| Comparative functional genomics of the fission yeasts N Rhind, Z Chen, M Yassour, DA Thompson, BJ Haas, N Habib, ... Science 332 (6032), 930-936, 2011 | 550 | 2011 |
| A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death Y Guo, C Chen, Y Zheng, J Zhang, X Tao, S Liu, D Zheng, Y Liu Journal of Biological Chemistry 280 (51), 41940-41952, 2005 | 105 | 2005 |
| High-throughput sequencing of retrotransposon integration provides a saturated profile of target activity in Schizosaccharomyces pombe Y Guo, HL Levin Genome research 20 (2), 239-248, 2010 | 92 | 2010 |
| PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis X Zhou, BL Updegraff, Y Guo, M Peyton, L Girard, JE Larsen, XJ Xie, ... Cancer research 77 (1), 187-197, 2017 | 73 | 2017 |
| Integration profiling of gene function with dense maps of transposon integration Y Guo, JM Park, B Cui, E Humes, S Gangadharan, S Hung, PC FitzGerald, ... Genetics 195 (2), 599-609, 2013 | 72 | 2013 |
| Poly (ADP‐ribosyl) ation of BRD 7 by PARP 1 confers resistance to DNA‐damaging chemotherapeutic agents K Hu, W Wu, Y Li, L Lin, D Chen, H Yan, X Xiao, H Chen, Z Chen, ... EMBO reports 20 (5), e46166, 2019 | 47 | 2019 |
| Transmembrane protease TMPRSS11B promotes lung cancer growth by enhancing lactate export and glycolytic metabolism BL Updegraff, X Zhou, Y Guo, MS Padanad, PH Chen, C Yang, ... Cell reports 25 (8), 2223-2233. e6, 2018 | 41 | 2018 |
| Combination of AAV-TRAIL with miR-221-Zip therapeutic strategy overcomes the resistance to TRAIL induced apoptosis in liver cancer S Ma, J Sun, Y Guo, P Zhang, Y Liu, D Zheng, J Shi Theranostics 7 (13), 3228, 2017 | 36 | 2017 |
| Therapeutic expression of an anti-death receptor 5 single-chain fixed-variable region prevents tumor growth in mice J Shi, Y Liu, Y Zheng, Y Guo, J Zhang, P Cheung, R Xu, D Zheng Cancer research 66 (24), 11946-11953, 2006 | 34 | 2006 |
| Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis Y Guo, BL Updegraff, S Park, D Durakoglugil, VH Cruz, S Maddux, ... Cancer research 76 (4), 773-786, 2016 | 33 | 2016 |
| Serial number tagging reveals a prominent sequence preference of retrotransposon integration AG Chatterjee, C Esnault, Y Guo, S Hung, PG McQueen, HL Levin Nucleic acids research 42 (13), 8449-8460, 2014 | 30 | 2014 |
| High-performance gene expression and knockout tools using sleeping beauty transposon system K Hu, Y Li, W Wu, H Chen, Z Chen, Y Zhang, Y Guo, D Yin Mobile Dna 9, 1-13, 2018 | 25 | 2018 |
| A long terminal repeat retrotransposon of Schizosaccharomyces japonicus integrates upstream of RNA pol III transcribed genes Y Guo, PK Singh, HL Levin Mobile DNA 6, 1-7, 2015 | 20 | 2015 |
| Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells Y Liu, G Ma, Z Gao, J Li, J Wang, X Zhu, R Ma, J Yang, Y Zhou, K Hu, ... Nucleic Acids Research 50 (6), 3456-3474, 2022 | 17 | 2022 |
| Identification of an integrase-independent pathway of retrotransposition F Li, M Lee, C Esnault, K Wendover, Y Guo, P Atkins, M Zaratiegui, ... Science Advances 8 (26), eabm9390, 2022 | 11 | 2022 |
| Sleeping Beauty transposon integrates into non-TA dinucleotides Y Guo, Y Zhang, K Hu Mobile DNA 9, 1-7, 2018 | 11 | 2018 |
| Anti-human trail receptor DR5 monoclonal antibody (AD5-10), method thereof and use of the same Y Liu, Y Guo, D Zheng US Patent 7,893,216, 2011 | 11 | 2011 |
| Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon Y Zhang, YX Huang, X Jin, J Chen, L Peng, DL Wang, Y Li, XY Yao, ... Journal of Nanobiotechnology 19, 1-17, 2021 | 10 | 2021 |
| Oleic acid-PPARγ-FABP4 loop fuels cholangiocarcinoma colonization in lymph node metastases microenvironment H Zhang, K Zhu, R Zhang, Y Guo, J Wang, C Liu, X Lu, Z Zhou, W Wu, ... Hepatology 80 (1), 69-86, 2024 | 4 | 2024 |
| The integration preference of sleeping beauty at non-TA site is related to the transposon end sequences Y Zhou, G Ma, J Yang, Z Gao, Y Guo Frontiers in Genetics 12, 639125, 2021 | 3 | 2021 |
Kathryn A. O'DonnellAssociate Professor of Molecular Biology, UT Southwestern Medical CenterVerified email at UTSouthwestern.edu