| NADPH oxidase–derived superoxide anion mediates angiotensin ii–induced pressor effect via activation of p38 mitogen–activated protein kinase in the rostral ventrolateral medulla SHH Chan, KS Hsu, CC Huang, LL Wang, CC Ou, JYH Chan Circulation research 97 (8), 772-780, 2005 | 259 | 2005 |
| Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation KLH Wu, SHH Chan, JYH Chan Journal of neuroinflammation 9, 1-15, 2012 | 211 | 2012 |
| Reduction in molecular synthesis or enzyme activity of superoxide dismutases and catalase contributes to oxidative stress and neurogenic hypertension in spontaneously … SHH Chan, MH Tai, CY Li, JYH Chan Free Radical Biology and Medicine 40 (11), 2028-2039, 2006 | 179 | 2006 |
| Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus YH Ho, YT Lin, CWJ Wu, YM Chao, AYW Chang, JYH Chan Journal of biomedical science 22, 1-14, 2015 | 173 | 2015 |
| Redox signaling in pathophysiology of hypertension M Majzunova, I Dovinova, M Barancik, JYH Chan Journal of biomedical science 20, 1-10, 2013 | 161 | 2013 |
| Oxidative impairment of mitochondrial electron transport chain complexes in rostral ventrolateral medulla contributes to neurogenic hypertension SHH Chan, KLH Wu, AYW Chang, MH Tai, JYH Chan Hypertension 53 (2), 217-227, 2009 | 147 | 2009 |
| Differential cardiovascular responses to blockade of nNOS or iNOS in rostral ventrolateral medulla of the rat SHH Chan, LL Wang, SH Wang, JYH Chan British journal of pharmacology 133 (4), 606-614, 2001 | 131 | 2001 |
| Heat shock protein 70 confers cardiovascular protection during endotoxemia via inhibition of nuclear factor-κB activation and inducible nitric oxide synthase expression in the … JYH Chan, CC Ou, LL Wang, SHH Chan Circulation 110 (23), 3560-3566, 2004 | 121 | 2004 |
| Participation of paraventricular nucleus of hypothalamus in central regulation of penile erection in the rat KK Chen, SHH Chan, LS Chang, JYH Chan The Journal of urology 158 (1), 238-244, 1997 | 117 | 1997 |
| Potentiation of baroreceptor reflex response by heat shock protein 70 in nucleus tractus solitarii confers cardiovascular protection during heatstroke PL Li, YM Chao, SHH Chan, JYH Chan Circulation 103 (16), 2114-2119, 2001 | 112 | 2001 |
| Dopaminergic neurotransmission at the paraventricular nucleus of hypothalamus in central regulation of penile erection in the rat KKUO CHEN, JYH CHAN, LS CHANG The Journal of urology 162 (1), 237-242, 1999 | 110 | 1999 |
| Brain stem NOS and ROS in neural mechanisms of hypertension SHH Chan, JYH Chan Antioxidants & redox signaling 20 (1), 146-163, 2014 | 108 | 2014 |
| Increased superoxide anion in rostral ventrolateral medulla contributes to hypertension in spontaneously hypertensive rats via interactions with nitric oxide MH Tai, LL Wang, KLH Wu, JYH Chan Free radical biology and medicine 38 (4), 450-462, 2005 | 105 | 2005 |
| Hypertension programmed by perinatal high-fat diet: effect of maternal gut microbiota-targeted therapy CN Hsu, CY Hou, JYH Chan, CT Lee, YL Tain Nutrients 11 (12), 2908, 2019 | 103 | 2019 |
| Facilitation of lumbar monosynaptic reflexes by locus coeruleus in the rat JYH Chan, SJ Fung, SHH Chan, CD Barnes Brain research 369 (1-2), 103-109, 1986 | 102 | 1986 |
| Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension SHH Chan, CA Wu, KLH Wu, YH Ho, AYW Chang, JYH Chan Circulation research 105 (9), 886-896, 2009 | 101 | 2009 |
| Melatonin prevents maternal fructose intake‐induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites YL Tain, S Leu, KLH Wu, WC Lee, JYH Chan Journal of pineal research 57 (1), 80-89, 2014 | 99 | 2014 |
| Intracavernous pressure as an experimental index in a rat model for the evaluation of penile erection KK Chen, JYH Chan, LS Chang, MT Chen, SHH Chan The Journal of urology 147 (4), 1124-1128, 1992 | 87 | 1992 |
| Transcriptional upregulation of brain-derived neurotrophic factor in rostral ventrolateral medulla by angiotensin II: significance in superoxide homeostasis and neural … SHH Chan, CWJ Wu, AYW Chang, KS Hsu, JYH Chan Circulation Research 107 (9), 1127-1139, 2010 | 86 | 2010 |
| Activation of endogenous antioxidants as a common therapeutic strategy against cancer, neurodegeneration and cardiovascular diseases: A lesson learnt from DJ-1 JYH Chan, SHH Chan Pharmacology & therapeutics 156, 69-74, 2015 | 85 | 2015 |
Samuel H.H. ChanDistinguihsed Chair Professor of Translational Medicine, Chang Gung Memorial HospitalVerified email at adm.cgmh.org.tw