mtDNA activates cGAS signaling and suppresses the YAP-mediated endothelial cell proliferation program to promote inflammatory injury LS Huang, Z Hong, W Wu, S Xiong, M Zhong, X Gao, J Rehman, AB Malik Immunity 52 (3), 475-486. e5, 2020 | 317 | 2020 |
IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury S Xiong, Z Hong, LS Huang, Y Tsukasaki, S Nepal, A Di, M Zhong, W Wu, ... The Journal of clinical investigation 130 (7), 3684-3698, 2020 | 174 | 2020 |
Sphingosine-1–phosphate, FTY720, and Sphingosine-1–phosphate receptors in the pathobiology of acute lung injury V Natarajan, SM Dudek, JR Jacobson, L Moreno-Vinasco, LS Huang, ... American journal of respiratory cell and molecular biology 49 (1), 6-17, 2013 | 160 | 2013 |
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension J Chen, H Tang, JR Sysol, L Moreno-Vinasco, KM Shioura, T Chen, ... American journal of respiratory and critical care medicine 190 (9), 1032-1043, 2014 | 142 | 2014 |
Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis LS Huang, E Berdyshev, B Mathew, P Fu, IA Gorshkova, D He, W Ma, ... The FASEB Journal 27 (4), 1749-1760, 2013 | 104 | 2013 |
Lysophosphatidic acid receptor–2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice LS Huang, P Fu, P Patel, A Harijith, T Sun, Y Zhao, JGN Garcia, J Chun, ... American journal of respiratory cell and molecular biology 49 (6), 912-922, 2013 | 100 | 2013 |
Sphingosine kinase 1/S1P signaling contributes to pulmonary fibrosis by activating Hippo/YAP pathway and mitochondrial reactive oxygen species in lung fibroblasts LS Huang, T Sudhadevi, P Fu, PK Punathil-Kannan, DL Ebenezer, ... International journal of molecular sciences 21 (6), 2064, 2020 | 98 | 2020 |
The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic–epigenetic reprogramming and resolves inflammatory injury B Zhou, L Magana, Z Hong, LS Huang, S Chakraborty, Y Tsukasaki, ... Nature immunology 21 (11), 1430-1443, 2020 | 90 | 2020 |
Sphingolipids in pulmonary fibrosis LS Huang, V Natarajan Advances in biological regulation 57, 55-63, 2015 | 81 | 2015 |
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy LS Huang, EV Berdyshev, JT Tran, L Xie, J Chen, DL Ebenezer, ... Thorax 70 (12), 1138-1148, 2015 | 80 | 2015 |
Lysophosphatidylcholine Containing Docosahexaenoic Acid at the sn-1 Position is Anti-inflammatory LS Huang, ND Hung, DE Sok, MR Kim Lipids 45, 225-236, 2010 | 65 | 2010 |
The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis LS Huang, B Mathew, H Li, Y Zhao, SF Ma, I Noth, SP Reddy, A Harijith, ... American journal of respiratory and critical care medicine 189 (11), 1402-1415, 2014 | 64 | 2014 |
Protective action of honokiol, administered orally, against oxidative stress in brain of mice challenged with NMDA HS Cui, LS Huang, DE Sok, J Shin, BM Kwon, UJ Youn, K Bae Phytomedicine 14 (10), 696-700, 2007 | 58 | 2007 |
Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins A Harijith, S Pendyala, NM Reddy, T Bai, PV Usatyuk, E Berdyshev, ... The American journal of pathology 183 (4), 1169-1182, 2013 | 56 | 2013 |
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis V Suryadevara, L Huang, SJ Kim, P Cheresh, M Shaaya, M Bandela, P Fu, ... American Journal of Physiology-Lung Cellular and Molecular Physiology, 2019 | 36 | 2019 |
Sphingolipids in ventilator induced lung injury: role of sphingosine-1-phosphate lyase V Suryadevara, P Fu, DL Ebenezer, E Berdyshev, IA Bronova, LS Huang, ... International Journal of Molecular Sciences 19 (1), 114, 2018 | 35 | 2018 |
Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation LS Huang, P Jiang, C Feghali-Bostwick, SP Reddy, JGN Garcia, ... Free Radical Biology and Medicine 112, 162-173, 2017 | 34 | 2017 |
Phosphatidic acid produced by RalA-activated PLD2 stimulates caveolae-mediated endocytosis and trafficking in endothelial cells Y Jiang, MS Sverdlov, PT Toth, LS Huang, G Du, Y Liu, V Natarajan, ... Journal of Biological Chemistry 291 (39), 20729-20738, 2016 | 34 | 2016 |
Linoleoyl lysophosphatidylcholine is an efficient substrate for soybean lipoxygenase-1 LS Huang, MR Kim, DE Sok Archives of biochemistry and biophysics 455 (2), 119-126, 2006 | 30 | 2006 |
Oxygenation of arachidonoyl lysophospholipids by lipoxygenases from soybean, porcine leukocyte, or rabbit reticulocyte LS Huang, JS Kang, MR Kim, DE Sok Journal of agricultural and food chemistry 56 (4), 1224-1232, 2008 | 29 | 2008 |