| Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance J Zhang, X Bu, H Wang, Y Zhu, Y Geng, NT Nihira, Y Tan, Y Ci, F Wu, ... Nature 553 (7686), 91-95, 2018 | 890 | 2018 |
| DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage N Taira, K Nihira, T Yamaguchi, Y Miki, K Yoshida Molecular cell 25 (5), 725-738, 2007 | 390 | 2007 |
| Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy Y Gao, NT Nihira, X Bu, C Chu, J Zhang, A Kolodziejczyk, Y Fan, NT Chan, ... Nature cell biology 22 (9), 1064-1075, 2020 | 277 | 2020 |
| DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells N Taira, R Mimoto, M Kurata, T Yamaguchi, M Kitagawa, Y Miki, ... The Journal of clinical investigation 122 (3), 859-872, 2012 | 180 | 2012 |
| G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells L Liu, W Michowski, H Inuzuka, K Shimizu, NT Nihira, JM Chick, N Li, ... Nature cell biology 19 (3), 177-188, 2017 | 144 | 2017 |
| DYRK2 controls the epithelial–mesenchymal transition in breast cancer by degrading Snail R Mimoto, N Taira, H Takahashi, T Yamaguchi, M Okabe, K Uchida, ... Cancer letters 339 (2), 214-225, 2013 | 109 | 2013 |
| ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage N Taira, H Yamamoto, T Yamaguchi, Y Miki, K Yoshida Journal of Biological Chemistry 285 (7), 4909-4919, 2010 | 79 | 2010 |
| Post-translational modifications of p53 tumor suppressor: determinants of its functional targets N Taira, K Yoshida F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de …, 2012 | 78 | 2012 |
| Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function NT Nihira, K Ogura, K Shimizu, BJ North, J Zhang, D Gao, H Inuzuka, ... Science signaling 10 (466), eaai8026, 2017 | 75 | 2017 |
| Protein kinase C δ activates topoisomerase IIα to induce apoptotic cell death in response to DNA damage K Yoshida, T Yamaguchi, H Shinagawa, N Taira, KI Nakayama, Y Miki Molecular and cellular biology 26 (9), 3414-3431, 2006 | 71 | 2006 |
| Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors E Clement, H Inuzuka, NT Nihira, W Wei, A Toker Science signaling 11 (521), eaao3810, 2018 | 62 | 2018 |
| TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress K Nihira, N Taira, Y Miki, K Yoshida Oncogene 27 (58), 7285-7295, 2008 | 62 | 2008 |
| Physiological functions of FBW7 in cancer and metabolism K Shimizu, NT Nihira, H Inuzuka, W Wei Cellular signalling 46, 15-22, 2018 | 60 | 2018 |
| Palmdelphin, a novel target of p53 with Ser46 phosphorylation, controls cell death in response to DNA damage N Dashzeveg, N Taira, ZG Lu, J Kimura, K Yoshida Cell death & disease 5 (5), e1221-e1221, 2014 | 58 | 2014 |
| The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis K Shimizu, H Fukushima, K Ogura, EC Lien, NT Nihira, J Zhang, BJ North, ... Science signaling 10 (460), eaah4117, 2017 | 55 | 2017 |
| A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress J Kimura, ST Nguyen, H Liu, N Taira, Y Miki, K Yoshida Nucleic acids research 36 (16), 5250-5259, 2008 | 52 | 2008 |
| Induction of amphiregulin by p53 promotes apoptosis via control of microRNA biogenesis in response to DNA damage N Taira, T Yamaguchi, J Kimura, ZG Lu, S Fukuda, S Higashiyama, M Ono, ... Proceedings of the National Academy of Sciences 111 (2), 717-722, 2014 | 51 | 2014 |
| Engagement of DYRK2 in proper control for cell division NT Nihira, K Yoshida Cell Cycle 14 (6), 802-807, 2015 | 42 | 2015 |
| Programmed cell death 6, a novel p53‐responsive gene, targets to the nucleus in the apoptotic response to DNA damage K Suzuki, N Dashzeveg, ZG Lu, N Taira, Y Miki, K Yoshida Cancer science 103 (10), 1788-1794, 2012 | 33 | 2012 |
| Diminished DYRK2 sensitizes hormone receptor-positive breast cancer to everolimus by the escape from degrading mTOR R Mimoto, NT Nihira, S Hirooka, H Takeyama, K Yoshida Cancer Letters 384, 27-38, 2017 | 26 | 2017 |
