Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration D Gordon, G Pavlovska, CP Glover, JB Uney, D Wraith, NJ Scolding Neuroscience letters 448 (1), 71-73, 2008 | 160 | 2008 |
Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis BL Conway-Campbell, JW Wooh, AJ Brooks, D Gordon, RJ Brown, ... Proceedings of the National Academy of Sciences 104 (33), 13331-13336, 2007 | 130 | 2007 |
Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis D Gordon, G Pavlovska, JB Uney, DC Wraith, NJ Scolding Journal of Neuropathology & Experimental Neurology 69 (11), 1087-1095, 2010 | 124 | 2010 |
Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells K Kemp, D Gordon, DC Wraith, E Mallam, E Hartfield, J Uney, A Wilkins, ... Neuropathology and applied neurobiology 37 (2), 166-178, 2011 | 100 | 2011 |
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor … D Gordon, R Dafinca, J Scaber, J Alegre-Abarrategui, L Farrimond, ... Neurobiology of disease 121, 148-162, 2019 | 80 | 2019 |
TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca2+ signaling in motor neurons R Mutihac, J Alegre-Abarrategui, D Gordon, L Farrimond, ... Neurobiology of disease 75, 64-77, 2015 | 77 | 2015 |
Mice carrying ALS mutant TDP-43, but not mutant FUS, display in vivo defects in axonal transport of signaling endosomes JN Sleigh, AP Tosolini, D Gordon, A Devoy, P Fratta, EMC Fisher, ... Cell Reports 30 (11), 3655-3662. e2, 2020 | 67 | 2020 |
An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress E Feneberg, D Gordon, AG Thompson, MJ Finelli, R Dafinca, A Candalija, ... Neurobiology of disease 144, 105050, 2020 | 31 | 2020 |
Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo MG Williamson, MJ Finelli, JN Sleigh, A Reddington, D Gordon, K Talbot, ... Human Molecular Genetics 28 (21), 3584-3599, 2019 | 26 | 2019 |
Human mesenchymal stem cell culture for neural transplantation D Gordon, NJ Scolding Neural Cell Transplantation: Methods and Protocols, 103-118, 2009 | 24 | 2009 |
Enhanced green fluorescent protein-expressing human mesenchymal stem cells retain neural marker expression D Gordon, CP Glover, AM Merrison, JB Uney, NJ Scolding Journal of neuroimmunology 193 (1-2), 59-67, 2008 | 23 | 2008 |
Antisense suppression of tau in cultured rat oligodendrocytes inhibits process formation D Gordon, GJ Kidd, R Smith Journal of neuroscience research 86 (12), 2591-2601, 2008 | 17 | 2008 |
Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice A Dubinski, M Gagné, S Peyrard, D Gordon, K Talbot, C Vande Velde Human Molecular Genetics 32 (2), 319-332, 2023 | 14 | 2023 |
ALS mice carrying pathological mutant TDP-43, but not mutant FUS, display axonal transport defects in vivo JN Sleigh, AP Tosolini, D Gordon, A Devoy, P Fratta, EMC Fisher, ... BioRxiv, 438812, 2018 | 7 | 2018 |
Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43 E Christoforidou, FA Simoes, D Gordon, K Talbot, M Hafezparast Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24 (7-8), 746-755, 2023 | 3 | 2023 |
TDP-43 is cytoplasmically mislocalized and associated with impaired stress responses and survival of primary neurons from symptomatic amyotrophic lateral sclerosis (ALS) mice L Farrimond, D Gordon, R Mutihac, J Alegre-Abarrategui, B Davies, ... EUROPEAN JOURNAL OF NEUROLOGY 23, 390-391, 2016 | | 2016 |
Absence of wide-spread mis-splicing in the preclinical phase of a native promoter driven TDP-43 mouse model of ALS J Scaber, D Gordon, R Mutihac, J Alegre-Abarrategui, J Riancho, D Sims, ... NEUROMUSCULAR DISORDERS 26, S31-S31, 2016 | | 2016 |
Motor disorders D Gordon, K Talbot Behavioral Genetics of the Mouse: Volume 2, Genetic Mouse Models of …, 2014 | | 2014 |
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (P3. 012) K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ... Neurology 82 (10_supplement), P3. 012, 2014 | | 2014 |
Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis (I11-1.007) K Talbot, D Gordon, R Mutihac, J Alegre-Abarrategui, L Farrimond, ... Neurology 82 (10 Supplement), 2014 | | 2014 |