Articles with public access mandates - Daniel OryLearn more
Available somewhere: 138
Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
M Côté, J Misasi, T Ren, A Bruchez, K Lee, CM Filone, L Hensley, Q Li, ...
Nature 477 (7364), 344-348, 2011
Mandates: US National Institutes of Health, Fonds de recherche du Québec - Santé
miR-33 links SREBP-2 induction to repression of sterol transporters
TJ Marquart, RM Allen, DS Ory, Á Baldán
Proceedings of the national academy of sciences 107 (27), 12228-12232, 2010
Mandates: US National Institutes of Health
Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression
CD Davidson, NF Ali, MC Micsenyi, G Stephney, S Renault, K Dobrenis, ...
PloS one 4 (9), e6951, 2009
Mandates: US National Institutes of Health
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
BM Castellano, AM Thelen, O Moldavski, MK Feltes, REN Van Der Welle, ...
Science 355 (6331), 1306-1311, 2017
Mandates: US National Science Foundation, US National Institutes of Health, Howard …
Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease
FD Porter, DE Scherrer, MH Lanier, SJ Langmade, V Molugu, SE Gale, ...
Science translational medicine 2 (56), 56ra81-56ra81, 2010
Mandates: US National Institutes of Health
Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1–2 trial
DS Ory, EA Ottinger, NY Farhat, KA King, X Jiang, L Weissfeld, ...
The Lancet 390 (10104), 1758-1768, 2017
Mandates: US National Institutes of Health
A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma [S]
X Jiang, R Sidhu, FD Porter, NM Yanjanin, AO Speak, DT Te Vruchte, ...
Journal of lipid research 52 (7), 1435-1445, 2011
Mandates: US National Institutes of Health
Fatty acid synthesis configures the plasma membrane for inflammation in diabetes
X Wei, H Song, L Yin, MG Rizzo, R Sidhu, DF Covey, DS Ory, ...
Nature 539 (7628), 294-298, 2016
Mandates: US National Institutes of Health
ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C
CY Lim, OB Davis, HR Shin, J Zhang, CA Berdan, X Jiang, JL Counihan, ...
Nature cell biology 21 (10), 1206-1218, 2019
Mandates: US National Institutes of Health, American Heart Association
Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress
CI Michel, CL Holley, BS Scruggs, R Sidhu, RT Brookheart, ...
Cell metabolism 14 (1), 33-44, 2011
Mandates: US National Institutes of Health
Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration
A Sene, AA Khan, D Cox, REI Nakamura, A Santeford, BM Kim, R Sidhu, ...
Cell metabolism 17 (4), 549-561, 2013
Mandates: US National Institutes of Health
A new glucocerebrosidase chaperone reduces α-synuclein and glycolipid levels in iPSC-derived dopaminergic neurons from patients with Gaucher disease and parkinsonism
E Aflaki, DK Borger, N Moaven, BK Stubblefield, SA Rogers, S Patnaik, ...
Journal of Neuroscience 36 (28), 7441-7452, 2016
Mandates: US National Institutes of Health
Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease
CH Vite, JH Bagel, GP Swain, M Prociuk, TU Sikora, VM Stein, ...
Science translational medicine 7 (276), 276ra26-276ra26, 2015
Mandates: US National Institutes of Health, German Research Foundation
High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets
CA Wassif, JL Cross, J Iben, L Sanchez-Pulido, A Cougnoux, FM Platt, ...
Genetics in Medicine 18 (1), 41-48, 2016
Mandates: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
Recommendations for the detection and diagnosis of Niemann-Pick disease type C: An update
MC Patterson, P Clayton, P Gissen, M Anheim, P Bauer, O Bonnot, ...
Neurology: Clinical Practice 7 (6), 499-511, 2017
Mandates: US National Institutes of Health
Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages
JD Schilling, HM Machkovech, L He, R Sidhu, H Fujiwara, K Weber, ...
Journal of Biological Chemistry 288 (5), 2923-2932, 2013
Mandates: US National Institutes of Health
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders
M Xu, K Liu, M Swaroop, FD Porter, R Sidhu, S Finkes, DS Ory, ...
Journal of Biological Chemistry 287 (47), 39349-39360, 2012
Mandates: US National Institutes of Health
Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking
JR Zhang, T Coleman, SJ Langmade, DE Scherrer, L Lane, MH Lanier, ...
The Journal of clinical investigation 118 (6), 2281-2290, 2008
Mandates: US National Institutes of Health
Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease
E A. Ottinger, M L. Kao, N Carrillo-Carrasco, N Yanjanin, ...
Current topics in medicinal chemistry 14 (3), 330-339, 2014
Mandates: US National Institutes of Health
Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes
RP Bowler, S Jacobson, C Cruickshank, GJ Hughes, C Siska, DS Ory, ...
American journal of respiratory and critical care medicine 191 (3), 275-284, 2015
Mandates: US National Institutes of Health
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