F1F0 ATP synthase subunit c is a substrate of the novel YidC pathway for membrane protein biogenesis M van der Laan, P Bechtluft, S Kol, N Nouwen, AJM Driessen The Journal of cell biology 165 (2), 213-222, 2004 | 299 | 2004 |
Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2) M Gottelt, S Kol, JP Gomez-Escribano, M Bibb, E Takano Microbiology 156 (8), 2343-2353, 2010 | 198 | 2010 |
One‐step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment LM Grav, JS Lee, S Gerling, TB Kallehauge, AH Hansen, S Kol, GM Lee, ... Biotechnology journal 10 (9), 1446-1456, 2015 | 164 | 2015 |
Evolution-guided engineering of small-molecule biosensors T Snoek, EK Chaberski, F Ambri, S Kol, SP Bjørn, B Pang, JF Barajas, ... Nucleic acids research 48 (1), e3-e3, 2020 | 136 | 2020 |
Multiplex secretome engineering enhances recombinant protein production and purity S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ... Nature communications 11 (1), 1-10, 2020 | 104 | 2020 |
Metabolomic Characterization of the Salt Stress Response in Streptomyces coelicolor S Kol, ME Merlo, RA Scheltema, M De Vries, RJ Vonk, NA Kikkert, ... Applied and environmental microbiology 76 (8), 2574-2581, 2010 | 103 | 2010 |
Mechanisms of YidC-mediated insertion and assembly of multimeric membrane protein complexes S Kol, N Nouwen, AJM Driessen Journal of Biological Chemistry 283 (46), 31269-31273, 2008 | 88 | 2008 |
Discovery and characterization of Cas9 inhibitors disseminated across seven bacterial phyla RV Uribe, E van der Helm, MA Misiakou, SW Lee, S Kol, MOA Sommer Cell host & microbe 25 (2), 233-241. e5, 2019 | 87 | 2019 |
The oligomeric distribution of SecYEG is altered by SecA and translocation ligands J Scheuring, N Braun, L Nothdurft, M Stumpf, AKJ Veenendaal, S Kol, ... Journal of molecular biology 354 (2), 258-271, 2005 | 75 | 2005 |
Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence MC Martos-Maldonado, CT Hjuler, KK Sørensen, MB Thygesen, ... Nature communications 9 (1), 3307, 2018 | 68 | 2018 |
Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles T Amann, AH Hansen, S Kol, HG Hansen, J Arnsdorf, S Nallapareddy, ... Metabolic Engineering 52, 143-152, 2019 | 64 | 2019 |
Subunit a of the F1F0 ATP synthase requires YidC and SecYEG for membrane insertion S Kol, W Majczak, R Heerlien, JP van der Berg, N Nouwen, AJM Driessen Journal of molecular biology 390 (5), 893-901, 2009 | 57 | 2009 |
YidC-mediated membrane insertion of assembly mutants of subunit c of the F1F0 ATPase S Kol, BR Turrell, J de Keyzer, M van der Laan, N Nouwen, AJM Driessen Journal of Biological Chemistry 281 (40), 29762-29768, 2006 | 45 | 2006 |
Predictive glycoengineering of biosimilars using a Markov chain glycosylation model PN Spahn, AH Hansen, S Kol, BG Voldborg, NE Lewis Biotechnology journal 12 (2), 1600489, 2017 | 43 | 2017 |
Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells HG Hansen, CN Nilsson, AM Lund, S Kol, LM Grav, M Lundqvist, ... Scientific reports 5 (1), 18016, 2015 | 40 | 2015 |
Baicalein reduces oxidative stress in CHO cell cultures and improves recombinant antibody productivity TK Ha, AH Hansen, S Kol, HF Kildegaard, GM Lee Biotechnology Journal 13 (3), 1700425, 2018 | 38 | 2018 |
CRISPR/Cas9‐Multiplexed Editing of Chinese Hamster Ovary B4Gal‐T1, 2, 3, and 4 Tailors N‐Glycan Profiles of Therapeutics and Secreted Host Cell Proteins T Amann, AH Hansen, S Kol, GM Lee, MR Andersen, HF Kildegaard Biotechnology journal 13 (10), 1800111, 2018 | 34 | 2018 |
In vitro synthesis and oligomerization of the mechanosensitive channel of large conductance, MscL, into a functional ion channel CE Price, A Kocer, S Kol, JP van der Berg, AJM Driessen FEBS letters 585 (1), 249-254, 2011 | 34 | 2011 |
Development of a VHH-Based Erythropoietin Quantification Assay S Kol, TB Kallehauge, S Adema, P Hermans Molecular biotechnology 57, 692-700, 2015 | 20 | 2015 |
Heterologous expression and purification of an active human TRPV 3 ion channel S Kol, C Braun, G Thiel, DA Doyle, M Sundström, P Gourdon, P Nissen The FEBS journal 280 (23), 6010-6021, 2013 | 13 | 2013 |