| Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3644 | 2010 |
| Vascular risk factors and diabetic neuropathy S Tesfaye, N Chaturvedi, SEM Eaton, JD Ward, C Manes, ... New England Journal of Medicine 352 (4), 341-350, 2005 | 1912 | 2005 |
| Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps A Mahajan, D Taliun, M Thurner, NR Robertson, JM Torres, NW Rayner, ... Nature genetics 50 (11), 1505-1513, 2018 | 1756 | 2018 |
| Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, ... Nature genetics 42 (11), 949-960, 2010 | 1136 | 2010 |
| Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study AG Tabák, M Jokela, TN Akbaraly, EJ Brunner, M Kivimäki, DR Witte The Lancet 373 (9682), 2215-2221, 2009 | 1092 | 2009 |
| Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways RA Scott, V Lagou, RP Welch, E Wheeler, ME Montasser, J Luan, R Mägi, ... Nature genetics 44 (9), 991-1005, 2012 | 916 | 2012 |
| Rare and low-frequency coding variants alter human adult height E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ... Nature 542 (7640), 186-190, 2017 | 684 | 2017 |
| Endothelial function predicts progression of carotid intima-media thickness JPJ Halcox, AE Donald, E Ellins, DR Witte, MJ Shipley, EJ Brunner, ... Circulation 119 (7), 1005-1012, 2009 | 456 | 2009 |
| Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ... Nature genetics 50 (4), 559-571, 2018 | 455 | 2018 |
| Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ... Nature genetics 54 (5), 560-572, 2022 | 454 | 2022 |
| Psychosocial stress at work doubles the risk of type 2 diabetes in middle-aged women: evidence from the Whitehall II study A Heraclides, T Chandola, DR Witte, EJ Brunner Diabetes care 32 (12), 2230-2235, 2009 | 384 | 2009 |
| Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ... Nature genetics 50 (1), 26-41, 2018 | 373 | 2018 |
| Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality EJ Brunner, A Mosdøl, DR Witte, P Martikainen, M Stafford, MJ Shipley, ... The American journal of clinical nutrition 87 (5), 1414-1421, 2008 | 351 | 2008 |
| Genetic evidence of assortative mating in humans MR Robinson, A Kleinman, M Graff, AAE Vinkhuyzen, D Couper, ... Nature Human Behaviour 1 (1), 0016, 2017 | 348 | 2017 |
| New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism M Horikoshi, H Yaghootkar, DO Mook-Kanamori, U Sovio, HR Taal, ... Nature genetics 45 (1), 76-82, 2013 | 342 | 2013 |
| A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B T Yamauchi, K Hara, S Maeda, K Yasuda, A Takahashi, M Horikoshi, ... Nature genetics 42 (10), 864-868, 2010 | 336 | 2010 |
| A germline variant in the TP53 polyadenylation signal confers cancer susceptibility SN Stacey, P Sulem, A Jonasdottir, G Masson, J Gudmundsson, ... Nature genetics 43 (11), 1098-1103, 2011 | 331 | 2011 |
| Relationship between risk factors and mortality in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study (PCS) SS Soedamah-Muthu, N Chaturvedi, DR Witte, LK Stevens, M Porta, ... Diabetes care 31 (7), 1360-1366, 2008 | 321 | 2008 |
| GLP-1 response to oral glucose is reduced in prediabetes, screen-detected type 2 diabetes, and obesity and influenced by sex: the ADDITION-PRO study K Færch, SS Torekov, D Vistisen, NB Johansen, DR Witte, A Jonsson, ... Diabetes 64 (7), 2513-2525, 2015 | 314 | 2015 |
| Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ... Nature 570 (7759), 71-76, 2019 | 312 | 2019 |
Eric BrunnerProfessor of social and biological epidemiology, University College LondonVerified email at ucl.ac.uk