| Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial MG Kaplitt, A Feigin, C Tang, HL Fitzsimons, P Mattis, PA Lawlor, ... The Lancet 369 (9579), 2097-2105, 2007 | 1341 | 2007 |
| Glucagon-like peptide-1 receptor is involved in learning and neuroprotection MJ During, L Cao, DS Zuzga, JS Francis, HL Fitzsimons, X Jiao, RJ Bland, ... Nature medicine 9 (9), 1173-1179, 2003 | 1003 | 2003 |
| Subthalamic GAD gene therapy in a Parkinson's disease rat model J Luo, MG Kaplitt, HL Fitzsimons, DS Zuzga, Y Liu, ML Oshinsky, ... Science 298 (5592), 425-429, 2002 | 382 | 2002 |
| An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy MJ During, CW Symes, PA Lawlor, J Lin, J Dunning, HL Fitzsimons, ... Science 287 (5457), 1453-1460, 2000 | 331 | 2000 |
| Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes. R Xu, CG Janson, M Mastakov, P Lawlor, D Young, A Mouravlev, ... Gene therapy 8 (17), 1323-1332, 2001 | 240 | 2001 |
| AAV Vector–mediated RNAi of Mutant Huntingtin Expression Is Neuroprotective in a Novel Genetic Rat Model of Huntington's Disease NR Franich, HL Fitzsimons, DM Fong, M Klugmann, MJ During, D Young Molecular Therapy 16 (5), 947-956, 2008 | 202 | 2008 |
| Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism ME Emborg, M Carbon, JE Holden, MJ During, Y Ma, C Tang, J Moirano, ... Journal of Cerebral Blood Flow & Metabolism 27 (3), 501-509, 2007 | 154 | 2007 |
| Combined injection of rAAV with mannitol enhances gene expression in the rat brain MY Mastakov, K Baer, R Xu, H Fitzsimons, MJ During Molecular therapy 3 (2), 225-232, 2001 | 136 | 2001 |
| Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain HL Fitzsimons, RJ Bland, MJ During Methods 28 (2), 227-236, 2002 | 125 | 2002 |
| The histone deacetylase HDAC4 regulates long-term memory in Drosophila HL Fitzsimons, S Schwartz, FM Given, MJ Scott PloS one 8 (12), e83903, 2013 | 87 | 2013 |
| Anticonvulsant effects and behavioural outcomes of rAAV serotype 1 vector-mediated neuropeptide Y overexpression in rat hippocampus F Noe, V Vaghi, C Balducci, H Fitzsimons, R Bland, D Zardoni, G Sperk, ... Gene therapy 17 (5), 643-652, 2010 | 80 | 2010 |
| Gene therapy in epilepsy V Riban, HL Fitzsimons, MJ During Epilepsia 50 (1), 24-32, 2009 | 72 | 2009 |
| Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain. HL Fitzsimons, JM McKenzie, MJ During Gene therapy 8 (22), 1675-1681, 2001 | 72 | 2001 |
| Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor RJ Linger, EJ Belikoff, Y Yan, F Li, HA Wantuch, HL Fitzsimons, MJ Scott BMC biotechnology 16 (1), 1-12, 2016 | 65 | 2016 |
| Genetic modulation of Rpd3 expression impairs long-term courtship memory in Drosophila HL Fitzsimons, MJ Scott PloS ONE 6 (12), 2011 | 55 | 2011 |
| The Class IIa histone deacetylase HDAC4 and neuronal function: Nuclear nuisance and cytoplasmic stalwart? HL Fitzsimons Neurobiology of learning and memory 123, 149-158, 2015 | 47 | 2015 |
| Neuropeptide Y overexpression using recombinant adenoassociated viral vectors F Noé, A Frasca, C Balducci, M Carli, G Sperk, F Ferraguti, A Pitkänen, ... Neurotherapeutics 6, 300-306, 2009 | 46 | 2009 |
| Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9 S Schwartz, M Truglio, MJ Scott, HL Fitzsimons Genetics 203 (3), 1249-1264, 2016 | 41 | 2016 |
| The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila PS Freymuth, HL Fitzsimons Molecular Brain 10 (1), 41, 2017 | 36 | 2017 |
| HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity AE Jung, HL Fitzsimons, RJ Bland, MJ During, D Young Molecular Therapy 16 (6), 1048-1055, 2008 | 35 | 2008 |
