Shearing of synovial fluid activates latent TGF-β MB Albro, AD Cigan, RJ Nims, KJ Yeroushalmi, SR Oungoulian, CT Hung, ... Osteoarthritis and cartilage 20 (11), 1374-1382, 2012 | 125 | 2012 |
Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β MB Albro, RJ Nims, KM Durney, AD Cigan, JJ Shim, G Vunjak-Novakovic, ... Biomaterials 77, 173-185, 2016 | 82 | 2016 |
High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties AD Cigan, BL Roach, RJ Nims, AR Tan, MB Albro, AM Stoker, JL Cook, ... Journal of biomechanics 49 (9), 1909-1917, 2016 | 78 | 2016 |
Accumulation of exogenous activated TGF-β in the superficial zone of articular cartilage MB Albro, RJ Nims, AD Cigan, KJ Yeroushalmi, T Alliston, CT Hung, ... Biophysical journal 104 (8), 1794-1804, 2013 | 75 | 2013 |
Ex vivo deformations of the urinary bladder wall during whole bladder filling: contributions of extracellular matrix and smooth muscle A Parekh, AD Cigan, S Wognum, RL Heise, MB Chancellor, MS Sacks Journal of biomechanics 43 (9), 1708-1716, 2010 | 62 | 2010 |
Insulin, Ascorbate, and Glucose Have a Much Greater Influence Than Transferrin and Selenous Acid on the In Vitro Growth of Engineered Cartilage in … AD Cigan, RJ Nims, MB Albro, JD Esau, MP Dreyer, G Vunjak-Novakovic, ... Tissue Engineering Part A 19 (17-18), 1941-1948, 2013 | 57 | 2013 |
Matrix production in large engineered cartilage constructs is enhanced by nutrient channels and excess media supply RJ Nims, AD Cigan, MB Albro, G Vunjak-Novakovic, CT Hung, ... Tissue Engineering Part C: Methods 21 (7), 747-757, 2015 | 51 | 2015 |
Continuum theory of fibrous tissue damage mechanics using bond kinetics: application to cartilage tissue engineering RJ Nims, KM Durney, AD Cigan, A Dusséaux, CT Hung, GA Ateshian Interface Focus 6 (1), 20150063, 2016 | 46 | 2016 |
Dynamic mechanical compression of devitalized articular cartilage does not activate latent TGF-β MB Albro, RJ Nims, AD Cigan, KJ Yeroushalmi, JJ Shim, CT Hung, ... Journal of biomechanics 46 (8), 1433-1439, 2013 | 45 | 2013 |
Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels RJ Nims, AD Cigan, MB Albro, CT Hung, GA Ateshian Journal of biomechanics 47 (9), 2165-2172, 2014 | 41 | 2014 |
Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs AD Cigan, RJ Nims, MB Albro, G Vunjak-Novakovic, CT Hung, ... Journal of biomechanics 47 (16), 3847-3854, 2014 | 35 | 2014 |
Nutrient channels aid the growth of articular surface-sized engineered cartilage constructs AD Cigan, KM Durney, RJ Nims, G Vunjak-Novakovic, CT Hung, ... Tissue Engineering Part A 22 (17-18), 1063-1074, 2016 | 29 | 2016 |
Time and dose-dependent effects of chondroitinase ABC on growth of engineered cartilage GD O’Connell, RJ Nims, J Green, AD Cigan, GA Ateshian, CT Hung European cells & materials 27, 312, 2014 | 29 | 2014 |
Expression of doublecortin reveals articular chondrocyte lineage in mouse embryonic limbs Q Zhang, AD Cigan, L Marrero, C Lopreore, S Liu, D Ge, FH Savoie, ... Genesis 49 (2), 75-82, 2011 | 25 | 2011 |
Constrained cage culture improves engineered cartilage functional properties by enhancing collagen network stability RJ Nims, AD Cigan, KM Durney, BK Jones, JD O'Neill, WSA Law, ... Tissue Engineering Part A 23 (15-16), 847-858, 2017 | 21 | 2017 |
Optimizing nutrient channel spacing and revisiting TGF-beta in large engineered cartilage constructs AD Cigan, RJ Nims, G Vunjak-Novakovic, CT Hung, GA Ateshian Journal of biomechanics 49 (10), 2089-2094, 2016 | 12 | 2016 |
Synovial fluid and physiologic levels of cortisol, insulin, and glucose in media maintain the homeostasis of immature bovine cartilage explants over long term culture MB Albro, KM Durney, JJ Shim, A Singh, AD Cigan, RJ Nims, BK Jones, ... Orthopedic Research Society Annual Meeting, 2014 | 4 | 2014 |
Effects of media stirring and presence of nutrient channels on functional properties of large engineered cartilage constructs AD Cigan, RJ Nims, MB Albro, CT Hung, GA Ateshian Summer Bioengineering Conference 55614, V01BT39A001, 2013 | 3 | 2013 |
Insulin and ascorbate have a much greater influence than transferrin and selenous acid on the growth of engineered cartilage in chondrogenic media AD Cigan, RJ Nims, MB Albro, SL Breves, CT Hung, GA Ateshian Summer Bioengineering Conference 44809, 1141-1142, 2012 | 2 | 2012 |
Damage mechanics in tissue engineered cartilage: biochemical data and computational models RJ Nims, KM Durney, AD Cigan, A Dusseaux, CT Hung, GA Ateshian | | 2015 |