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Alexander Cigan
Alexander Cigan
Verified email at columbia.edu
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Year
Shearing of synovial fluid activates latent TGF-β
MB Albro, AD Cigan, RJ Nims, KJ Yeroushalmi, SR Oungoulian, CT Hung, ...
Osteoarthritis and cartilage 20 (11), 1374-1382, 2012
1252012
Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β
MB Albro, RJ Nims, KM Durney, AD Cigan, JJ Shim, G Vunjak-Novakovic, ...
Biomaterials 77, 173-185, 2016
822016
High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties
AD Cigan, BL Roach, RJ Nims, AR Tan, MB Albro, AM Stoker, JL Cook, ...
Journal of biomechanics 49 (9), 1909-1917, 2016
782016
Accumulation of exogenous activated TGF-β in the superficial zone of articular cartilage
MB Albro, RJ Nims, AD Cigan, KJ Yeroushalmi, T Alliston, CT Hung, ...
Biophysical journal 104 (8), 1794-1804, 2013
752013
Ex vivo deformations of the urinary bladder wall during whole bladder filling: contributions of extracellular matrix and smooth muscle
A Parekh, AD Cigan, S Wognum, RL Heise, MB Chancellor, MS Sacks
Journal of biomechanics 43 (9), 1708-1716, 2010
622010
Insulin, Ascorbate, and Glucose Have a Much Greater Influence Than Transferrin and Selenous Acid on the In Vitro Growth of Engineered Cartilage in …
AD Cigan, RJ Nims, MB Albro, JD Esau, MP Dreyer, G Vunjak-Novakovic, ...
Tissue Engineering Part A 19 (17-18), 1941-1948, 2013
572013
Matrix production in large engineered cartilage constructs is enhanced by nutrient channels and excess media supply
RJ Nims, AD Cigan, MB Albro, G Vunjak-Novakovic, CT Hung, ...
Tissue Engineering Part C: Methods 21 (7), 747-757, 2015
512015
Continuum theory of fibrous tissue damage mechanics using bond kinetics: application to cartilage tissue engineering
RJ Nims, KM Durney, AD Cigan, A Dusséaux, CT Hung, GA Ateshian
Interface Focus 6 (1), 20150063, 2016
462016
Dynamic mechanical compression of devitalized articular cartilage does not activate latent TGF-β
MB Albro, RJ Nims, AD Cigan, KJ Yeroushalmi, JJ Shim, CT Hung, ...
Journal of biomechanics 46 (8), 1433-1439, 2013
452013
Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels
RJ Nims, AD Cigan, MB Albro, CT Hung, GA Ateshian
Journal of biomechanics 47 (9), 2165-2172, 2014
412014
Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs
AD Cigan, RJ Nims, MB Albro, G Vunjak-Novakovic, CT Hung, ...
Journal of biomechanics 47 (16), 3847-3854, 2014
352014
Nutrient channels aid the growth of articular surface-sized engineered cartilage constructs
AD Cigan, KM Durney, RJ Nims, G Vunjak-Novakovic, CT Hung, ...
Tissue Engineering Part A 22 (17-18), 1063-1074, 2016
292016
Time and dose-dependent effects of chondroitinase ABC on growth of engineered cartilage
GD O’Connell, RJ Nims, J Green, AD Cigan, GA Ateshian, CT Hung
European cells & materials 27, 312, 2014
292014
Expression of doublecortin reveals articular chondrocyte lineage in mouse embryonic limbs
Q Zhang, AD Cigan, L Marrero, C Lopreore, S Liu, D Ge, FH Savoie, ...
Genesis 49 (2), 75-82, 2011
252011
Constrained cage culture improves engineered cartilage functional properties by enhancing collagen network stability
RJ Nims, AD Cigan, KM Durney, BK Jones, JD O'Neill, WSA Law, ...
Tissue Engineering Part A 23 (15-16), 847-858, 2017
212017
Optimizing nutrient channel spacing and revisiting TGF-beta in large engineered cartilage constructs
AD Cigan, RJ Nims, G Vunjak-Novakovic, CT Hung, GA Ateshian
Journal of biomechanics 49 (10), 2089-2094, 2016
122016
Synovial fluid and physiologic levels of cortisol, insulin, and glucose in media maintain the homeostasis of immature bovine cartilage explants over long term culture
MB Albro, KM Durney, JJ Shim, A Singh, AD Cigan, RJ Nims, BK Jones, ...
Orthopedic Research Society Annual Meeting, 2014
42014
Effects of media stirring and presence of nutrient channels on functional properties of large engineered cartilage constructs
AD Cigan, RJ Nims, MB Albro, CT Hung, GA Ateshian
Summer Bioengineering Conference 55614, V01BT39A001, 2013
32013
Insulin and ascorbate have a much greater influence than transferrin and selenous acid on the growth of engineered cartilage in chondrogenic media
AD Cigan, RJ Nims, MB Albro, SL Breves, CT Hung, GA Ateshian
Summer Bioengineering Conference 44809, 1141-1142, 2012
22012
Damage mechanics in tissue engineered cartilage: biochemical data and computational models
RJ Nims, KM Durney, AD Cigan, A Dusseaux, CT Hung, GA Ateshian
2015
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