Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia Y Peng, C Cui, Y He, Ouzhuluobu, H Zhang, D Yang, Q Zhang, ... Molecular biology and evolution 34 (4), 818-830, 2017 | 161 | 2017 |
Long-read assembly of the Chinese rhesus macaque genome and identification of ape-specific structural variants Y He, X Luo, B Zhou, T Hu, X Meng, PA Audano, ZN Kronenberg, ... Nature communications 10 (1), 4233, 2019 | 81 | 2019 |
The transcriptomic landscape of yaks reveals molecular pathways for high altitude adaptation X Qi, Q Zhang, Y He, L Yang, X Zhang, P Shi, L Yang, Z Liu, F Zhang, ... Genome biology and evolution 11 (1), 72-85, 2019 | 74 | 2019 |
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation J Xin, H Zhang, Y He, Z Duren, C Bai, L Chen, X Luo, DS Yan, C Zhang, ... Nature communications 11 (1), 4928, 2020 | 68 | 2020 |
HMOX2 Functions as a Modifier Gene for High‐Altitude Adaptation in Tibetans D Yang, Y Peng, null Ouzhuluobu, null Bianbazhuoma, C Cui, null Bianba, ... Human mutation 37 (2), 216-223, 2016 | 48 | 2016 |
Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders L Deng, C Zhang, K Yuan, Y Gao, Y Pan, X Ge, Y He, Y Yuan, Y Lu, ... National Science Review 6 (6), 1201-1222, 2019 | 46 | 2019 |
De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation Ouzhuluobu, Y He, H Lou, C Cui, L Deng, Y Gao, W Zheng, Y Guo, ... National Science Review 7 (2), 391-402, 2020 | 43 | 2020 |
Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys X Luo, Y He, C Zhang, X He, L Yan, M Li, T Hu, Y Hu, J Jiang, X Meng, ... Nature Communications 10 (1), 5525, 2019 | 33 | 2019 |
Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia Y He, X Qi, Ouzhuluobu, S Liu, J Li, H Zhang, Baimakangzhuo, C Bai, ... National Science Review 5 (4), 516-529, 2018 | 33 | 2018 |
Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans W Zheng, Y He, Y Guo, T Yue, H Zhang, J Li, B Zhou, X Zeng, L Li, ... Genome biology 24 (1), 73, 2023 | 29 | 2023 |
Genetic adaptation of skin pigmentation in highland Tibetans Z Yang, C Bai, Y Pu, Q Kong, Y Guo, Ouzhuluobu, Gengdeng, X Liu, ... Proceedings of the National Academy of Sciences 119 (40), e2200421119, 2022 | 24 | 2022 |
GCH1 plays a role in the high-altitude adaptation of Tibetans YB Guo, YX He, CY Cui, P Yi, C Bai, YY Pan, W Guo, H Zhang, XM Zhang, ... Zoological Research 38 (3), 155, 2017 | 24 | 2017 |
EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production WS Zheng, YX He, CY Cui, Y Peng, CJ Bai, YY Pan, W Guo, H Zhang, ... Zoological research 38 (3), 163, 2017 | 19 | 2017 |
Cross‐altitude analysis suggests a turning point at the elevation of 4,500 m for polycythemia prevalence in Tibetans H Zhang, Y He, C Cui, Ouzhuluobu, Baimakangzhuo, Duojizhuoma, ... American journal of hematology 92 (9), E552-E554, 2017 | 15 | 2017 |
Polygenic adaptation leads to a higher reproductive fitness of native Tibetans at high altitude Y He, Y Guo, W Zheng, T Yue, H Zhang, B Wang, Z Feng, C Cui, K Liu, ... Current Biology 33 (19), 4037-4051. e5, 2023 | 12 | 2023 |
A late Pleistocene human genome from southwest China X Zhang, X Ji, C Li, T Yang, J Huang, Y Zhao, Y Wu, S Ma, Y Pang, ... Current Biology 32 (14), 3095-3109. e5, 2022 | 12 | 2022 |
Genetic and cultural adaptations underlie the establishment of dairy pastoralism in the Tibetan Plateau MS Peng, YH Liu, QK Shen, XH Zhang, J Dong, JX Li, H Zhao, H Zhang, ... BMC biology 21 (1), 208, 2023 | 8 | 2023 |
Exploring the primate genome: Unraveling the mysteries of evolution and human disease Y He, Y Mao The Innovation 4 (4), 2023 | 7 | 2023 |
Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development T Yue, Y Guo, X Qi, W Zheng, H Zhang, B Wang, K Liu, B Zhou, X Zeng, ... Elife 12, RP89004, 2024 | 5 | 2024 |
Comparative genomics of macaques and integrated insights into genetic variation and population history S Zhang, N Xu, L Fu, X Yang, Y Li, Z Yang, Y Feng, K Ma, X Jiang, J Han, ... BioRxiv, 2024.04. 07.588379, 2024 | 5 | 2024 |