A matrix metalloproteinase expressed on the surface of invasive tumour cells H Sato, T Takino, Y Okada, J Cao, A Shinagawa, E Yamamoto, M Seiki Nature 370 (6484), 61-65, 1994 | 3274 | 1994 |
Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. M Seiki, S Hattori, Y Hirayama, M Yoshida Proceedings of the national academy of sciences 80 (12), 3618-3622, 1983 | 1953 | 1983 |
SRα promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus … Y Takebe, M Seiki, JI Fujisawa, P Hoy, K Yokota, KI Arai, M Yoshida, ... Molecular and cellular biology 8 (1), 466-472, 1988 | 1815 | 1988 |
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules E Ohuchi, K Imai, Y Fujii, H Sato, M Seiki, Y Okada Journal of Biological Chemistry 272 (4), 2446-2451, 1997 | 1224 | 1997 |
Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease. M Yoshida, M Seiki, K Yamaguchi, K Takatsuki Proceedings of the National Academy of Sciences 81 (8), 2534-2537, 1984 | 1081 | 1984 |
Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration M Kajita, Y Itoh, T Chiba, H Mori, A Okada, H Kinoh, M Seiki The Journal of cell biology 153 (5), 893-904, 2001 | 950 | 2001 |
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis J Oh, R Takahashi, S Kondo, A Mizoguchi, E Adachi, RM Sasahara, ... Cell 107 (6), 789-800, 2001 | 940 | 2001 |
Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. H Sato, M Seiki Oncogene 8 (2), 395-405, 1993 | 874 | 1993 |
Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library: MT-MMPs form a unique membrane-type subclass in the MMP … T Takino, H Sato, A Shinagawa, M Seiki Journal of Biological Chemistry 270 (39), 23013-23020, 1995 | 618 | 1995 |
Induction of interleukin 2 receptor gene expression by p40x encoded by human T‐cell leukemia virus type 1. JL Inoue, M Seiki, T Taniguchi, S Tsuru, M Yoshida The EMBO Journal 5 (11), 2883-2888, 1986 | 602 | 1986 |
MT1‐MMP: a potent modifier of pericellular microenvironment Y Itoh, M Seiki Journal of cellular physiology 206 (1), 1-8, 2006 | 584 | 2006 |
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion H Nakahara, L Howard, EW Thompson, H Sato, M Seiki, Y Yeh, WT Chen Proceedings of the National Academy of Sciences 94 (15), 7959-7964, 1997 | 541 | 1997 |
Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion M Seiki Cancer letters 194 (1), 1-11, 2003 | 525 | 2003 |
Homophilic complex formation of MT1‐MMP facilitates proMMP‐2 activation on the cell surface and promotes tumor cell invasion Y Itoh, A Takamura, N Ito, Y Maru, H Sato, N Suenaga, T Aoki, M Seiki The EMBO journal, 2001 | 510 | 2001 |
Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering M Maruyama, H Shibuya, H Harada, M Hatakeyama, M Seiki, T Fujita, ... Cell 48 (2), 343-350, 1987 | 504 | 1987 |
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis S Hiratsuka, Y Maru, A Okada, M Seiki, T Noda, M Shibuya Cancer research 61 (3), 1207-1213, 2001 | 494 | 2001 |
Activation of a recombinant membrane type 1‐matrix metalloproteinase (MT1‐MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)‐2 H Sato, T Kinoshita, T Takino, K Nakayama, M Seiki FEBS letters 393 (1), 101-104, 1996 | 494 | 1996 |
Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites … R Gum, E Lengyel, J Juarez, JH Chen, H Sato, M Seiki, D Boyd Journal of Biological Chemistry 271 (18), 10672-10680, 1996 | 425 | 1996 |
CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain H Mori, T Tomari, N Koshikawa, M Kajita, Y Itoh, H Sato, H Tojo, I Yana, ... The EMBO journal 21 (15), 3949-3959, 2002 | 421 | 2002 |
Expression of membrane-type matrix metalloproteinase in human gastric carcinomas H Nomura, H Sato, M Seiki, M Mai, Y Okada Cancer Research 55 (15), 3263-3266, 1995 | 418 | 1995 |