An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ... Nature 577 (7791), 572-575, 2020 | 176 | 2020 |
Control of cyclic oligoadenylate synthesis in a type III CRISPR system C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White Elife 7, e36734, 2018 | 156 | 2018 |
Ring nucleases deactivate type III CRISPR ribonucleases by degrading cyclic oligoadenylate JS Athukoralage, C Rouillon, S Graham, S Grüschow, MF White Nature 562 (7726), 277-280, 2018 | 123 | 2018 |
Bacteriophages inhibit and evade cGAS-like immune function in bacteria E Huiting, X Cao, J Ren, JS Athukoralage, Z Luo, S Silas, N An, H Carion, ... Cell 186 (4), 864-876. e21, 2023 | 83 | 2023 |
A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator JS Athukoralage, S Graham, S Grüschow, C Rouillon, MF White Journal of molecular biology 431 (15), 2894-2899, 2019 | 82 | 2019 |
Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence S Grüschow, JS Athukoralage, S Graham, T Hoogeboom, MF White Nucleic acids research 47 (17), 9259-9270, 2019 | 64 | 2019 |
Cyclic nucleotide signaling in phage defense and counter-defense JS Athukoralage, MF White Annual Review of Virology 9, 451-468, 2022 | 61 | 2022 |
The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling JS Athukoralage, S Graham, C Rouillon, S Grüschow, CM Czekster, ... Elife 9, e55852, 2020 | 57 | 2020 |
Bridge RNAs direct programmable recombination of target and donor DNA MG Durrant, NT Perry, JJ Pai, AR Jangid, JS Athukoralage, M Hiraizumi, ... Nature 630 (8018), 984-993, 2024 | 47* | 2024 |
Cyclic oligoadenylate signaling and regulation by ring nucleases during type III CRISPR defense JS Athukoralage, MF White RNA 27 (8), 855-867, 2021 | 42 | 2021 |
Investigation of the cyclic oligoadenylate signaling pathway of type III CRISPR systems C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White Methods in Enzymology 616, 191-218, 2019 | 35 | 2019 |
Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage JS Athukoralage, S McQuarrie, S Grüschow, S Graham, TM Gloster, ... Elife 9, e57627, 2020 | 32 | 2020 |
Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence A Samolygo, JS Athukoralage, S Graham, MF White Nucleic Acids Research 48 (11), 6149-6156, 2020 | 31 | 2020 |
Structural mechanism of bridge RNA-guided recombination M Hiraizumi, NT Perry, MG Durrant, T Soma, N Nagahata, S Okazaki, ... Nature 630 (8018), 994-1002, 2024 | 23 | 2024 |
Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open S McQuarrie, JS Athukoralage, SA McMahon, S Graham, K Ackermann, ... Nucleic Acids Research 51 (19), 10590-10605, 2023 | 11 | 2023 |
Ring nuclease MF White, J Athukoralage US Patent App. 17/432,201, 2023 | | 2023 |
Killing the messenger: discovery of enzymes degrading cyclic oligoadenylate defence activators synthesised by type III CRISPR immune systems JS Athukoralage University of St Andrews, 2021 | | 2021 |