| Identification of cancer driver genes based on nucleotide context F Dietlein, D Weghorn, A Taylor-Weiner, A Richters, B Reardon, D Liu, ... Nature genetics 52 (2), 208-218, 2020 | 240 | 2020 |
| A framework for identification of actionable cancer genome dependencies in small cell lung cancer ML Sos, F Dietlein, M Peifer, J Schöttle, H Balke-Want, C Müller, M Koker, ... Proceedings of the National Academy of Sciences 109 (42), 17034-17039, 2012 | 206 | 2012 |
| A synergistic interaction between Chk1-and MK2 inhibitors in KRAS-mutant cancer F Dietlein, B Kalb, M Jokic, EM Noll, A Strong, L Tharun, L Ozretić, ... Cell 162 (1), 146-159, 2015 | 142 | 2015 |
| Targeting drug resistance in EGFR with covalent inhibitors: a structure-based design approach J Engel, A Richters, M Getlik, S Tomassi, M Keul, M Termathe, J Lategahn, ... Journal of medicinal chemistry 58 (17), 6844-6863, 2015 | 122 | 2015 |
| Cell-Autonomous and Non–Cell-Autonomous Mechanisms of Transformation by Amplified FGFR1 in Lung Cancer F Malchers, F Dietlein, J Schöttle, X Lu, L Nogova, K Albus, ... Cancer discovery 4 (2), 246-257, 2014 | 119 | 2014 |
| Covalent‐allosteric kinase inhibitors J Weisner, R Gontla, L van der Westhuizen, S Oeck, J Ketzer, P Janning, ... Angewandte Chemie International Edition 54 (35), 10313-10316, 2015 | 116* | 2015 |
| Proteus in the world of proteins: conformational changes in protein kinases M Rabiller, M Getlik, S Klüter, A Richters, S Tückmantel, JR Simard, ... Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2010 | 111 | 2010 |
| Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against … C Tintori, AL Fallacara, M Radi, C Zamperini, E Dreassi, E Crespan, ... Journal of Medicinal Chemistry 58 (1), 347-361, 2015 | 88 | 2015 |
| De Novo Design of Protein Kinase Inhibitors by in Silico Identification of Hinge Region-Binding Fragments R Urich, G Wishart, M Kiczun, A Richters, N Tidten-Luksch, D Rauh, ... ACS chemical biology 8 (5), 1044-1052, 2013 | 71 | 2013 |
| Phenotypic identification of a novel autophagy inhibitor chemotype targeting lipid kinase VPS34 L Robke, L Laraia, MA Carnero Corrales, G Konstantinidis, M Muroi, ... Angewandte Chemie International Edition 56 (28), 8153-8157, 2017 | 68 | 2017 |
| Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors A Richters, SK Doyle, DB Freeman, C Lee, BS Leifer, S Jagannathan, ... Cell chemical biology 28 (2), 134-147. e14, 2021 | 67 | 2021 |
| Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors D Plenker, M Riedel, J Brägelmann, MA Dammert, R Chauhan, ... Science translational medicine 9 (394), eaah6144, 2017 | 67 | 2017 |
| Neuritogenic militarinone‐inspired 4‐hydroxypyridones target the stress pathway kinase MAP4K4 P Schröder, T Förster, S Kleine, C Becker, A Richters, S Ziegler, D Rauh, ... Angewandte Chemie 127 (42), 12575-12580, 2015 | 66 | 2015 |
| Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR D Basu, A Richters, D Rauh Bioorganic & Medicinal Chemistry 23 (12), 2767-2780, 2015 | 53 | 2015 |
| Systematic kinase inhibitor profiling identifies CDK9 as a synthetic lethal target in NUT midline carcinoma J Brägelmann, MA Dammert, F Dietlein, JM Heuckmann, A Choidas, ... Cell reports 20 (12), 2833-2845, 2017 | 52 | 2017 |
| Targeting protein arginine methyltransferase 5 in disease A Richters Future medicinal chemistry 9 (17), 2081-2098, 2017 | 47 | 2017 |
| Identification of type II and III DDR2 inhibitors A Richters, HD Nguyen, T Phan, JR Simard, C Grütter, J Engel, D Rauh Journal of medicinal chemistry 57 (10), 4252-4262, 2014 | 43 | 2014 |
| Identification and further development of potent TBK1 inhibitors A Richters, D Basu, J Engel, MS Ercanoglu, H Balke-Want, R Tesch, ... ACS chemical biology 10 (1), 289-298, 2015 | 38 | 2015 |
| Epigenetic modulation using small molecules-targeting histone acetyltransferases in disease A Richters, A N Koehler Current medicinal chemistry 24 (37), 4121-4150, 2017 | 34 | 2017 |
| A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase A Koch, HB Rode, A Richters, D Rauh, S Hauf ACS chemical biology 7 (4), 723-731, 2012 | 34 | 2012 |
Herbert WaldmannMax-Planck-Institut DortmundVerified email at mpi-dortmund.mpg.de