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Tom Macleod
Tom Macleod
Verified email at leeds.ac.uk
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Cited by
Cited by
Year
Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ
JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, ...
Proceedings of the national academy of sciences 114 (13), E2748-E2757, 2017
1632017
Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist
T Macleod, R Doble, D McGonagle, CW Wasson, A Alase, M Stacey, ...
Scientific reports 6 (1), 24880, 2016
1042016
IL-36γ is a strong inducer of IL-23 in psoriatic cells and activates angiogenesis
C Bridgewood, GW Fearnley, A Berekmeri, P Laws, T Macleod, ...
Frontiers in immunology 9, 200, 2018
932018
T helper 2 IL-4/IL-13 dual blockade with dupilumab is linked to some emergent T helper 17‒type diseases, including seronegative arthritis and enthesitis/enthesopathy, but not …
C Bridgewood, M Wittmann, T Macleod, A Watad, D Newton, K Bhan, ...
Journal of Investigative Dermatology 142 (10), 2660-2667, 2022
812022
The immunological impact of IL-1 family cytokines on the epidermal barrier
T Macleod, A Berekmeri, C Bridgewood, M Stacey, D McGonagle, ...
Frontiers in Immunology 12, 808012, 2021
572021
The proinflammatory cytokine IL-36γ is a global discriminator of harmless microbes and invasive pathogens within epithelial tissues
T Macleod, JS Ainscough, C Hesse, S Konzok, A Braun, AL Buhl, ...
Cell Reports 33 (11), 2020
382020
Detection of IL-36γ through noninvasive tape stripping reliably discriminates psoriasis from atopic eczema
A Berekméri, A Latzko, A Alase, T Macleod, JS Ainscough, P Laws, ...
Journal of Allergy and Clinical Immunology 142 (3), 988-991. e4, 2018
342018
Antimicrobial peptide LL-37 facilitates intracellular uptake of RNA aptamer Apt 21-2 without inducing an inflammatory or interferon response
T Macleod, J Ward, AA Alase, C Bridgewood, M Wittmann, ...
Frontiers in immunology 10, 857, 2019
222019
Predominant ligament-centric soft-tissue involvement differentiates axial psoriatic arthritis from ankylosing spondylitis
D McGonagle, P David, T Macleod, A Watad
Nature Reviews Rheumatology 19 (12), 818-827, 2023
182023
Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in inflammatory arthritis: a narrative of the emergence of MAPK-Activated Protein kinase inhibitors (MK2i)
P Ganguly, T Macleod, C Wong, M Harland, D McGonagle
Pharmaceuticals 16 (9), 1286, 2023
182023
Role of neutrophil interleukin-23 in spondyloarthropathy spectrum disorders
T Macleod, C Bridgewood, D McGonagle
The Lancet Rheumatology 5 (1), e47-e57, 2023
162023
What is COVID-19?
J David, O Hen, N Ben-Shabbat, T Macleod, H Amital, A Watad, ...
MD, FAAP, FACP, AAHIVS Assistant Professor of Medicine and Pediatrics, Adult …, 2021
72021
Molecular and cellular regulation of psoriatic inflammation
T Macleod, C Bridgewood, I Hyde, M Heague, P Helliwell, M Stacey, ...
Clinical Science 136 (12), 935-952, 2022
62022
How underappreciated autoinflammatory (innate immunity) mechanisms dominate disparate autoimmune disorders
K Abacar, T Macleod, H Direskeneli, D McGonagle
Frontiers in Immunology 15, 1439371, 2024
22024
Anti-IL-5 biologics and rheumatoid arthritis: a single-centre 500 patient year exposure analysis
NJ Dean, IJ Clifton, R Salman, C Bridgewood, J Nam, T Macleod, ...
RMD open 9 (4), e003583, 2023
22023
AB0011 CYTOMETRIC ANALYSIS OF ACTIVATED ENTHESEAL TISSUE RESIDENT T-CELLS REVEALS IL-17F AS THE DOMINANT IL-17 ISOFORM EXPRESSED BY INNATE AND ADAPTIVE LYMPHOCYTES
N Mcdermott, T Macleod, AS Rao, V Borse, P Loughenbury, R Dunsmuir, ...
Annals of the Rheumatic Diseases 82 (Suppl 1), 1184-1185, 2023
22023
POS0331 UPADACITINIB EFFECTIVELY LIMITS IL-23 DRIVEN INFLAMMATION AT THE ENTHESIS BY INHIBITING T CELL STAT1 PHOSPHORYLATION, IL-17A AND TNFα PRODUCTION
S Giryes, C Bridgewood, C Wong, T Macleod, D Mcgonagle
Annals of the Rheumatic Diseases 81 (Suppl 1), 418-418, 2022
12022
Takayasu arteritis: a geographically distant but immunologically proximal MHC-I-opathy
K Abacar, T Macleod, H Direskeneli, D McGonagle
The Lancet Rheumatology, 2025
2025
Epidermal proteomics demonstrates Elafin as a psoriasis‐specific biomarker and highlights increased anti‐inflammatory activity around psoriatic plaques
A Berekmeri, T Macleod, I Hyde, GJ Ojak, C Mann, D Kramer, M Stacey, ...
Journal of the European Academy of Dermatology and Venereology, 2024
2024
OP0244 INVESTIGATION OF NORMAL ENTHESIS IL-17F CELL SUBSETS, PROTEIN EXPRESSION AND ITS IMPACT ON ENTHESEAL MESENCHYMAL STEM CELL FUNCTION
N Mcdermott, M Harland, C Wong, A Altaie, T Macleod, C Bridgewood, ...
Annals of the Rheumatic Diseases 83 (Suppl 1), 109-110, 2024
2024
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