| In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector L Naldini, U Blömer, P Gallay, D Ory, R Mulligan, FH Gage, IM Verma, ... Science 272 (5259), 263-267, 1996 | 6693 | 1996 |
| Triglyceride accumulation protects against fatty acid-induced lipotoxicity LL Listenberger, X Han, SE Lewis, S Cases, RV Farese Jr, DS Ory, ... Proceedings of the National Academy of Sciences 100 (6), 3077-3082, 2003 | 2290 | 2003 |
| A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. DS Ory, BA Neugeboren, RC Mulligan Proceedings of the National Academy of Sciences 93 (21), 11400-11406, 1996 | 1143 | 1996 |
| Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection M Côté, J Misasi, T Ren, A Bruchez, K Lee, CM Filone, L Hensley, Q Li, ... Nature 477 (7364), 344-348, 2011 | 839 | 2011 |
| Palmitate-induced apoptosis can occur through a ceramide-independent pathway LL Listenberger, DS Ory, JE Schaffer Journal of Biological Chemistry 276 (18), 14890-14895, 2001 | 730 | 2001 |
| Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death NM Borradaile, X Han, JD Harp, SE Gale, DS Ory, JE Schaffer Journal of lipid research 47 (12), 2726-2737, 2006 | 691 | 2006 |
| miR-33 links SREBP-2 induction to repression of sterol transporters TJ Marquart, RM Allen, DS Ory, Á Baldán Proceedings of the national academy of sciences 107 (27), 12228-12232, 2010 | 675 | 2010 |
| Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy HC Chiu, A Kovacs, RM Blanton, X Han, M Courtois, CJ Weinheimer, ... Circulation research 96 (2), 225-233, 2005 | 549 | 2005 |
| Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression CD Davidson, NF Ali, MC Micsenyi, G Stephney, S Renault, K Dobrenis, ... PloS one 4 (9), e6951, 2009 | 536 | 2009 |
| Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ... Science 355 (6331), 1306-1311, 2017 | 515 | 2017 |
| Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells CF Lai, L Chaudhary, A Fausto, LR Halstead, DS Ory, LV Avioli, ... Journal of Biological Chemistry 276 (17), 14443-14450, 2001 | 505 | 2001 |
| Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease FD Porter, DE Scherrer, MH Lanier, SJ Langmade, V Molugu, SE Gale, ... Science translational medicine 2 (56), 56ra81-56ra81, 2010 | 405 | 2010 |
| Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial DS Ory, EA Ottinger, NY Farhat, KA King, X Jiang, L Weissfeld, ... The Lancet 390 (10104), 1758-1768, 2017 | 337 | 2017 |
| A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma [S] X Jiang, R Sidhu, FD Porter, NM Yanjanin, AO Speak, DT Te Vruchte, ... Journal of lipid research 52 (7), 1435-1445, 2011 | 313 | 2011 |
| Consensus clinical management guidelines for Niemann-Pick disease type C T Geberhiwot, A Moro, A Dardis, U Ramaswami, S Sirrs, MP Marfa, ... Orphanet journal of rare diseases 13, 1-19, 2018 | 298 | 2018 |
| Fatty acid synthesis configures the plasma membrane for inflammation in diabetes X Wei, H Song, L Yin, MG Rizzo, R Sidhu, DF Covey, DS Ory, ... Nature 539 (7628), 294-298, 2016 | 297 | 2016 |
| ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C CY Lim, OB Davis, HR Shin, J Zhang, CA Berdan, X Jiang, JL Counihan, ... Nature cell biology 21 (10), 1206-1218, 2019 | 276 | 2019 |
| Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress CI Michel, CL Holley, BS Scruggs, R Sidhu, RT Brookheart, ... Cell metabolism 14 (1), 33-44, 2011 | 271 | 2011 |
| NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols A Frolov, SE Zielinski, JR Crowley, N Dudley-Rucker, JE Schaffer, DS Ory Journal of Biological Chemistry 278 (28), 25517-25525, 2003 | 271 | 2003 |
| Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration A Sene, AA Khan, D Cox, REI Nakamura, A Santeford, BM Kim, R Sidhu, ... Cell metabolism 17 (4), 549-561, 2013 | 270 | 2013 |
