Priming in the Type IF CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer C Richter, RL Dy, RE McKenzie, BNJ Watson, C Taylor, JT Chang, ... Nucleic acids research 42 (13), 8516-8526, 2014 | 230 | 2014 |
SdhE is a conserved protein required for flavinylation of succinate dehydrogenase in bacteria MB McNeil, JS Clulow, NM Wilf, GPC Salmond, PC Fineran Journal of Biological Chemistry 287 (22), 18418-18428, 2012 | 83 | 2012 |
PigS and PigP Regulate Prodigiosin Biosynthesis in Serratia via Differential Control of Divergent Operons, Which Include Predicted Transporters of Sulfur … T Gristwood, MB McNeil, JS Clulow, GPC Salmond, PC Fineran Journal of bacteriology 193 (5), 1076-1085, 2011 | 76 | 2011 |
Utilization of CRISPR Interference To Validate MmpL3 as a Drug Target in Mycobacterium tuberculosis MB McNeil, GM Cook Antimicrobial agents and chemotherapy 63 (8), 10.1128/aac. 00629-19, 2019 | 60 | 2019 |
MmpL3 inhibitors as antituberculosis drugs M Shao, M McNeil, GM Cook, X Lu European Journal of Medicinal Chemistry 200, 112390, 2020 | 50 | 2020 |
In Vitro Isolation and Characterization of Oxazolidinone-Resistant Mycobacterium tuberculosis MB McNeil, DD Dennison, CD Shelton, T Parish Antimicrobial Agents and Chemotherapy 61 (10), 10.1128/aac. 01296-17, 2017 | 45 | 2017 |
Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA Y Xia, Y Zhou, DS Carter, MB McNeil, W Choi, J Halladay, PW Berry, ... Life Science Alliance 1 (3), 2018 | 44 | 2018 |
The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis NJE Waller, CY Cheung, GM Cook, MB McNeil Nature Communications 14 (1), 1517, 2023 | 42 | 2023 |
The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria MB McNeil, HG Hampton, KJ Hards, BNJ Watson, GM Cook, PC Fineran FEBS letters 588 (3), 414-421, 2014 | 38 | 2014 |
Mutations in MmpL3 alter membrane potential, hydrophobicity and antibiotic susceptibility in Mycobacterium smegmatis MB McNeil, D Dennison, T Parish Microbiology 163 (7), 1065-1070, 2017 | 37 | 2017 |
CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis MB McNeil, LM Keighley, JR Cook, CY Cheung, GM Cook Molecular microbiology 116 (4), 1033-1043, 2021 | 35 | 2021 |
CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia HG Hampton, MB McNeil, TJ Paterson, B Ney, NR Williamson, ... Microbiology 162 (6), 1047-1058, 2016 | 33 | 2016 |
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents K Hards, C Adolph, LK Harold, MB McNeil, CY Cheung, A Jinich, ... Progress in biophysics and molecular biology 152, 35-44, 2020 | 31 | 2020 |
An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis K Hards, CY Cheung, N Waller, C Adolph, L Keighley, ZS Tee, LK Harold, ... Communications Biology 5 (1), 166, 2022 | 30 | 2022 |
Prokaryotic assembly factors for the attachment of flavin to complex II MB McNeil, PC Fineran Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 637-647, 2013 | 26 | 2013 |
Cell wall inhibitors increase the accumulation of rifampicin in Mycobacterium tuberculosis MB McNeil, S Chettiar, D Awasthi, T Parish Access Microbiology 1 (1), e000006, 2019 | 25 | 2019 |
Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and … PC Fineran, MC Iglesias Cans, JP Ramsay, NM Wilf, D Cossyleon, ... Genome announcements 1 (6), 10.1128/genomea. 01039-13, 2013 | 25 | 2013 |
The conserved RGxxE motif of the bacterial FAD assembly factor SdhE is required for succinate dehydrogenase flavinylation and activity MB McNeil, PC Fineran Biochemistry 52 (43), 7628-7640, 2013 | 24 | 2013 |
Transcriptional Inhibition of the F1F0-Type ATP Synthase Has Bactericidal Consequences on the Viability of Mycobacteria MB McNeil, HWK Ryburn, LK Harold, JF Tirados, GM Cook Antimicrobial agents and chemotherapy 64 (8), 10.1128/aac. 00492-20, 2020 | 22 | 2020 |
Multiple mutations in Mycobacterium tuberculosis MmpL3 increase resistance to MmpL3 inhibitors MB McNeil, T O’Malley, D Dennison, CD Shelton, B Sunde, T Parish Msphere 5 (5), 10.1128/msphere. 00985-20, 2020 | 20* | 2020 |