| Site‐specific hyperphosphorylation inhibits, rather than promotes, tau fibrillization, seeding capacity, and its microtubule binding M Haj‐Yahya, P Gopinath, K Rajasekhar, H Mirbaha, MI Diamond, ... Angewandte Chemie International Edition 59 (10), 4059-4067, 2020 | 93 | 2020 |
| Chemical and semisynthetic approaches to study and target deubiquitinases P Gopinath, S Ohayon, M Nawatha, A Brik Chemical Society Reviews 45 (15), 4171-4198, 2016 | 91 | 2016 |
| Role of post‐translational modifications in Alzheimer's disease M Ramesh, P Gopinath, T Govindaraju ChemBioChem 21 (8), 1052-1079, 2020 | 71 | 2020 |
| Amelioration of acrylamide induced neurotoxicity by benzo [b] thiophene analogs via glutathione redox dynamics in zebrafish larvae B Haridevamuthu, T Manjunathan, A Guru, CRW Alphonse, S Boopathi, ... Brain Research 1788, 147941, 2022 | 56 | 2022 |
| Hydroxyl containing benzo [b] thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle B Haridevamuthu, T Manjunathan, A Guru, RS Kumar, R Rajagopal, ... Life Sciences 298, 120507, 2022 | 51 | 2022 |
| 6‐Gingerol and semisynthetic 6‐gingerdione counteract oxidative stress induced by ros in zebrafish T Manjunathan, A Guru, J Arokiaraj, P Gopinath Chemistry & Biodiversity 18 (12), e2100650, 2021 | 49 | 2021 |
| Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of … G Sudhakaran, P Prathap, A Guru, B Haridevamuthu, R Murugan, ... Molecular and cellular biochemistry 477 (10), 2387-2401, 2022 | 44 | 2022 |
| Anti‐inflammatory role demonstrated both in vitro and in vivo models using non‐steroidal tetranortriterpenoid, Nimbin (N1) and its analogues (N2 and N3) that alleviate the … G Sudhakaran, P Prathap, A Guru, R Rajesh, S Sathish, T Madhavan, ... Cell Biology International, 2022 | 44 | 2022 |
| Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach R Murugan, R Rajesh, B Seenivasan, B Haridevamuthu, G Sudhakaran, ... Microbial Pathogenesis 172, 105778, 2022 | 41 | 2022 |
| Highly chemoselective esterification reactions and Boc/THP/TBDMS discriminating deprotections under Samarium (III) Catalysis P Gopinath, S Nilaya, KM Muraleedharan Organic Letters 13 (8), 1932-1935, 2011 | 40 | 2011 |
| Understanding and predicting the potency of ROS-based enzyme inhibitors, exemplified by naphthoquinones and ubiquitin specific protease-2 P Gopinath, A Mahammed, S Ohayon, Z Gross, A Brik Chemical Science 7 (12), 7079-7086, 2016 | 37 | 2016 |
| Trihydroxy piperlongumine protects aluminium induced neurotoxicity in zebrafish: behavioral and biochemical approach B Haridevamuthu, D Raj, D Kesavan, S Muthuraman, RS Kumar, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2023 | 27 | 2023 |
| Deacetylepoxyazadiradione Derived from Epoxyazadiradione of Neem (Azadirachta indica A. Juss) Fruits Mitigates LPS‐Induced Oxidative Stress and … R Murugan, R Rajesh, A Guru, B Haridevamuthu, BO Almutairi, ... Chemistry & Biodiversity 19 (9), e202200041, 2022 | 26 | 2022 |
| Hepatoprotective effect of dihydroxy piperlongumine in high cholesterol-induced non-alcoholic fatty liver disease zebrafish via antioxidant activity B Haridevamuthu, B Seenivasan, PS Priya, S Muthuraman, RS Kumar, ... European Journal of Pharmacology 945, 175605, 2023 | 24 | 2023 |
| Nimbin analog N2 alleviates high testosterone induced oxidative stress in CHO cells and alters the expression of Tox3 and Dennd1a signal transduction pathway … G Sudhakaran, R Rajesh, R Murugan, M Velayutham, A Guru, S Boopathi, ... Phytotherapy Research 37 (4), 1449-1461, 2023 | 21 | 2023 |
| Broad spectrum anti-infective properties of benzisothiazolones and the parallels in their anti-bacterial and anti-fungal effects P Gopinath, RK Yadav, PK Shukla, K Srivastava, SK Puri, ... Bioorganic & Medicinal Chemistry Letters 27 (5), 1291-1295, 2017 | 21 | 2017 |
| Synthesis of coumaperine derivatives: Their NF-κB inhibitory effect, inhibition of cell migration and their cytotoxic activity N Nandakumar, S Muthuraman, P Gopinath, P Nithya, J Gopas, ... European Journal of Medicinal Chemistry 125, 1076-1087, 2017 | 18 | 2017 |
| Nanoencapsulation of Ru(p-cymene) Complex Bearing Ginger-based Natural Product into Liposomal Nanoformulation to Improve Its Cellular Uptake and … C Sumithaa, T Manjunathan, O Mazuryk, S Peters, RS Pillai, M Brindell, ... ACS Applied Bio Materials 5 (7), 3241-3256, 2022 | 14 | 2022 |
| Deacetylated nimbin analog N2 fortifies alloxan-induced pancreatic β-cell damage in insulin-resistant zebrafish larvae by upregulating phosphoenolpyruvate carboxykinase (PEPCK … G Sudhakaran, R Rajesh, A Guru, B Haridevamuthu, R Murugan, ... Toxicology and Applied Pharmacology 454, 116229, 2022 | 13 | 2022 |
| As many as six tandem reactions in one step! Unprecedented formation of highly functionalized benzothiophenes P. Gopinath , S.Nilaya, D.R. Tripathy, V. Ramkumar K.M. Muraleedharan Chemical Communications, 7131-7133, 2009 | 13 | 2009 |
ashraf brikProfessor of ChemistryVerified email at technion.ac.il