| The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells D Dixit, BC Prager, RC Gimple, HX Poh, Y Wang, Q Wu, Z Qiu, RL Kidwell, ... Cancer discovery 11 (2), 480-499, 2021 | 312 | 2021 |
| Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin L Min, Y Ji, L Bakiri, Z Qiu, J Cen, X Chen, L Chen, H Scheuch, H Zheng, ... Nature cell biology 14 (11), 1203-1211, 2012 | 287 | 2012 |
| Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions M Tang, Q Xie, RC Gimple, Z Zhong, T Tam, J Tian, RL Kidwell, Q Wu, ... Cell research 30 (10), 833-853, 2020 | 244 | 2020 |
| Targeting glioblastoma stem cells through disruption of the circadian clock Z Dong, G Zhang, M Qu, RC Gimple, Q Wu, Z Qiu, BC Prager, X Wang, ... Cancer discovery 9 (11), 1556-1573, 2019 | 241 | 2019 |
| A pharmacogenomic landscape in human liver cancers Z Qiu, H Li, Z Zhang, Z Zhu, S He, X Wang, P Wang, J Qin, L Zhuang, ... Cancer Cell 36 (2), 179-193. e11, 2019 | 181 | 2019 |
| Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities A Choudhury, ST Magill, CD Eaton, BC Prager, WC Chen, MA Cady, ... Nature genetics 54 (5), 649-659, 2022 | 179 | 2022 |
| Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ... Science translational medicine 11 (504), eaau4972, 2019 | 147 | 2019 |
| Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes L Sun, Y Wang, J Cen, X Ma, L Cui, Z Qiu, Z Zhang, H Li, RZ Yang, ... Nature cell biology 21 (8), 1015-1026, 2019 | 144 | 2019 |
| CRISPR screening of CAR T cells and cancer stem cells reveals critical dependencies for cell-based therapies D Wang, BC Prager, RC Gimple, B Aguilar, D Alizadeh, H Tang, D Lv, ... Cancer discovery 11 (5), 1192-1211, 2021 | 127 | 2021 |
| Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ... Journal of Experimental Medicine 216 (5), 1071-1090, 2019 | 125 | 2019 |
| miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression W Mu, C Hu, H Zhang, Z Qu, J Cen, Z Qiu, C Li, H Ren, Y Li, X He, X Shi, ... Cell research 25 (4), 477-495, 2015 | 100 | 2015 |
| FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells JZ Shen, Z Qiu, Q Wu, D Finlay, G Garcia, D Sun, J Rantala, W Barshop, ... Cell 184 (2), 352-369. e23, 2021 | 80 | 2021 |
| Hepatocellular carcinoma cell lines retain the genomic and transcriptomic landscapes of primary human cancers Z Qiu, K Zou, L Zhuang, J Qin, H Li, C Li, Z Zhang, X Chen, J Cen, Z Meng, ... Scientific reports 6 (1), 27411, 2016 | 72 | 2016 |
| β2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages D Li, Q Zhang, L Li, K Chen, J Yang, D Dixit, RC Gimple, S Ci, C Lu, L Hu, ... Cancer research 82 (18), 3321-3334, 2022 | 65 | 2022 |
| Arid1a regulates response to anti-angiogenic therapy in advanced hepatocellular carcinoma C Hu, W Li, F Tian, K Jiang, X Liu, J Cen, Q He, Z Qiu, Y Kienast, Z Wang, ... Journal of hepatology 68 (3), 465-475, 2018 | 65 | 2018 |
| Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells Z Qiu, L Zhao, JZ Shen, Z Liang, Q Wu, K Yang, L Min, RC Gimple, ... Cancer Discovery 12 (2), 502-521, 2022 | 53 | 2022 |
| PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine D Lv, RC Gimple, C Zhong, Q Wu, K Yang, BC Prager, B Godugu, Z Qiu, ... Developmental cell 57 (12), 1466-1481. e6, 2022 | 50 | 2022 |
| Note of caution: Contaminations of hepatocellular cell lines S Rebouissou, J Zucman-Rossi, R Moreau, Z Qiu, L Hui Journal of hepatology 67 (5), 896-897, 2017 | 50 | 2017 |
| ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance L Jiang, Y Hao, C Shao, Q Wu, BC Prager, RC Gimple, G Sulli, LJY Kim, ... The Journal of Clinical Investigation 132 (6), 2022 | 47 | 2022 |
| Targeting microglial metabolic rewiring synergizes with immune-checkpoint blockade therapy for glioblastoma Z Ye, X Ai, K Yang, Z Yang, F Fei, X Liao, Z Qiu, RC Gimple, H Yuan, ... Cancer discovery 13 (4), 974-1001, 2023 | 44 | 2023 |