| Mitochondria, calcium and pro-apoptotic proteins as mediators in cell death signaling SS Smaili, YT Hsu, ACP Carvalho, TR Rosenstock, JC Sharpe, RJ Youle Brazilian Journal of medical and biological research 36, 183-190, 2003 | 201 | 2003 |
| Dysregulation of autophagy as a common mechanism in lysosomal storage diseases E Seranova, KJ Connolly, M Zatyka, TR Rosenstock, T Barrett, ... Essays in biochemistry 61 (6), 733-749, 2017 | 178 | 2017 |
| New avenues for the treatment of Huntington’s disease A Kim, K Lalonde, A Truesdell, P Gomes Welter, PS Brocardo, ... International journal of molecular sciences 22 (16), 8363, 2021 | 161 | 2021 |
| Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in … M Ribeiro, TR Rosenstock, AM Oliveira, CR Oliveira, AC Rego Free Radical Biology and Medicine 74, 129-144, 2014 | 153 | 2014 |
| Mitochondrial calcium, oxidative stress and apoptosis in a neurodegenerative disease model induced by 3‐nitropropionic acid TR Rosenstock, ACP Carvalho, A Jurkiewicz, R Frussa‐Filho, SS Smaili Journal of neurochemistry 88 (5), 1220-1228, 2004 | 146 | 2004 |
| Comparative mitochondrial-based protective effects of resveratrol and nicotinamide in Huntington’s disease models L Naia, TR Rosenstock, AM Oliveira, SI Oliveira-Sousa, GL Caldeira, ... Molecular neurobiology 54 (7), 5385-5399, 2017 | 136 | 2017 |
| Gene expression control by glucocorticoid receptors during innate immune responses AM Xavier, AKO Anunciato, TR Rosenstock, I Glezer Frontiers in endocrinology 7, 31, 2016 | 118 | 2016 |
| Calcium and cell death signaling in neurodegeneration and aging S Smaili, H Hirata, R Ureshino, PT Monteforte, AP Morales, ML Muler, ... Anais da Academia Brasileira de Ciencias 81, 467-475, 2009 | 90 | 2009 |
| Activation of IGF‐1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's disease human lymphoblasts AC Naia, L., Ferreira, I.L., Cunha-Oliveira, T Mol Neurobiol, 2014 | 81* | 2014 |
| Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - from clinical features to the bench. TR Rosenstock, AI Duarte, AC Rego Curr Drug Targets 11 (10), 1218-1236, 2010 | 79 | 2010 |
| Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells M Ribeiro, TR Rosenstock, T Cunha-Oliveira, IL Ferreira, CR Oliveira, ... Free Radical Biology and Medicine 53 (10), 1857-1867, 2012 | 73 | 2012 |
| Histone deacetylase inhibitors protect against pyruvate dehydrogenase dysfunction in Huntington's disease L Naia, T Cunha-Oliveira, J Rodrigues, TR Rosenstock, A Oliveira, ... Journal of Neuroscience 37 (10), 2776-2794, 2017 | 65 | 2017 |
| Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics L Naia, C Carmo, S Campesan, L Fão, VE Cotton, J Valero, C Lopes, ... Free Radical Biology and Medicine 163, 163-179, 2021 | 59 | 2021 |
| Mitochondrial dysfunction, neurogenesis, and epigenetics: putative implications for amyotrophic lateral sclerosis neurodegeneration and treatment ML Calió, E Henriques, A Siena, CRA Bertoncini, J Gil-Mohapel, ... Frontiers in Neuroscience 14, 679, 2020 | 56 | 2020 |
| Bax affects intracellular Ca2+ stores and induces Ca2+ wave propagation ACP Carvalho, J Sharpe, TR Rosenstock, AFV Teles, AJ Kowaltowski, ... Cell Death & Differentiation 11 (12), 1265-1276, 2004 | 54 | 2004 |
| Increase in bax expression and apoptosis are associated in Huntington's disease progression A Teles, TR Rosenstock, CS Okuno, GS Lopes, CRA Bertoncini, ... Neuroscience Letters 438 (1), 59-63, 2008 | 49 | 2008 |
| Chemical screening approaches enabling drug discovery of autophagy modulators for biomedical applications in human diseases PK Panda, A Fahrner, S Vats, E Seranova, V Sharma, M Chipara, P Desai, ... Frontiers in cell and developmental biology 7, 38, 2019 | 48 | 2019 |
| Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin L Naia, M Ribeiro, J Rodrigues, AI Duarte, C Lopes, TR Rosenstock, ... Neuropeptides 58, 73-81, 2016 | 38 | 2016 |
| CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium AM Xavier, RG Ludwig, MH Nagai, TJ de Almeida, HM Watanabe, ... Scientific reports 6 (1), 25507, 2016 | 38 | 2016 |
| FK506 ameliorates cell death features in Huntington’s disease striatal cell models TR Rosenstock, OM de Brito, V Lombardi, S Louros, M Ribeiro, S Almeida, ... Neurochemistry international 59 (5), 600-609, 2011 | 36 | 2011 |
Ana Cristina Rego (PhD)Center for Neuroscience and Cell Biology, and Faculty of Medicine, University of CoimbraVerified email at cnc.cj.uc.pt