Selection bias at the heterosexual HIV-1 transmission bottleneck JM Carlson, M Schaefer, DC Monaco, R Batorsky, DT Claiborne, J Prince, ... Science 345 (6193), 1254031, 2014 | 298 | 2014 |
Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression DT Claiborne, JL Prince, E Scully, G Macharia, L Micci, B Lawson, ... Proceedings of the National Academy of Sciences 112 (12), E1480-E1489, 2015 | 129 | 2015 |
Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis JL Prince, DT Claiborne, JM Carlson, M Schaefer, T Yu, S Lahki, ... PLoS pathogens 8 (11), e1003041, 2012 | 113 | 2012 |
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo CR Maldini, DT Claiborne, K Okawa, T Chen, DL Dopkin, X Shan, ... Nature medicine 26 (11), 1776-1787, 2020 | 102 | 2020 |
Impact of HLA-B* 81-associated mutations in HIV-1 Gag on viral replication capacity JK Wright, VL Naidoo, ZL Brumme, JL Prince, DT Claiborne, PJR Goulder, ... Journal of virology 86 (6), 3193-3199, 2012 | 79 | 2012 |
Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity SJ Bhakta, L Shang, JL Prince, DT Claiborne, E Hunter Retrovirology 8, 1-17, 2011 | 63 | 2011 |
Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients L Yue, KJ Pfafferott, J Baalwa, K Conrod, CC Dong, C Chui, R Rong, ... PLoS pathogens 11 (1), e1004565, 2015 | 59 | 2015 |
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer KD Miller, S O’Connor, KA Pniewski, T Kannan, R Acosta, G Mirji, S Papp, ... Nature Cancer 4 (10), 1491-1507, 2023 | 49 | 2023 |
HIV-1 variants are archived throughout infection and persist in the reservoir K Brooks, BR Jones, DA Dilernia, DJ Wilkins, DT Claiborne, S McInally, ... PLoS pathogens 16 (6), e1008378, 2020 | 47 | 2020 |
Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression DC Mónaco, DA Dilernia, A Fiore-Gartland, T Yu, JL Prince, KK Dennis, ... Journal of Experimental Medicine 213 (10), 2049-2063, 2016 | 39 | 2016 |
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis W Zhou, H Liu, Z Yuan, J Zundell, M Towers, J Lin, S Lombardi, H Nie, ... Cancer Cell 41 (4), 740-756. e10, 2023 | 38 | 2023 |
Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased … MJ Deymier, DT Claiborne, Z Ende, HK Ratner, W Kilembe, S Allen, ... Virology 468, 454-461, 2014 | 30 | 2014 |
Immunization of BLT humanized mice redirects T cell responses to Gag and reduces acute HIV-1 viremia DT Claiborne, TE Dudek, CR Maldini, KA Power, M Ghebremichael, ... Journal of virology 93 (20), 10.1128/jvi. 00814-19, 2019 | 25 | 2019 |
Innate immune reconstitution in humanized bone marrow-liver-thymus (HuBLT) mice governs adaptive cellular immune function and responses to HIV-1 infection WF Garcia-Beltran, DT Claiborne, CR Maldini, M Phelps, V Vrbanac, ... Frontiers in Immunology 12, 667393, 2021 | 19 | 2021 |
A restriction enzyme based cloning method to assess the in vitro replication capacity of HIV-1 subtype C Gag-MJ4 chimeric viruses DT Claiborne, JL Prince, E Hunter Journal of visualized experiments: JoVE, 51506, 2014 | 17 | 2014 |
Poly I:C and STING agonist‐primed DC increase lymphoid tissue polyfunctional HIV‐1‐specific CD8+ T cells and limit CD4+ T‐cell loss in BLT mice M Calvet‐Mirabent, DT Claiborne, M Deruaz, S Tanno, C Serra, ... European journal of immunology 52 (3), 447-461, 2022 | 16 | 2022 |
Better Viral Control despite Higher CD4+ T Cell Activation during Acute HIV-1 Infection in Zambian Women Is Linked to the Sex Hormone Estradiol E El-Badry, G Macharia, D Claiborne, K Brooks, DA Dilernia, P Goepfert, ... Journal of Virology 94 (16), 10.1128/jvi. 00758-20, 2020 | 16 | 2020 |
Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency KA Sutherland, DA Collier, DT Claiborne, JL Prince, MJ Deymier, ... Scientific reports 6 (1), 38153, 2016 | 16 | 2016 |
HLA class I downregulation by HIV-1 variants from subtype C transmission pairs Z Ende, MJ Deymier, DT Claiborne, JL Prince, DC Monaco, W Kilembe, ... Journal of virology 92 (7), 10.1128/jvi. 01633-17, 2018 | 15 | 2018 |
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression A Indeglia, JC Leung, SA Miller, JIJ Leu, JF Dougherty, NL Clarke, ... Cancer discovery 13 (7), 1696-1719, 2023 | 14 | 2023 |