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Baohai Shao
Baohai Shao
Verified email at uw.edu
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Year
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species
S Pennathur, C Bergt, B Shao, J Byun, SY Kassim, P Singh, PS Green, ...
Journal of Biological Chemistry 279 (41), 42977-42983, 2004
3272004
Tyrosine 192 in apolipoprotein AI is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport
B Shao, C Bergt, X Fu, P Green, JC Voss, MN Oda, JF Oram, ...
Journal of Biological Chemistry 280 (7), 5983-5993, 2005
2952005
Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein AI
B Shao, MN Oda, C Bergt, X Fu, PS Green, N Brot, JF Oram, JW Heinecke
Journal of Biological Chemistry 281 (14), 9001-9004, 2006
2572006
Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein
B Shao, MN Oda, JF Oram, JW Heinecke
Chemical research in toxicology 23 (3), 447-454, 2010
2332010
Humans with atherosclerosis have impaired ABCA1 cholesterol efflux and enhanced high-density lipoprotein oxidation by myeloperoxidase
B Shao, C Tang, A Sinha, PS Mayer, GD Davenport, N Brot, MN Oda, ...
Circulation research 114 (11), 1733-1742, 2014
2212014
Methionine oxidation impairs reverse cholesterol transport by apolipoprotein AI
B Shao, G Cavigiolio, N Brot, MN Oda, JW Heinecke
Proceedings of the National Academy of Sciences 105 (34), 12224-12229, 2008
2142008
Myeloperoxidase targets apolipoprotein AI, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions
B Shao, S Pennathur, JW Heinecke
Journal of Biological Chemistry 287 (9), 6375-6386, 2012
2072012
Serum amyloid A impairs the antiinflammatory properties of HDL
CY Han, C Tang, ME Guevara, H Wei, T Wietecha, B Shao, ...
The Journal of clinical investigation 126 (1), 266-281, 2016
1982016
Modifying apolipoprotein AI by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway
B Shao, S Pennathur, I Pagani, MN Oda, JL Witztum, JF Oram, ...
Journal of Biological Chemistry 285 (24), 18473-18484, 2010
1632010
HDL, lipid peroxidation, and atherosclerosis1
B Shao, JW Heinecke
Journal of lipid research 50 (4), 599-601, 2009
1582009
Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: an oxidative mechanism for regulating proteolysis during inflammation
Y Wang, H Rosen, DK Madtes, B Shao, TR Martin, JW Heinecke, X Fu
Journal of Biological Chemistry 282 (44), 31826-31834, 2007
1522007
Myeloperoxidase: an inflammatory enzyme for generating dysfunctional high density lipoprotein
B Shao, MN Oda, JF Oram, JW Heinecke
Current opinion in cardiology 21 (4), 322-328, 2006
1512006
The interplay between size, morphology, stability, and functionality of high-density lipoprotein subclasses
G Cavigiolio, B Shao, EG Geier, G Ren, JW Heinecke, MN Oda
Biochemistry 47 (16), 4770-4779, 2008
1342008
Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein AI
B Shao, X Fu, TO McDonald, PS Green, K Uchida, KD O'Brien, JF Oram, ...
Journal of biological chemistry 280 (43), 36386-36396, 2005
1342005
Exchange of apolipoprotein AI between lipid-associated and lipid-free states: a potential target for oxidative generation of dysfunctional high density lipoproteins
G Cavigiolio, EG Geier, B Shao, JW Heinecke, MN Oda
Journal of Biological Chemistry 285 (24), 18847-18857, 2010
1162010
Oxidation of apolipoprotein AI by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export 1
B Shao, C Tang, JW Heinecke, JF Oram
Journal of lipid research 51 (7), 1849-1858, 2010
1102010
Site-specific oxidation of apolipoprotein AI impairs cholesterol export by ABCA1, a key cardioprotective function of HDL
B Shao
Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012
1082012
Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes
JE Kanter, B Shao, F Kramer, S Barnhart, M Shimizu-Albergine, T Vaisar, ...
The Journal of clinical investigation 129 (10), 4165-4179, 2019
1022019
Patients with coronary endothelial dysfunction have impaired cholesterol efflux capacity and reduced HDL particle concentration
JS Monette, PM Hutchins, GE Ronsein, J Wimberger, AD Irwin, C Tang, ...
Circulation research 119 (1), 83-90, 2016
722016
Acrolein modifies apolipoprotein A‐I in the human artery wall
B Shao, KD O'BRIEN, TO McDonald, X Fu, JF Oram, K Uchida, ...
Annals of the New York Academy of Sciences 1043 (1), 396-403, 2005
702005
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