Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression RK Thakur, P Kumar, K Halder, A Verma, A Kar, JL Parent, R Basundra, ... Nucleic acids research 37 (1), 172-183, 2009 | 203 | 2009 |
Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex–dependent fashion D Saha, A Singh, T Hussain, V Srivastava, S Sengupta, A Kar, P Dhapola, ... Journal of Biological Chemistry 292 (37), 15205-15215, 2017 | 68 | 2017 |
Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex T Hussain, D Saha, G Purohit, A Kar, A Kishore Mukherjee, S Sharma, ... Scientific reports 7 (1), 11541, 2017 | 63 | 2017 |
Non-metastatic 2 (NME2)-mediated suppression of lung cancer metastasis involves transcriptional regulation of key cell adhesion factor vinculin RK Thakur, VK Yadav, A Kumar, A Singh, K Pal, L Hoeppner, D Saha, ... Nucleic acids research 42 (18), 11589-11600, 2014 | 52 | 2014 |
Molecular basis of recognition of quadruplexes human telomere and c-myc promoter by the putative anticancer agent sanguinarine S Ghosh, SK Pradhan, A Kar, S Chowdhury, D Dasgupta Biochimica Et Biophysica Acta (BBA)-General Subjects 1830 (8), 4189-4201, 2013 | 48 | 2013 |
Telomere repeat–binding factor 2 binds extensively to extra-telomeric G-quadruplexes and regulates the epigenetic status of several gene promoters AK Mukherjee, S Sharma, S Bagri, R Kutum, P Kumar, A Hussain, P Singh, ... Journal of biological chemistry 294 (47), 17709-17722, 2019 | 46 | 2019 |
A new view of the t-loop junction: implications for self-primed telomere extension, expansion of disease-related nucleotide repeat blocks, and telomere evolution L Tomaska, J Nosek, A Kar, S Willcox, JD Griffith Frontiers in genetics 10, 792, 2019 | 38 | 2019 |
Metastases suppressor NME2 associates with telomere ends and telomerase and reduces telomerase activity within cells A Kar, D Saha, G Purohit, A Singh, P Kumar, VK Yadav, P Kumar, ... Nucleic acids research 40 (6), 2554-2565, 2012 | 36 | 2012 |
Long repeating (TTAGGG) n single-stranded DNA self-condenses into compact beaded filaments stabilized by G-quadruplex formation A Kar, N Jones, NÖ Arat, R Fishel, JD Griffith Journal of Biological Chemistry 293 (24), 9473-9485, 2018 | 32 | 2018 |
Transcription of telomeric DNA leads to high levels of homologous recombination and t-loops A Kar, S Willcox, JD Griffith Nucleic acids research 44 (19), 9369-9380, 2016 | 32 | 2016 |
Ellipticine binds to a human telomere sequence: an additional mode of action as a putative anticancer agent? S Ghosh, A Kar, S Chowdhury, D Dasgupta Biochemistry 52 (24), 4127-4137, 2013 | 30 | 2013 |
Inhibition of telomerase activity by NME2: impact on metastasis suppression? A Kar, S Chowdhury Naunyn-Schmiedeberg's archives of pharmacology 388, 235-241, 2015 | 9 | 2015 |
Functional genomics of lung cancer progression reveals mechanism of metastasis suppressor function RK Thakur, VK Yadav, A Kumar, R Basundra, A Kar, R Halder, A Singh, ... Molecular Cytogenetics 7 (Suppl 1), I9, 2014 | 2 | 2014 |
Human NTHL1 expression and subcellular distribution determines cisplatin sensitivity in human lung epithelial and non-small cell lung cancer cells A Kar, NP Degtyareva, PW Doetsch NAR cancer 6 (1), zcae006, 2024 | 1 | 2024 |
Redox stress responses and human disease: NTHL1 at the intersection of DNA damage repair and cancer A Kar, NP Degtyareva, PW Doetsch | 1 | 2020 |
Dysregulation of NTHL1 and Sensitivity to Chemotherapeutic Agents in Human Cells. A Kar, NP Degtyareva, PW Doetsch ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 61, 88-89, 2020 | | 2020 |
Dysregulation of Human NTHL1 and Genomic Instability. A Kar, PW Doetsch ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 60, 67-67, 2019 | | 2019 |
Transcriptional activity of TRF2 is telomere length dependent AK Mukherjee, S Sharma, P Dhapola, D Saha, T Hussain, SD Roy, ... bioRxiv, 056481, 2016 | | 2016 |