| Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs T Bepler, A Morin, M Rapp, J Brasch, L Shapiro, AJ Noble, B Berger Nature methods 16 (11), 1153-1160, 2019 | 1065 | 2019 |
| Topaz-Denoise: general deep denoising models for cryoEM and cryoET T Bepler, K Kelley, AJ Noble, B Berger Nature communications 11 (1), 5208, 2020 | 370 | 2020 |
| Routine single particle CryoEM sample and grid characterization by tomography AJ Noble, VP Dandey, H Wei, J Brasch, J Chase, P Acharya, YZ Tan, ... Elife 7, e34257, 2018 | 299 | 2018 |
| Reducing effects of particle adsorption to the air–water interface in cryo-EM AJ Noble, H Wei, VP Dandey, Z Zhang, YZ Tan, CS Potter, B Carragher Nature methods 15 (10), 793-795, 2018 | 227 | 2018 |
| Routine determination of ice thickness for cryo-EM grids WJ Rice, A Cheng, AJ Noble, ET Eng, LY Kim, B Carragher, CS Potter Journal of structural biology 204 (1), 38-44, 2018 | 135 | 2018 |
| Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO J Chen, AJ Noble, JY Kang, SA Darst Journal of structural biology: X 1, 100005, 2019 | 133 | 2019 |
| Better, faster, cheaper: recent advances in cryo–electron microscopy EYD Chua, JH Mendez, M Rapp, SL Ilca, YZ Tan, K Maruthi, H Kuang, ... Annual review of biochemistry 91 (1), 1-32, 2022 | 106 | 2022 |
| Visualization of clustered protocadherin neuronal self-recognition complexes J Brasch, KM Goodman, AJ Noble, M Rapp, S Mannepalli, F Bahna, ... Nature 569 (7755), 280-283, 2019 | 97 | 2019 |
| Characterization of the SARS-CoV-2 S protein: biophysical, biochemical, structural, and antigenic analysis NG Herrera, NC Morano, A Celikgil, GI Georgiev, RJ Malonis, JH Lee, ... ACS omega 6 (1), 85-102, 2020 | 96 | 2020 |
| Waffle Method: A general and flexible approach for improving throughput in FIB-milling K Kelley, AM Raczkowski, O Klykov, P Jaroenlak, D Bobe, M Kopylov, ... Nature communications 13 (1), 1857, 2022 | 81 | 2022 |
| Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR NL Meyer, G Hu, O Davulcu, Q Xie, AJ Noble, C Yoshioka, DS Gingerich, ... Elife 8, e44707, 2019 | 80 | 2019 |
| ResLog plots as an empirical metric of the quality of cryo-EM reconstructions SM Stagg, AJ Noble, M Spilman, MS Chapman Journal of structural biology 185 (3), 418-426, 2014 | 76 | 2014 |
| Automated batch fiducial-less tilt-series alignment in Appion using Protomo AJ Noble, SM Stagg Journal of structural biology 192 (2), 270-278, 2015 | 75 | 2015 |
| The 2.8 Å electron microscopy structure of adeno-associated virus-DJ bound by a heparinoid pentasaccharide Q Xie, JM Spear, AJ Noble, DR Sousa, NL Meyer, O Davulcu, F Zhang, ... Molecular Therapy Methods & Clinical Development 5, 1-12, 2017 | 69 | 2017 |
| A pseudoatomic model of the COPII cage obtained from cryo-electron microscopy and mass spectrometry AJ Noble, Q Zhang, J O'donnell, H Hariri, N Bhattacharya, AG Marshall, ... Nature structural & molecular biology 20 (2), 167-173, 2013 | 67 | 2013 |
| Big data in cryoEM: automated collection, processing and accessibility of EM data PR Baldwin, YZ Tan, ET Eng, WJ Rice, AJ Noble, CJ Negro, ... Current opinion in microbiology 43, 1-8, 2018 | 66 | 2018 |
| Architecture of the human erythrocyte ankyrin-1 complex F Vallese, K Kim, LY Yen, JD Johnston, AJ Noble, T Calì, OB Clarke Nature structural & molecular biology 29 (7), 706-718, 2022 | 59 | 2022 |
| Insights into the mechanisms of membrane curvature and vesicle scission by the small GTPase Sar1 in the early secretory pathway H Hariri, N Bhattacharya, K Johnson, AJ Noble, SM Stagg Journal of molecular biology 426 (22), 3811-3826, 2014 | 59 | 2014 |
| Family-wide structural and biophysical analysis of binding interactions among non-clustered δ-protocadherins OJ Harrison, J Brasch, PS Katsamba, G Ahlsen, AJ Noble, H Dan, ... Cell reports 30 (8), 2655-2671. e7, 2020 | 45 | 2020 |
| The influence of frame alignment with dose compensation on the quality of single particle reconstructions JM Spear, AJ Noble, Q Xie, DR Sousa, MS Chapman, SM Stagg Journal of structural biology 192 (2), 196-203, 2015 | 35 | 2015 |
Edward T. EngSenior Scientist and Manager, New York Structural Biology CenterVerified email at nysbc.org