Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities S Bhattacharyya, J Wei, J Varga Nature Reviews Rheumatology 8 (1), 42-54, 2012 | 449 | 2012 |
Myofibroblasts in murine cutaneous fibrosis originate from adiponectin‐positive intradermal progenitors RG Marangoni, BD Korman, J Wei, TA Wood, LV Graham, ML Whitfield, ... Arthritis & rheumatology 67 (4), 1062-1073, 2015 | 353 | 2015 |
Wnt/β‐catenin signaling is hyperactivated in systemic sclerosis and induces Smad‐dependent fibrotic responses in mesenchymal cells J Wei, F Fang, AP Lam, JL Sargent, E Hamburg, ME Hinchcliff, CJ Gottardi, ... Arthritis & Rheumatism 64 (8), 2734-2745, 2012 | 269 | 2012 |
Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? J Wei, D Melichian, K Komura, M Hinchcliff, AP Lam, R Lafyatis, ... Arthritis & Rheumatism 63 (6), 1707-1717, 2011 | 241 | 2011 |
Fibrosis in systemic sclerosis: emerging concepts and implications for targeted therapy J Wei, S Bhattacharyya, WG Tourtellotte, J Varga Autoimmunity reviews 10 (5), 267-275, 2011 | 226 | 2011 |
PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis J Wei, AK Ghosh, JL Sargent, K Komura, M Wu, QQ Huang, M Jain, ... PloS one 5 (11), e13778, 2010 | 219 | 2010 |
Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation AP Lam, AS Flozak, S Russell, J Wei, M Jain, GM Mutlu, GRS Budinger, ... American journal of respiratory cell and molecular biology 45 (5), 915-922, 2011 | 173 | 2011 |
Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator AK Ghosh, S Bhattacharyya, J Wei, S Kim, Y Barak, Y Mori, J Varga The FASEB Journal 23 (9), 2968, 2009 | 147 | 2009 |
The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy F Fang, L Liu, Y Yang, Z Tamaki, J Wei, RG Marangoni, S Bhattacharyya, ... Arthritis research & therapy 14 (5), 1-13, 2012 | 122 | 2012 |
Levels of adiponectin, a marker for PPAR-gamma activity, correlate with skin fibrosis in systemic sclerosis: potential utility as biomarker? K Lakota, J Wei, M Carns, M Hinchcliff, J Lee, ML Whitfield, S Sodin-Semrl, ... Arthritis research & therapy 14, 1-6, 2012 | 119 | 2012 |
Copper complex of hydroxyl-Substituted triazamacrocyclic ligand and its antitumor activity F Liang, C Wu, H Lin, T Li, D Gao, Z Li, J Wei, C Zheng, M Sun Bioorganic & medicinal chemistry letters 13 (15), 2469-2472, 2003 | 118 | 2003 |
p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis AK Ghosh, S Bhattacharyya, R Lafyatis, G Farina, J Yu, B Thimmapaya, ... Journal of Investigative Dermatology 133 (5), 1302-1310, 2013 | 113 | 2013 |
SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis K Akamata, J Wei, M Bhattacharyya, P Cheresh, MY Bonner, JL Arbiser, ... Oncotarget 7 (43), 69321, 2016 | 111 | 2016 |
The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates … F Fang, K Ooka, S Bhattachyya, J Wei, M Wu, P Du, S Lin, F Del Galdo, ... The American journal of pathology 178 (5), 2077-2090, 2011 | 104 | 2011 |
Delving into the minds of Chinese parents: What beliefs motivate their learning‐related practices? FFY Ng, J Wei Child Development Perspectives 14 (1), 61-67, 2020 | 102 | 2020 |
The histone deacetylase sirtuin 1 is reduced in systemic sclerosis and abrogates fibrotic responses by targeting transforming growth factor β signaling J Wei, AK Ghosh, H Chu, F Fang, ME Hinchcliff, J Wang, RG Marangoni, ... Arthritis & rheumatology 67 (5), 1323-1334, 2015 | 97 | 2015 |
Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target RG Marangoni, Y Masui, F Fang, B Korman, G Lord, J Lee, K Lakota, ... Scientific reports 7 (1), 4397, 2017 | 88 | 2017 |
A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses J Wei, H Zhu, K Komura, G Lord, M Tomcik, W Wang, S Doniparthi, ... Annals of the rheumatic diseases 73 (2), 446-454, 2014 | 85 | 2014 |
The JAK/STAT pathway is activated in systemic sclerosis and is effectively targeted by tofacitinib W Wang, S Bhattacharyya, RG Marangoni, M Carns, K Dennis-Aren, ... Journal of Scleroderma and Related Disorders 5 (1), 40-50, 2020 | 81 | 2020 |
Peroxisome proliferator-activated receptor γ: innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis J Wei, S Bhattacharyya, J Varga Current opinion in rheumatology 22 (6), 671-676, 2010 | 81 | 2010 |