| Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein M Okuda, K Li, MR Beard, LA Showalter, F Scholle, SM Lemon, ... Gastroenterology 122 (2), 366-375, 2002 | 1151 | 2002 |
| Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus H Lerat, M Honda, MR Beard, K Loesch, J Sun, Y Yang, M Okuda, ... Gastroenterology 122 (2), 352-365, 2002 | 590 | 2002 |
| A phylogenetically conserved stem-loop structure at the 5′ border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation M Honda, MR Beard, LH Ping, SM Lemon Journal of virology 73 (2), 1165-1174, 1999 | 385 | 1999 |
| Large deletions induced by Cas9 cleavage F Adikusuma, S Piltz, MA Corbett, M Turvey, SR McColl, KJ Helbig, ... Nature 560 (7717), E8-E9, 2018 | 371 | 2018 |
| Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees CB Bigger, B Guerra, KM Brasky, G Hubbard, MR Beard, BA Luxon, ... Journal of virology 78 (24), 13779-13792, 2004 | 320 | 2004 |
| Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector KJ Helbig, DTY Lau, L Semendric, HAJ Harley, MR Beard Hepatology 42 (3), 702-710, 2005 | 280 | 2005 |
| HIV-1 infection of human macrophages directly induces viperin which inhibits viral production N Nasr, S Maddocks, SG Turville, AN Harman, N Woolger, KJ Helbig, ... Blood, The Journal of the American Society of Hematology 120 (4), 778-788, 2012 | 267 | 2012 |
| The role of viperin in the innate antiviral response KJ Helbig, MR Beard Journal of molecular biology 426 (6), 1210-1219, 2014 | 249 | 2014 |
| Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection FJ Ryan, CM Hope, MG Masavuli, MA Lynn, ZA Mekonnen, AEL Yeow, ... BMC medicine 20, 1-23, 2022 | 244 | 2022 |
| The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A KJ Helbig, NS Eyre, E Yip, S Narayana, K Li, G Fiches, EM McCartney, ... Hepatology 54 (5), 1506-1517, 2011 | 238 | 2011 |
| Interferon-stimulated genes as enhancers of antiviral innate immune signaling KM Crosse, EA Monson, MR Beard, KJ Helbig Journal of innate immunity 10 (2), 85-93, 2018 | 200 | 2018 |
| Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin KJ Helbig, JM Carr, JK Calvert, S Wati, JN Clarke, NS Eyre, SK Narayana, ... PLoS neglected tropical diseases 7 (4), e2178, 2013 | 195 | 2013 |
| The interferon-induced transmembrane proteins, IFITM1, IFITM2, and IFITM3 inhibit hepatitis C virus entry SK Narayana, KJ Helbig, EM McCartney, NS Eyre, RA Bull, A Eltahla, ... Journal of Biological Chemistry 290 (43), 25946-25959, 2015 | 187 | 2015 |
| Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells K Otani, M Korenaga, MR Beard, K Li, T Qian, LA Showalter, AK Singh, ... Gastroenterology 128 (1), 96-107, 2005 | 157 | 2005 |
| An infectious molecular clone of a Japanese genotype 1b hepatitis C virus MR Beard, G Abell, M Honda, A Carroll, M Gartland, B Clarke, K Suzuki, ... Hepatology 30 (1), 316-324, 1999 | 154 | 1999 |
| Expression of the CXCR3 ligand I‐TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation KJ Helbig, A Ruszkiewicz, L Semendric, HAJ Harley, SR McColl, ... Hepatology 39 (5), 1220-1229, 2004 | 144 | 2004 |
| CD4+ T-Cell Deficiency in HIV Patients Responding to Antiretroviral Therapy Is Associated With Increased Expression of Interferon-Stimulated Genes in CD4+ T … S Fernandez, S Tanaskovic, K Helbig, R Rajasuriar, M Kramski, ... The Journal of infectious diseases 204 (12), 1927-1935, 2011 | 128 | 2011 |
| Viperin is an important host restriction factor in control of Zika virus infection KH Van der Hoek, NS Eyre, B Shue, O Khantisitthiporn, K Glab-Ampi, ... Scientific reports 7 (1), 4475, 2017 | 121 | 2017 |
| Cellular response to conditional expression of hepatitis C virus core protein in Huh7 cultured human hepatoma cells K Li, T Prow, SM Lemon, MR Beard Hepatology 35 (5), 1237-1246, 2002 | 117 | 2002 |
| Dengue virus infection induces upregulation of GRP78, which acts to chaperone viral antigen production S Wati, ML Soo, P Zilm, P Li, AW Paton, CJ Burrell, M Beard, JM Carr Journal of virology 83 (24), 12871-12880, 2009 | 115 | 2009 |