Pooled CRISPR screening with single-cell transcriptome readout P Datlinger, AF Rendeiro, C Schmidl, T Krausgruber, P Traxler, ... Nature methods 14 (3), 297-301, 2017 | 1008 | 2017 |
High-content CRISPR screening C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ... Nature Reviews Methods Primers 2 (1), 1-23, 2022 | 487 | 2022 |
Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics M Farlik, NC Sheffield, A Nuzzo, P Datlinger, A Schönegger, ... Cell reports 10 (8), 1386-1397, 2015 | 482 | 2015 |
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space J Klughammer, B Kiesel, T Roetzer, N Fortelny, A Nemc, KH Nenning, ... Nature medicine 24 (10), 1611-1624, 2018 | 291 | 2018 |
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications Nature biotechnology 34 (7), 726-737, 2016 | 258 | 2016 |
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ... Nature medicine 23 (3), 386-395, 2017 | 245 | 2017 |
Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1 EM Tomazou, NC Sheffield, C Schmidl, M Schuster, A Schönegger, ... Cell reports 10 (7), 1082-1095, 2015 | 229 | 2015 |
Ultra-high-throughput single-cell RNA sequencing and perturbation screening with combinatorial fluidic indexing P Datlinger, AF Rendeiro, T Boenke, M Senekowitsch, T Krausgruber, ... Nature methods 18 (6), 635-642, 2021 | 194 | 2021 |
Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia G Heller, T Topakian, C Altenberger, S Cerny-Reiterer, S Herndlhofer, ... Leukemia 30 (9), 1861-1868, 2016 | 62 | 2016 |
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species J Klughammer, D Romanovskaia, A Nemc, A Posautz, CA Seid, ... Nature Communications 14 (1), 232, 2023 | 50 | 2023 |
Diagenode® Premium RRBS technology: cost-effective DNA methylation mapping with superior coverage AC Veillard, P Datlinger, M Laczik, S Squazzo, C Bock Nature Methods 13 (2), i-ii, 2016 | 36 | 2016 |
Differential DNA methylation analysis without a reference genome J Klughammer, P Datlinger, D Printz, NC Sheffield, M Farlik, J Hadler, ... Cell Reports 13 (11), 2621-2633, 2015 | 34 | 2015 |
Ultra-high throughput single-cell RNA sequencing by combinatorial fluidic indexing P Datlinger, AF Rendeiro, T Boenke, T Krausgruber, D Barreca, C Bock BioRxiv, 2019.12. 17.879304, 2019 | 32 | 2019 |
Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells J Ferreira da Silva, S Salic, M Wiedner, P Datlinger, P Essletzbichler, ... Scientific Reports 9 (1), 15751, 2019 | 21 | 2019 |
DNA methylation QTL analysis identifies new regulators of human longevity S Szymczak, J Dose, GG Torres, FA Heinsen, G Venkatesh, P Datlinger, ... Human molecular genetics 29 (7), 1154-1167, 2020 | 18 | 2020 |
Buffy coat signatures of breast cancer risk in a prospective cohort study FFL Chung, SG Maldonado, A Nemc, L Bouaoun, V Cahais, C Cuenin, ... Clinical epigenetics 15 (1), 102, 2023 | 7 | 2023 |
Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern TM Kulinski, MRT Casari, PM Guenzl, D Wenzel, D Andergassen, ... Developmental biology 402 (2), 291-305, 2015 | 7 | 2015 |
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening LUB Enk, M Hellmig, K Riecken, C Kilian, P Datlinger, SL Jauch-Speer, ... Science Immunology 9 (96), eadd6774, 2024 | 2 | 2024 |
Engineering Next-Generation CAR T Cells Via Genetic Screens P Datlinger, E Pankevich, CD Arnold, N Pranckevicius, J Lin, ... Blood 144, 7151, 2024 | | 2024 |
Method for sequencing rna oligonucleotides P Datlinger, C Bock US Patent App. 17/641,048, 2024 | | 2024 |