β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy C Soto, EM Sigurdsson, L Morelli, R Asok Kumar, EM Castaño, ... Nature medicine 4 (7), 822-826, 1998 | 1125 | 1998 |
Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. T Wisniewski, EM Castano, A Golabek, T Vogel, B Frangione The American journal of pathology 145 (5), 1030, 1994 | 635 | 1994 |
Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease AE Roher, CL Esh, TA Kokjohn, EM Castaño, GD Van Vickle, WM Kalback, ... Alzheimer's & Dementia 5 (1), 18-29, 2009 | 460 | 2009 |
The α-Helical to β-Strand Transition in the Amino-terminal Fragment of the Amyloid β-Peptide Modulates Amyloid Formation∗ C Soto, EM Castano, B Frangione, NC Inestrosa Journal of Biological Chemistry 270 (7), 3063-3067, 1995 | 428 | 1995 |
Differences between vascular and plaque core amyloid in Alzheimer's disease F Prelli, E Castano, GG Glenner, B Frangione Journal of neurochemistry 51 (2), 648-651, 1988 | 418 | 1988 |
Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease. SG Van Duinen, EM Castano, F Prelli, GT Bots, W Luyendijk, B Frangione Proceedings of the National Academy of Sciences 84 (16), 5991-5994, 1987 | 386 | 1987 |
Fibrillogenesis in Alzheimer's disease of amyloid β peptides and apolipoprotein E EM Castano, F Prelli, T Wisniewski, A Golabek, RA Kumar, C Soto, ... Biochemical Journal 306 (2), 599-604, 1995 | 354 | 1995 |
Degradation of soluble amyloid β-peptides 1–40, 1–42, and the Dutch variant 1–40Q by insulin degrading enzyme from Alzheimer disease and control brains A Pérez, L Morelli, JC Cresto, EM Castaño Neurochemical research 25, 247-255, 2000 | 317 | 2000 |
Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis. F Coria, E Castano, F Prelli, M Larrondo-Lillo, S Van Duinen, ... Laboratory investigation; a journal of technical methods and pathology 58 (4 …, 1988 | 308 | 1988 |
In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein EM Castaño, J Ghiso, F Prelli, PD Gorevic, A Migheli, B Frangione Biochemical and biophysical research communications 141 (2), 782-789, 1986 | 296 | 1986 |
Defective ubiquitination of cerebral proteins in Alzheimer's disease M López Salon, L Morelli, EM Castano, EF Soto, JM Pasquini Journal of neuroscience research 62 (2), 302-310, 2000 | 272 | 2000 |
Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects EM Castaño, AE Roher, CL Esh, TA Kokjohn, T Beach Neurological research 28 (2), 155-163, 2006 | 248 | 2006 |
Human amyloidosis Alzheimer's disease and related disorders. EM Castano Lab Invest 58, 122-132, 1988 | 242 | 1988 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 241 | 2021 |
Amyloid-β peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis RL Patton, WM Kalback, CL Esh, TA Kokjohn, GD Van Vickle, DC Luehrs, ... The American journal of pathology 169 (3), 1048-1063, 2006 | 228 | 2006 |
Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease W Kalback, C Esh, EM Castaño, A Rahman, T Kokjohn, DC Luehrs, L Sue, ... Neurological research 26 (5), 525-539, 2004 | 213 | 2004 |
Ten to fourteen residue peptides of Alzheimer's disease protein are sufficient for amyloid fibril formation and its characteristic Xray diffraction pattern PD Gorevic, EM Castano, R Sarma, B Frangione Biochemical and Biophysical Research Communications 147 (2), 854-862, 1987 | 204 | 1987 |
Fibrillogenesis of synthetic amyloid-β peptides is dependent on their initial secondary structure C Soto, EM Castaño, RA Kumar, RC Beavis, B Frangione Neuroscience letters 200 (2), 105-108, 1995 | 184 | 1995 |
Insulin-degrading enzyme sorting in exosomes: A secretory pathway for a key brain amyloid-β degrading protease A Bulloj, MC Leal, H Xu, EM Castaño, L Morelli Journal of Alzheimer's Disease 19 (1), 79-95, 2010 | 168 | 2010 |
Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein. F Coria, EM Castano, B Frangione The American journal of pathology 129 (3), 422, 1987 | 164 | 1987 |