| Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity S Kousteni, T Bellido, LI Plotkin, CA O'brien, DL Bodenner, L Han, K Han, ... Cell 104 (5), 719-730, 2001 | 1574 | 2001 |
| Matrix-embedded cells control osteoclast formation J Xiong, M Onal, RL Jilka, RS Weinstein, SC Manolagas, CA O'brien Nature medicine 17 (10), 1235-1241, 2011 | 1486 | 2011 |
| Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength CA O’brien, D Jia, LI Plotkin, T Bellido, CC Powers, SA Stewart, ... Endocrinology 145 (4), 1835-1841, 2004 | 949 | 2004 |
| Estrogens and androgens in skeletal physiology and pathophysiology M Almeida, MR Laurent, V Dubois, F Claessens, CA O'Brien, R Bouillon, ... Physiological reviews 97 (1), 135-187, 2017 | 829 | 2017 |
| Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids M Almeida, LI Han, M Martin-Millan, LI Plotkin, SA Stewart, PK Roberson, ... Journal of Biological Chemistry 282 (37), 27285-27297, 2007 | 780 | 2007 |
| Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis T Bellido, AA Ali, I Gubrij, LI Plotkin, Q Fu, CA O’brien, SC Manolagas, ... Endocrinology 146 (11), 4577-4583, 2005 | 721 | 2005 |
| The role of estrogen and androgen receptors in bone health and disease SC Manolagas, CA O'brien, M Almeida Nature Reviews Endocrinology 9 (12), 699, 2013 | 678 | 2013 |
| Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting β-catenin from T cell factor-to forkhead box O-mediated transcription M Almeida, L Han, M Martin-Millan, CA O'Brien, SC Manolagas Journal of Biological Chemistry 282 (37), 27298-27305, 2007 | 615 | 2007 |
| Reversal of bone loss in mice by nongenotropic signaling of sex steroids S Kousteni, JR Chen, T Bellido, L Han, AA Ali, CA O'Brien, L Plotkin, Q Fu, ... Science 298 (5594), 843-846, 2002 | 542 | 2002 |
| Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts: a putative explanation for why intermittent administration is … T Bellido, AA Ali, LI Plotkin, Q Fu, I Gubrij, PK Roberson, RS Weinstein, ... Journal of Biological Chemistry 278 (50), 50259-50272, 2003 | 463 | 2003 |
| Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density D Jia, CA O’brien, SA Stewart, SC Manolagas, RS Weinstein Endocrinology 147 (12), 5592-5599, 2006 | 447 | 2006 |
| Control of bone mass and remodeling by PTH receptor signaling in osteocytes CA O'Brien, LI Plotkin, C Galli, JJ Goellner, AR Gortazar, MR Allen, ... PloS one 3 (8), e2942, 2008 | 442 | 2008 |
| Essential Requirement of BMPs‐2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin E Abe, M Yamamoto, Y Taguchi, B Lecka‐Czernik, CA O'Brien, ... Journal of Bone and Mineral Research 15 (4), 663-673, 2000 | 425 | 2000 |
| Osteocytes, not osteoblasts or lining cells, are the main source of the RANKL required for osteoclast formation in remodeling bone J Xiong, M Piemontese, M Onal, J Campbell, JJ Goellner, V Dusevich, ... PloS one 10 (9), e0138189, 2015 | 366 | 2015 |
| Osteocyte RANKL: new insights into the control of bone remodeling J Xiong, CA O'Brien Journal of Bone and Mineral Research 27 (3), 499-505, 2012 | 366 | 2012 |
| The estrogen receptor-α in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone M Martin-Millan, M Almeida, E Ambrogini, L Han, H Zhao, RS Weinstein, ... Molecular endocrinology 24 (2), 323-334, 2010 | 354 | 2010 |
| STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-κB ligand and stimulation of osteoclastogenesis by gp130-utilizing … CA O'Brien, I Gubrij, SC Lin, RL Saylors, SC Manolagas Journal of Biological Chemistry 274 (27), 19301-19308, 1999 | 324 | 1999 |
| FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice E Ambrogini, M Almeida, M Martin-Millan, JH Paik, RA DePinho, L Han, ... Cell metabolism 11 (2), 136-146, 2010 | 320 | 2010 |
| Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice RS Weinstein, C Wan, Q Liu, Y Wang, M Almeida, CA O’Brien, ... Aging cell 9 (2), 147-161, 2010 | 306 | 2010 |
| Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual M Almeida, S Iyer, M Martin-Millan, SM Bartell, L Han, E Ambrogini, ... The Journal of clinical investigation 123 (1), 2012 | 302 | 2012 |
Jilka,R.L.Research Professor of Internal MedicineVerified email at uams.edu