-1125. e6, 2012 | 217 | 2012 |
| Inverse effects of interleukin-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs YP Moodley, NLA Misso, AK Scaffidi, M Fogel-Petrovic, RJ McAnulty, ... American journal of respiratory cell and molecular biology 29 (4), 490-498, 2003 | 217 | 2003 |
| Adenosine A3 receptor expression and function in eosinophils. BA Walker, MA Jacobson, DA Knight, CA Salvatore, T Weir, D Zhou, ... American journal of respiratory cell and molecular biology 16 (5), 531-537, 1997 | 212 | 1997 |
| Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation YP Moodley, AK Scaffidi, NL Misso, C Keerthisingam, RJ McAnulty, ... The American journal of pathology 163 (1), 345-354, 2003 | 196 | 2003 |
| Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations A Singanayagam, N Glanville, JL Girkin, YM Ching, A Marcellini, ... Nature communications 9 (1), 2229, 2018 | 194 | 2018 |
Tillie L HackettProfessor, Department of Anesthesiology, Pharmacology, Therapeutics, University of British ColumbiaVerified email at hli.ubc.ca
