Click and release: bioorthogonal approaches to “on-demand” activation of prodrugs X Ji, Z Pan, B Yu, LK De La Cruz, Y Zheng, B Ke, B Wang Chemical Society Reviews 48 (4), 1077-1094, 2019 | 275 | 2019 |
Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide Y Zheng, X Ji, B Yu, K Ji, D Gallo, E Csizmadia, M Zhu, MR Choudhury, ... Nature chemistry 10 (7), 787-794, 2018 | 272 | 2018 |
Toward carbon monoxide–based therapeutics: Critical drug delivery and developability issues X Ji, K Damera, Y Zheng, B Yu, LE Otterbein, B Wang Journal of pharmaceutical sciences 105 (2), 406-416, 2016 | 176 | 2016 |
Strategies toward organic carbon monoxide prodrugs X Ji, B Wang Accounts of Chemical Research 51 (6), 1377-1385, 2018 | 167 | 2018 |
Click and release: a chemical strategy toward developing gasotransmitter prodrugs by using an intramolecular Diels–Alder reaction X Ji, C Zhou, K Ji, RE Aghoghovbia, Z Pan, V Chittavong, B Ke, B Wang Angewandte Chemie International Edition 55 (51), 15846-15851, 2016 | 159 | 2016 |
Hydrogen sulfide prodrugs—a review Y Zheng, X Ji, K Ji, B Wang Acta Pharmaceutica Sinica B 5 (5), 367-377, 2015 | 134 | 2015 |
Strategies to target the Hedgehog signaling pathway for cancer therapy M Xin, X Ji, LK De La Cruz, S Thareja, B Wang Medicinal Research Reviews 38 (3), 870-913, 2018 | 109 | 2018 |
Medicinal chemistry strategies toward host targeting antiviral agents X Ji, Z Li Medicinal Research Reviews 40 (5), 1519-1557, 2020 | 103 | 2020 |
Carbon monoxide protects the kidney through the central circadian clock and CD39 M Correa-Costa, D Gallo, E Csizmadia, E Gomperts, JL Lieberum, ... Proceedings of the National Academy of Sciences 115 (10), E2302-E2310, 2018 | 81 | 2018 |
pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates X Ji, LKC De La Cruz, Z Pan, V Chittavong, B Wang Chemical Communications 53 (69), 9628-9631, 2017 | 79 | 2017 |
An esterase-activated click and release approach to metal-free CO-prodrugs X Ji, K Ji, V Chittavong, B Yu, Z Pan, B Wang Chemical Communications 53 (59), 8296-8299, 2017 | 78 | 2017 |
Organic CO prodrugs: Structure–CO‐release rate relationship studies Z Pan, V Chittavong, W Li, J Zhang, K Ji, M Zhu, X Ji, B Wang Chemistry–A European Journal 23 (41), 9838-9845, 2017 | 74 | 2017 |
Sulfur dioxide prodrugs: triggered release of SO 2 via a click reaction W Wang, X Ji, Z Du, B Wang Chemical Communications 53 (8), 1370-1373, 2017 | 70 | 2017 |
Esterase-sensitive and pH-controlled carbon monoxide prodrugs for treating systemic inflammation X Ji, Z Pan, C Li, T Kang, LKC De La Cruz, L Yang, Z Yuan, B Ke, B Wang Journal of Medicinal Chemistry 62 (6), 3163-3168, 2019 | 69 | 2019 |
Organic CO prodrugs activated by endogenous ROS Z Pan, J Zhang, K Ji, V Chittavong, X Ji, B Wang Organic letters 20 (1), 8-11, 2018 | 65 | 2018 |
Click, release, and fluoresce: a chemical strategy for a cascade prodrug system for codelivery of carbon monoxide, a drug payload, and a fluorescent reporter LKC De La Cruz, SL Benoit, Z Pan, B Yu, RJ Maier, X Ji, B Wang Organic letters 20 (4), 897-900, 2018 | 56 | 2018 |
Click and fluoresce: a bioorthogonally activated smart probe for wash-free fluorescent labeling of biomolecules X Ji, K Ji, V Chittavong, RE Aghoghovbia, M Zhu, B Wang The Journal of organic chemistry 82 (3), 1471-1476, 2017 | 44 | 2017 |
A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition Y Yang, P Gao, Y Liu, X Ji, M Gan, Y Guan, X Hao, Z Li, C Xiao Bioorganic & medicinal chemistry letters 21 (13), 3943-3946, 2011 | 43 | 2011 |
Chemiexcitation‐Triggered Prodrug Activation for Targeted Carbon Monoxide Delivery Q Min, Z Ni, M You, M Liu, Z Zhou, H Ke, X Ji Angewandte Chemie 134 (26), e202200974, 2022 | 39 | 2022 |
Click and Release: SO2 Prodrugs with Tunable Release Rates X Ji, EM El-Labbad, K Ji, DS Lasheen, RAT Serya, KA Abouzid, B Wang Organic letters 19 (4), 818-821, 2017 | 39 | 2017 |