| RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN KD Foust, X Wang, VL McGovern, L Braun, AK Bevan, AM Haidet, TT Le, ... Nature biotechnology 28 (3), 271-274, 2010 | 887 | 2010 |
| Natural history of infantile‐onset spinal muscular atrophy SJ Kolb, CS Coffey, JW Yankey, K Krosschell, WD Arnold, SB Rutkove, ... Annals of neurology 82 (6), 883-891, 2017 | 400 | 2017 |
| Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose–response study in mice and nonhuman primates K Meyer, L Ferraiuolo, L Schmelzer, L Braun, V McGovern, S Likhite, ... Molecular Therapy 23 (3), 477-487, 2015 | 329 | 2015 |
| A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse PN Porensky, C Mitrpant, VL McGovern, AK Bevan, KD Foust, BK Kaspar, ... Human molecular genetics 21 (7), 1625-1638, 2012 | 317 | 2012 |
| Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery AK Bevan, KR Hutchinson, KD Foust, L Braun, VL McGovern, ... Human molecular genetics 19 (20), 3895-3905, 2010 | 258 | 2010 |
| Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect TO Gavrilina, VL McGovern, E Workman, TO Crawford, RG Gogliotti, ... Human molecular genetics 17 (8), 1063-1075, 2008 | 255 | 2008 |
| Embryonic motor axon development in the severe SMA mouse VL McGovern, TO Gavrilina, CE Beattie, AHM Burghes Human molecular genetics 17 (18), 2900-2909, 2008 | 199 | 2008 |
| Temporal requirement for high SMN expression in SMA mice TT Le, VL McGovern, IE Alwine, X Wang, A Massoni-Laporte, MM Rich, ... Human molecular genetics 20 (18), 3578-3591, 2011 | 152 | 2011 |
| A role for SMN exon 7 splicing in the selective vulnerability of motor neurons in spinal muscular atrophy M Ruggiu, VL McGovern, F Lotti, L Saieva, DK Li, S Kariya, UR Monani, ... Molecular and cellular biology, 2012 | 147 | 2012 |
| Baseline results of the Neuro NEXT spinal muscular atrophy infant biomarker study SJ Kolb, CS Coffey, JW Yankey, K Krosschell, WD Arnold, SB Rutkove, ... Annals of clinical and translational neurology 3 (2), 132-145, 2016 | 140 | 2016 |
| Electrophysiological biomarkers in spinal muscular atrophy: proof of concept WD Arnold, PN Porensky, VL McGovern, CC Iyer, S Duque, X Li, K Meyer, ... Annals of clinical and translational neurology 1 (1), 34, 2013 | 86 | 2013 |
| Complete sequencing of the SMN2 gene in SMA patients detects SMN gene deletion junctions and variants in SMN2 that modify the SMA phenotype C Ruhno, VL McGovern, MR Avenarius, PJ Snyder, TW Prior, FC Nery, ... Human genetics 138, 241-256, 2019 | 85 | 2019 |
| Biodistribution of onasemnogene abeparvovec DNA, mRNA and SMN protein in human tissue G Thomsen, AHM Burghes, C Hsieh, J Do, BTT Chu, S Perry, B Barkho, ... Nature medicine 27 (10), 1701-1711, 2021 | 76 | 2021 |
| SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA VL McGovern, CC Iyer, WD Arnold, SE Gombash, PG Zaworski, ... Human Molecular Genetics 24 (19), 5524-5541, 2015 | 68 | 2015 |
| SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice SE Gombash, CJ Cowley, JA Fitzgerald, CC Iyer, D Fried, VL McGovern, ... Human molecular genetics 24 (13), 3847-3860, 2015 | 64 | 2015 |
| Antisense oligonucleotides and spinal muscular atrophy: skipping along AHM Burghes, VL McGovern Genes & development 24 (15), 1574-1579, 2010 | 62 | 2010 |
| Plastin 3 expression does not modify spinal muscular atrophy severity in the∆ 7 SMA mouse VL McGovern, A Massoni-Laporte, X Wang, TT Le, HT Le, CE Beattie, ... PloS one 10 (7), e0132364, 2015 | 61 | 2015 |
| Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA CC Iyer, VL McGovern, JD Murray, SE Gombash, PG Zaworski, KD Foust, ... Human molecular genetics 24 (21), 6160-6173, 2015 | 60 | 2015 |
| The neuromuscular impact of symptomatic SMN restoration in a mouse model of spinal muscular atrophy W Arnold, VL McGovern, B Sanchez, J Li, KM Corlett, SJ Kolb, ... Neurobiology of disease 87, 116-123, 2016 | 49 | 2016 |
| NeuroNEXT Clinical Trial Network on behalf of the NN101 SMA Biomarker Investigators SJ Kolb, CS Coffey, JW Yankey, K Krosschell, WD Arnold, SB Rutkove, ... Natural history of infantile-onset spinal muscular atrophy. Ann Neurol 82 (6 …, 2017 | 42 | 2017 |
Arthur BurghesProfessor Molecular and Cellular BiochemistryVerified email at osu.edu
