| Metabolic profiling using stable isotope tracing reveals distinct patterns of glucose utilization by physiologically activated CD8+ T cells EH Ma, MJ Verway, RM Johnson, DG Roy, M Steadman, S Hayes, ... Immunity 51 (5), 856-870. e5, 2019 | 352 | 2019 |
| Methionine metabolism shapes T helper cell responses through regulation of epigenetic reprogramming DG Roy, J Chen, V Mamane, EH Ma, BM Muhire, RD Sheldon, ... Cell metabolism 31 (2), 250-266. e9, 2020 | 259 | 2020 |
| Itaconate confers tolerance to late NLRP3 inflammasome activation M Bambouskova, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, ... Cell reports 34 (10), 2021 | 165 | 2021 |
| Impact of acute exposure to increased hydrostatic pressure and reduced shear rate on conduit artery endothelial function: a limb-specific response J Padilla, RD Sheldon, DM Sitar, SC Newcomer American Journal of Physiology-Heart and Circulatory Physiology 297 (3 …, 2009 | 138 | 2009 |
| ER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis D DeZwaan-McCabe, RD Sheldon, MC Gorecki, DF Guo, ER Gansemer, ... Cell reports 19 (9), 1794-1806, 2017 | 101 | 2017 |
| Carbon source availability drives nutrient utilization in CD8+ T cells I Kaymak, KM Luda, LR Duimstra, EH Ma, J Longo, MS Dahabieh, ... Cell metabolism 34 (9), 1298-1311. e6, 2022 | 96 | 2022 |
| Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1 Y Zhao, Z Liu, G Liu, Y Zhang, S Liu, D Gan, W Chang, X Peng, ES Sung, ... Cell metabolism 35 (10), 1688-1703. e10, 2023 | 87 | 2023 |
| The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity AJ Rauckhorst, LR Gray, RD Sheldon, X Fu, AD Pewa, CR Feddersen, ... Molecular metabolism 6 (11), 1468-1479, 2017 | 83 | 2017 |
| Structure of an AMPK complex in an inactive, ATP-bound state Y Yan, S Mukherjee, KG Harikumar, TS Strutzenberg, XE Zhou, ... Science 373 (6553), 413-419, 2021 | 81 | 2021 |
| Disrupting mitochondrial pyruvate uptake directs glutamine into the TCA cycle away from glutathione synthesis and impairs hepatocellular tumorigenesis SC Tompkins, RD Sheldon, AJ Rauckhorst, MF Noterman, SR Solst, ... Cell reports 28 (10), 2608-2619. e6, 2019 | 80 | 2019 |
| Aerobic exercise training in the treatment of non‐alcoholic fatty liver disease related fibrosis MA Linden, RD Sheldon, GM Meers, LC Ortinau, EM Morris, FW Booth, ... The Journal of physiology 594 (18), 5271-5284, 2016 | 72 | 2016 |
| Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness A Sharma, L Oonthonpan, RD Sheldon, AJ Rauckhorst, Z Zhu, ... Elife 8, e45873, 2019 | 67 | 2019 |
| Gestational exercise protects adult male offspring from high-fat diet-induced hepatic steatosis RD Sheldon, AN Blaize, JA Fletcher, KJ Pearson, SS Donkin, ... Journal of hepatology 64 (1), 171-178, 2016 | 67 | 2016 |
| 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer MK Kilgour, S MacPherson, LG Zacharias, AE Ellis, RD Sheldon, EY Liu, ... Science Advances 7 (4), eabe1174, 2021 | 65 | 2021 |
| Ketolysis drives CD8+ T cell effector function through effects on histone acetylation KM Luda, J Longo, SM Kitchen-Goosen, LR Duimstra, EH Ma, ... Immunity 56 (9), 2021-2035. e8, 2023 | 58 | 2023 |
| Acute impact of intermittent pneumatic leg compression frequency on limb hemodynamics, vascular function, and skeletal muscle gene expression in humans RD Sheldon, BT Roseguini, JP Thyfault, BD Crist, MH Laughlin, ... Journal of Applied Physiology 112 (12), 2099-2109, 2012 | 55 | 2012 |
| eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH RD Sheldon, GM Meers, EM Morris, MA Linden, RP Cunningham, ... American Journal of Physiology-Endocrinology and Metabolism 317 (4), E605-E616, 2019 | 51 | 2019 |
| New insights into the physiologic basis for intermittent pneumatic limb compression as a therapeutic strategy for peripheral artery disease RD Sheldon, BT Roseguini, MH Laughlin, SC Newcomer Journal of vascular surgery 58 (6), 1688-1696, 2013 | 50 | 2013 |
| Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II–driven respiration BD Fink, F Bai, L Yu, RD Sheldon, A Sharma, EB Taylor, WI Sivitz Journal of Biological Chemistry 293 (51), 19932-19941, 2018 | 46 | 2018 |
| Chronic NOS inhibition accelerates NAFLD progression in an obese rat model RD Sheldon, J Padilla, NT Jenkins, MH Laughlin, RS Rector American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (6 …, 2015 | 40 | 2015 |