| Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9 MH Tatham, E Jaffray, OA Vaughan, JMP Desterro, CH Botting, ... Journal of Biological Chemistry 276 (38), 35368-35374, 2001 | 1048 | 2001 |
| RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation MH Tatham, MC Geoffroy, L Shen, A Plechanovova, N Hattersley, ... Nature cell biology 10 (5), 538-546, 2008 | 983 | 2008 |
| Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis A Plechanovová, EG Jaffray, MH Tatham, JH Naismith, RT Hay Nature 489 (7414), 115-120, 2012 | 607 | 2012 |
| System-wide changes to SUMO modifications in response to heat shock F Golebiowski, I Matic, MH Tatham, C Cole, Y Yin, A Nakamura, J Cox, ... Science signaling 2 (72), ra24-ra24, 2009 | 578 | 2009 |
| In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy I Matic, M van Hagen, J Schimmel, B Macek, SC Ogg, MH Tatham, ... Molecular & cellular proteomics 7 (1), 132-144, 2008 | 377 | 2008 |
| Proteome-wide identification of SUMO2 modification sites T Tammsalu, I Matic, EG Jaffray, AFM Ibrahim, MH Tatham, RT Hay Science signaling 7 (323), rs2-rs2, 2014 | 219 | 2014 |
| SUMO and transcriptional regulation DWH Girdwood, MH Tatham, RT Hay Seminars in cell & developmental biology 15 (2), 201-210, 2004 | 215 | 2004 |
| Purification and identification of endogenous polySUMO conjugates R Bruderer, MH Tatham, A Plechanovova, I Matic, AK Garg, RT Hay EMBO reports 12 (2), 142-148, 2011 | 213 | 2011 |
| Comparative proteomic analysis identifies a role for SUMO in protein quality control MH Tatham, I Matic, M Mann, RT Hay Science signaling 4 (178), rs4-rs4, 2011 | 194 | 2011 |
| SUMOylation of the GTPase Rac1 is required for optimal cell migration S Castillo-Lluva, MH Tatham, RC Jones, EG Jaffray, RD Edmondson, ... Nature cell biology 12 (11), 1078-1085, 2010 | 193 | 2010 |
| Detection of protein SUMOylation in vivo MH Tatham, MS Rodriguez, DP Xirodimas, RT Hay Nature protocols 4 (9), 1363-1371, 2009 | 192 | 2009 |
| Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection MH Tatham, S Kim, E Jaffray, J Song, Y Chen, RT Hay Nature structural & molecular biology 12 (1), 67-74, 2005 | 175 | 2005 |
| Identification of a substrate recognition site on Ubc9 D Lin, MH Tatham, B Yu, S Kim, RT Hay, Y Chen Journal of Biological Chemistry 277 (24), 21740-21748, 2002 | 157 | 2002 |
| SUMO protease SENP1 induces isomerization of the scissile peptide bond L Shen, MH Tatham, C Dong, A Zagórska, JH Naismith, RT Hay Nature structural & molecular biology 13 (12), 1069-1077, 2006 | 142 | 2006 |
| Role of an N-terminal site of Ubc9 in SUMO-1,-2, and-3 binding and conjugation MH Tatham, S Kim, B Yu, E Jaffray, J Song, J Zheng, MS Rodriguez, ... Biochemistry 42 (33), 9959-9969, 2003 | 127 | 2003 |
| Ube2W conjugates ubiquitin to α-amino groups of protein N-termini MH Tatham, A Plechanovová, EG Jaffray, H Salmen, RT Hay Biochemical Journal 453 (1), 137-145, 2013 | 123 | 2013 |
| Dss1 is a 26S proteasome ubiquitin receptor K Paraskevopoulos, F Kriegenburg, MH Tatham, HI Rösner, B Medina, ... Molecular cell 56 (3), 453-461, 2014 | 108 | 2014 |
| SUMO chain-induced dimerization activates RNF4 A Rojas-Fernandez, A Plechanovova, N Hattersley, E Jaffray, MH Tatham, ... Molecular cell 53 (6), 880-892, 2014 | 105 | 2014 |
| An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity N Schmidt, P Domingues, F Golebiowski, C Patzina, MH Tatham, RT Hay, ... Proceedings of the National Academy of Sciences 116 (35), 17399-17408, 2019 | 102 | 2019 |
| Global reprogramming of host SUMOylation during influenza virus infection P Domingues, F Golebiowski, MH Tatham, AM Lopes, A Taggart, RT Hay, ... Cell reports 13 (7), 1467-1480, 2015 | 97 | 2015 |
Hay RTProfessor of Molecular Biology, University of DundeeVerified email at dundee.ac.uk