| Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease A Ghosh, A Roy, X Liu, JH Kordower, EJ Mufson, DM Hartley, S Ghosh, ... Proceedings of the National Academy of Sciences 104 (47), 18754-18759, 2007 | 528 | 2007 |
| Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease HB Dodiya, CB Forsyth, RM Voigt, PA Engen, J Patel, M Shaikh, SJ Green, ... Neurobiology of disease 135, 104352, 2020 | 267 | 2020 |
| Up-regulation of microglial CD11b expression by nitric oxide A Roy, YK Fung, X Liu, K Pahan Journal of Biological Chemistry 281 (21), 14971-14980, 2006 | 239 | 2006 |
| Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease A Ghosh, A Roy, J Matras, S Brahmachari, HE Gendelman, K Pahan Journal of Neuroscience 29 (43), 13543-13556, 2009 | 202 | 2009 |
| Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α A Roy, M Jana, GT Corbett, S Ramaswamy, JH Kordower, FJ Gonzalez, ... Cell reports 4 (4), 724-737, 2013 | 185 | 2013 |
| HMG-CoA reductase inhibitors bind to PPARα to upregulate neurotrophin expression in the brain and improve memory in mice A Roy, M Jana, M Kundu, GT Corbett, SB Rangaswamy, RK Mishra, ... Cell metabolism 22 (2), 253-265, 2015 | 177 | 2015 |
| Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases A Roy, A Jana, K Yatish, MB Freidt, YK Fung, JA Martinson, K Pahan Free Radical Biology and Medicine 45 (5), 686-699, 2008 | 160 | 2008 |
| Cinnamic acid activates PPARα to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model S Chandra, A Roy, M Jana, K Pahan Neurobiology of disease 124, 379-395, 2019 | 152 | 2019 |
| Up-Regulation of Neurotrophic Factors by Cinnamon and its Metabolite Sodium Benzoate: Therapeutic Implications for Neurodegenerative Disorders A Jana, KK Modi, A Roy, JA Anderson, RB van Breemen, K Pahan Journal of Neuroimmune Pharmacology, 1-17, 2013 | 151 | 2013 |
| Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease A Roy, A Ghosh, A Jana, X Liu, S Brahmachari, HE Gendelman, K Pahan PLoS ONE 7 (6), e38113, 2012 | 146 | 2012 |
| Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo D Dutta, M Jana, M Majumder, S Mondal, A Roy, K Pahan Nature communications 12 (1), 5382, 2021 | 133 | 2021 |
| Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology SB Rangasamy, M Jana, A Roy, GT Corbett, M Kundu, S Chandra, ... The Journal of Clinical Investigation 128 (10), 4297-4312, 2018 | 130 | 2018 |
| Suppression of nuclear factor-kappa B activation and inflammation in microglia by a physically-modified saline S Khasnavis, A Jana, A Roy, T Wood, S Ghosh, R Watson, K Pahan Journal of Biological Chemistry, 2012 | 127 | 2012 |
| Cinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer’s Disease KK Modi, A Roy, S Brahmachari, SB Rangasamy, K Pahan PloS one 10 (6), e0130398, 2015 | 118 | 2015 |
| Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-α S Dasgupta, A Roy, M Jana, DM Hartley, K Pahan Molecular pharmacology 72 (4), 934-946, 2007 | 116 | 2007 |
| Prospects of statins in Parkinson disease A Roy, K Pahan The Neuroscientist 17 (3), 244-255, 2011 | 112 | 2011 |
| Gemfibrozil, stretching arms beyond lipid lowering A Roy, K Pahan Immunopharmacology and immunotoxicology 31 (3), 339-351, 2009 | 100 | 2009 |
| Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory D Patel, A Roy, M Kundu, M Jana, CH Luan, FJ Gonzalez, K Pahan Proceedings of the National Academy of Sciences 115 (31), E7408-E7417, 2018 | 87 | 2018 |
| Identification and characterization of PPARα ligands in the hippocampus A Roy, M Kundu, M Jana, RK Mishra, Y Yung, CH Luan, FJ Gonzalez, ... Nature chemical biology 12 (12), 1075-1083, 2016 | 85 | 2016 |
| Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase S Khasnavis, A Ghosh, A Roy, K Pahan Journal of Biological Chemistry 288 (29), 20843-20855, 2013 | 71 | 2013 |