| Leptin receptor signaling in midbrain dopamine neurons regulates feeding JD Hommel, R Trinko, RM Sears, D Georgescu, ZW Liu, XB Gao, ... neuron 51 (6), 801-810, 2006 | 1107 | 2006 |
| Local gene knockdown in the brain using viral-mediated RNA interference JD Hommel, RM Sears, D Georgescu, DL Simmons, RJ DiLeone Nature medicine 9 (12), 1539-1544, 2003 | 456 | 2003 |
| The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm JE LeDoux, J Moscarello, R Sears, V Campese Molecular psychiatry 22 (1), 24-36, 2017 | 386 | 2017 |
| The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance D Georgescu, RM Sears, JD Hommel, M Barrot, CA Bolaños, DJ Marsh, ... Journal of Neuroscience 25 (11), 2933-2940, 2005 | 368 | 2005 |
| Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus RM Sears, AE Fink, MB Wigestrand, CR Farb, L De Lecea, JE LeDoux Proceedings of the National Academy of Sciences 110 (50), 20260-20265, 2013 | 243 | 2013 |
| Active avoidance requires a serial basal amygdala to nucleus accumbens shell circuit F Ramirez, JM Moscarello, JE LeDoux, RM Sears Journal of Neuroscience 35 (8), 3470-3477, 2015 | 224 | 2015 |
| Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone RM Sears, RJ Liu, NS Narayanan, R Sharf, MF Yeckel, M Laubach, ... Journal of Neuroscience 30 (24), 8263-8273, 2010 | 121 | 2010 |
| Active vs. reactive threat responding is associated with differential c-Fos expression in specific regions of amygdala and prefrontal cortex RCR Martinez, N Gupta, G Lázaro-Muñoz, RM Sears, S Kim, ... Learning & memory 20 (8), 446-452, 2013 | 105 | 2013 |
| Neural mechanisms underlying obesity and drug addiction R Trinko, RM Sears, DJ Guarnieri, RJ DiLeone Physiology & behavior 91 (5), 499-505, 2007 | 97 | 2007 |
| Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity NC Anastasio, SJ Stutz, LHL Fink, SE Swinford-Jackson, RM Sears, ... ACS chemical neuroscience 6 (7), 1248-1258, 2015 | 92 | 2015 |
| Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence NC Anastasio, SJ Stutz, RG Fox, RM Sears, RB Emeson, RJ DiLeone, ... Neuropsychopharmacology 39 (2), 360-372, 2014 | 88 | 2014 |
| A brainstem-central amygdala circuit underlies defensive responses to learned threats Y Gu, WT Piper, LA Branigan, EM Vazey, G Aston-Jones, L Lin, ... Molecular psychiatry 25 (3), 640-654, 2020 | 70 | 2020 |
| β-Adrenergic receptors regulate the acquisition and consolidation phases of aversive memory formation through distinct, temporally regulated signaling pathways HC Schiff, JP Johansen, M Hou, DEA Bush, EK Smith, JAE Klein, ... Neuropsychopharmacology 42 (4), 895-903, 2017 | 68 | 2017 |
| Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala LE Ostroff, E Santini, R Sears, Z Deane, RN Kanadia, JE LeDoux, ... Elife 8, e51607, 2019 | 67 | 2019 |
| Molecular mechanisms of threat learning in the lateral nucleus of the amygdala RM Sears, HC Schiff, JE LeDoux Progress in Molecular Biology and Translational Science 122, 263-304, 2014 | 59 | 2014 |
| Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat JD Mul, SE La Fleur, PW Toonen, A Afrasiab-Middelman, R Binnekade, ... PloS one 6 (5), e19600, 2011 | 55 | 2011 |
| The neural foundations of reaction and action in aversive motivation VD Campese, RM Sears, JM Moscarello, L Diaz-Mataix, CK Cain, ... Behavioral neuroscience of motivation, 171-195, 2016 | 43 | 2016 |
| Erk1/2 mediates leptin receptor signaling in the ventral tegmental area R Trinko, G Gan, XB Gao, RM Sears, DJ Guarnieri, RJ DiLeone PloS one 6 (11), e27180, 2011 | 42 | 2011 |
| Characterization of the amplificatory effect of norepinephrine in the acquisition of Pavlovian threat associations L Díaz-Mataix, WT Piper, HC Schiff, CH Roberts, VD Campese, RM Sears, ... Learning & memory 24 (9), 432-439, 2017 | 35 | 2017 |
| Primary auditory cortex regulates threat memory specificity MB Wigestrand, HC Schiff, M Fyhn, JE LeDoux, RM Sears Learning & Memory 24 (1), 55-58, 2017 | 30 | 2017 |
Ralph DiLeoneProfessor of Psychiatry and of NeuroscienceVerified email at yale.edu
