A review of HER4 (ErbB4) kinase, its impact on cancer, and its inhibitors MI El-Gamal, NH Mewafi, NE Abdelmotteleb, MA Emara, H Tarazi, ... Molecules 26 (23), 7376, 2021 | 51 | 2021 |
Evaluation of substituted pyrazole-based kinase inhibitors in one decade (2011–2020): Current status and future prospects MI El-Gamal, SO Zaraei, MM Madkour, HS Anbar Molecules 27 (1), 330, 2022 | 36 | 2022 |
Sulfamates in drug design and discovery: pre-clinical and clinical investigations SO Zaraei, AR Abduelkarem, HS Anbar, S Kobeissi, M Mohammad, ... European Journal of Medicinal Chemistry 179, 257-271, 2019 | 34 | 2019 |
Discovery of first-in-class imidazothiazole-based potent and selective ErbB4 (HER4) kinase inhibitors SO Zaraei, RM Sbenati, NN Alach, HS Anbar, R El-Gamal, H Tarazi, ... European Journal of Medicinal Chemistry 224, 113674, 2021 | 26 | 2021 |
Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase S Ullah, MI El-Gamal, S Zaib, HS Anbar, SO Zaraei, RM Sbenati, ... Bioorganic Chemistry 99, 103783, 2020 | 25 | 2020 |
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase MI El-Gamal, S Ullah, SO Zaraei, S Jalil, S Zaib, DM Zaher, HA Omar, ... European Journal of Medicinal Chemistry 181, 111560, 2019 | 25 | 2019 |
A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation MI El-Gamal, SO Zaraei, PA Foster, HS Anbar, R El-Gamal, R El-Awady, ... Bioorganic & Medicinal Chemistry 28 (8), 115406, 2020 | 22 | 2020 |
Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl) pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors EMH Ali, RFA El-Telbany, MS Abdel-Maksoud, UM Ammar, KI Mersal, ... European Journal of Medicinal Chemistry 215, 113277, 2021 | 20 | 2021 |
Discovery of urease inhibitory effect of sulfamate derivatives: Biological and computational studies S Zaib, MT Younas, SO Zaraei, I Khan, HS Anbar, MI El-Gamal Bioorganic Chemistry 119, 105545, 2022 | 19 | 2022 |
Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative … RM Sbenati, SO Zaraei, MI El-Gamal, HS Anbar, H Tarazi, MM Zoghbor, ... European journal of medicinal chemistry 210, 113081, 2021 | 19 | 2021 |
Design and synthesis of new quinoline derivatives as selective C-RAF kinase inhibitors with potent anticancer activity SO Zaraei, NN Al-Ach, HS Anbar, R El-Gamal, H Tarazi, RT Tokatly, ... European Journal of Medicinal Chemistry 238, 114434, 2022 | 18 | 2022 |
Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer … HS Anbar, R El-Gamal, S Ullah, SO Zaraei, M Al-Rashida, S Zaib, ... Bioorganic Chemistry 104, 104305, 2020 | 18 | 2020 |
Design and synthesis of novel anti-urease imidazothiazole derivatives with promising antibacterial activity against Helicobacter pylori AI Shahin, S Zaib, SO Zaraei, RA Kedia, HS Anbar, MT Younas, TH Al-Tel, ... PLoS One 18 (6), e0286684, 2023 | 14 | 2023 |
Structural optimization of 4-(imidazol-5-yl) pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: synthesis … EMH Ali, KI Mersal, UM Ammar, SO Zaraei, MS Abdel-Maksoud, ... European Journal of Pharmaceutical Sciences 171, 106115, 2022 | 13 | 2022 |
Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors SO Zaraei, MI El-Gamal, Z Shafique, ST Amjad, S Afridi, S Zaib, HS Anbar, ... Bioorganic & Medicinal Chemistry 27 (17), 3889-3901, 2019 | 11 | 2019 |
Diarylamides in anticancer drug discovery: A review of pre-clinical and clinical investigations AR Abduelkarem, HS Anbar, SO Zaraei, AA Alfar, OS Al-Zoubi, ... European Journal of Medicinal Chemistry 188, 112029, 2020 | 10 | 2020 |
Design, synthesis, and biological evaluation of a new series of pyrazole derivatives: Discovery of potent and selective JNK3 kinase inhibitors RRA Rabah, A Sebastian, S Vunnam, S Sultan, H Tarazi, HS Anbar, ... Bioorganic & Medicinal Chemistry 69, 116894, 2022 | 9 | 2022 |
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents AI Shahin, SO Zaraei, BO AlKubaisi, S Ullah, HS Anbar, R El-Gamal, ... European Journal of Medicinal Chemistry 246, 114958, 2023 | 8 | 2023 |
Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, ... European Journal of Medicinal Chemistry 261, 115779, 2023 | 6 | 2023 |
Anti-proliferative activity of RIHMS-Qi-23 against MCF-7 breast cancer cell line is through inhibition of cell proliferation and senescence but not inhibition of targeted kinases R El-Gamal, S Elfarrash, M El-Nablaway, AA Salem, SO Zaraei, HS Anbar, ... BMC cancer 23 (1), 1053, 2023 | 4 | 2023 |