| In vivo effects of a GPR30 antagonist MK Dennis, R Burai, C Ramesh, WK Petrie, SN Alcon, TK Nayak, ... Nature chemical biology 5 (6), 421-427, 2009 | 625 | 2009 |
| Câncer e agentes antineoplásicos ciclo-celular específicos e ciclo-celular não específicos que interagem com o DNA: uma introdução VL Almeida, A Leitão, LCB Reina, CA Montanari, CL Donnici, MTP Lopes Química nova 28, 118-129, 2005 | 495 | 2005 |
| Novel derivatives of 1, 3, 4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays AS Kiselyov, MN Semenova, NB Chernyshova, A Leitao, AV Samet, ... European journal of medicinal chemistry 45 (5), 1683-1697, 2010 | 107 | 2010 |
| Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors LAA Avelar, CD Camilo, S de Albuquerque, WB Fernandes, C Gonçalez, ... PLoS Negl Trop Dis 9 (7), e0003916, 2015 | 87 | 2015 |
| Molecular design, synthesis and trypanocidal activity of dipeptidyl nitriles as cruzain inhibitors LAA Avelar, CD Camilo, S de Albuquerque, WB Fernandes, C Gonçalez, ... PLoS neglected tropical diseases 9 (7), e0003916, 2015 | 87 | 2015 |
| Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen EA Ariazi, A Leitao, TI Oprea, B Chen, T Louis, AM Bertucci, CGN Sharma, ... Molecular cancer therapeutics 6 (11), 2817-2827, 2007 | 76 | 2007 |
| Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity? L Cianni, CW Feldmann, E Gilberg, M Gütschow, L Juliano, A Leitão, ... Journal of medicinal chemistry 62 (23), 10497-10525, 2019 | 66 | 2019 |
| Ligand efficiency metrics considered harmful PW Kenny, A Leitão, CA Montanari Journal of computer-aided molecular design 28 (7), 699-710, 2014 | 65 | 2014 |
| Structure–activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase A Leitão, AD Andricopulo, G Oliva, MT Pupo, AA de Marchi, PC Vieira, ... Bioorganic & medicinal chemistry letters 14 (9), 2199-2204, 2004 | 63 | 2004 |
| Characterization, solubility and biological activity of amphihilic biopolymeric Schiff bases synthesized using chitosans HFG Barbosa, M Attjioui, A Leitão, BM Moerschbacher, ÉTG Cavalheiro Carbohydrate polymers 220, 1-11, 2019 | 60 | 2019 |
| Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles AM Dos Santos, L Cianni, D De Vita, F Rosini, A Leitão, CA Laughton, ... Physical Chemistry Chemical Physics 20 (37), 24317-24328, 2018 | 53 | 2018 |
| Small molecule inhibitors of hantavirus infection PR Hall, A Leitão, C Ye, K Kilpatrick, B Hjelle, TI Oprea, RS Larson Bioorganic & medicinal chemistry letters 20 (23), 7085-7091, 2010 | 51 | 2010 |
| A comparative study of warheads for design of cysteine protease inhibitors DG Silva, JFR Ribeiro, D De Vita, L Cianni, CH Franco, LH Freitas-Junior, ... Bioorganic & Medicinal Chemistry Letters, 2017 | 50 | 2017 |
| Chitosan‐laponite nanocomposite scaffolds for wound dressing application VAM Gonzaga, AL Poli, JS Gabriel, DY Tezuka, TA Valdes, A Leitão, ... Journal of Biomedical Materials Research Part B: Applied Biomaterials 108 (4 …, 2020 | 43 | 2020 |
| Nitriles: an attractive approach to the development of covalent inhibitors V Bonatto, RF Lameiro, FR Rocho, J Lameira, A Leitão, CA Montanari RSC Medicinal Chemistry, 2023 | 42 | 2023 |
| Assessment of the Cruzain Cysteine Protease Reversible and Irreversible Covalent Inhibition Mechanism JRA Silva, L Cianni, D Araujo, PHJ Batista, D De Vita, F Rosini, A Leitão, ... Journal of Chemical Information and Modeling 60 (3), 1666-1677, 2020 | 42 | 2020 |
| Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors ACB Burtoloso, S de Albuquerque, M Furber, JC Gomes, C Gonçalez, ... PLOS Neglected Tropical Diseases 11 (2), e0005343, 2017 | 42 | 2017 |
| Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart R Hromas, EA Williamson, S Fnu, YJ Lee, SJ Park, BD Beck, JS You, ... Oncogene 31 (38), 4245-4254, 2012 | 42 | 2012 |
| Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt® high-throughput flow cytometry system MK Haynes, JJ Strouse, A Waller, A Leitao, RF Curpan, C Bologa, ... Journal of biomolecular screening 14 (6), 596-609, 2009 | 42 | 2009 |
| Targeting the transposase domain of the DNA repair component Metnase to enhance chemotherapy EA Williamson, L Damiani, A Leitao, C Hu, H Hathaway, T Oprea, L Sklar, ... Cancer research 72 (23), 6200-6208, 2012 | 38 | 2012 |
Carlos Alberto MontanariUniversity of Sao PauloVerified email at usp.br