Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 4380 | 2016 |
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1182 | 2018 |
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Mei, S Wang, P Shah, PK Sorger elife, 2018 | 621 | 2018 |
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ... Cancer discovery 8 (2), 196-215, 2018 | 514 | 2018 |
A single-cell landscape of high-grade serous ovarian cancer B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ... Nature medicine 26 (8), 1271-1279, 2020 | 382 | 2020 |
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state M Fallahi‐Sichani, V Becker, B Izar, GJ Baker, JR Lin, SA Boswell, P Shah, ... Molecular systems biology 13 (1), 905, 2017 | 257 | 2017 |
Transcriptional mediators of treatment resistance in lethal prostate cancer MX He, MS Cuoco, J Crowdis, A Bosma-Moody, Z Zhang, K Bi, A Kanodia, ... Nature medicine 27 (3), 426-433, 2021 | 147 | 2021 |
Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization M Trivedi, M Talekar, P Shah, Q Ouyang, M Amiji Oncogenesis 5 (8), e250-e250, 2016 | 88 | 2016 |
Combination wt-p53 and MicroRNA-125b transfection in a genetically engineered lung cancer model using dual CD44/EGFR-targeting nanoparticles M Talekar, M Trivedi, P Shah, Q Ouyang, A Oka, S Gandham, MM Amiji Molecular Therapy 24 (4), 759-769, 2016 | 64 | 2016 |
Bidirectional cross talk between patient‐derived melanoma and cancer‐associated fibroblasts promotes invasion and proliferation B Izar, CE Joyce, S Goff, NL Cho, PM Shah, G Sharma, J Li, N Ibrahim, ... Pigment cell & melanoma research 29 (6), 656-668, 2016 | 41 | 2016 |
Long-chain acyl-CoA synthetase 1 role in sepsis and immunity: perspectives from a parallel review of public transcriptome datasets and of the literature J Roelands, M Garand, E Hinchcliff, Y Ma, P Shah, M Toufiq, M Alfaki, ... Frontiers in immunology 10, 2410, 2019 | 37 | 2019 |
MicroRNA-34a encapsulated in hyaluronic acid nanoparticles induces epigenetic changes with altered mitochondrial bioenergetics and apoptosis in non-small-cell lung cancer cells M Trivedi, A Singh, M Talekar, G Pawar, P Shah, M Amiji Scientific Reports 7 (1), 3636, 2017 | 33 | 2017 |
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity P Ho, JC Melms, M Rogava, CJ Frangieh, J Poźniak, SB Shah, Z Walsh, ... Cancer cell 41 (7), 1207-1221. e12, 2023 | 30 | 2023 |
Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes P Shah, MA Forget, ML Frank, P Jiang, D Sakellariou-Thompson, ... Journal for immunotherapy of cancer 10 (2), 2022 | 15 | 2022 |
Micronuclear collapse from oxidative damage M Di Bona, Y Chen, AS Agustinus, A Mazzagatti, MA Duran, M Deyell, ... Science 385 (6712), eadj8691, 2024 | 14 | 2024 |
Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens ZH Walsh, P Shah, N Kothapalli, SB Shah, G Nikolenyi, DZ Brodtman, ... Nature Biotechnology, 1-12, 2024 | 4 | 2024 |
A cancer cell program promotes T-cell exclusion and resistance to checkpoint blockade. P Shah, M Cuoco, MJ Su, J Melms, R Leeson, A Kanodia, S Mei, JR Lin, ... CANCER RESEARCH 80 (19), 43-43, 2020 | 3 | 2020 |
Widespread expression of GDNF throughout rat brain after intranasal delivery of hGDNF plasmid nanoparticles AEE Aly, BT Harmon, P Shah, O Sesenoglu-Laird, L Padegimas, ... CELL TRANSPLANTATION 24 (4), 752-753, 2015 | 3* | 2015 |
Single-cell RNA-sequencing and-imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade. B Izar, L Jerby-Arnon, A Rotem, P Shah, D Liu, G Zhang, B Schilling, ... Journal of Clinical Oncology 36 (15_suppl), 3074-3074, 2018 | 2 | 2018 |
Abstract AP19: single–cell rna–sequencing of patient–derived ovarian cancer cells and patient–derived xenograft models B Izar, E Stover, I Tirosh, A Rotem, P Shah, C Rodman, S Prakadan, ... Clinical Cancer Research 23 (11_Supplement), AP19-AP19, 2017 | 2 | 2017 |