Exercise training reduces resting heart rate via downregulation of the funny channel HCN4 A D’Souza, A Bucchi, AB Johnsen, SJRJ Logantha, O Monfredi, J Yanni, ... Nature communications 5 (1), 3775, 2014 | 319 | 2014 |
Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues H Dobrzynski, RH Anderson, A Atkinson, Z Borbas, A D'Souza, JF Fraser, ... Pharmacology & therapeutics 139 (2), 260-288, 2013 | 229 | 2013 |
Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms N Black, A D’Souza, Y Wang, H Piggins, H Dobrzynski, G Morris, ... Heart rhythm 16 (2), 298-307, 2019 | 190 | 2019 |
Is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone? MR Boyett, A D'souza, H Zhang, GM Morris, H Dobrzynski, O Monfredi Journal of Applied Physiology 114 (9), 1351-1355, 2013 | 118 | 2013 |
Pathogenesis and pathophysiology of accelerated atherosclerosis in the diabetic heart A D’Souza, M Hussain, FC Howarth, NM Woods, K Bidasee, J Singh Molecular and cellular biochemistry 331, 89-116, 2009 | 108 | 2009 |
Targeting miR-423-5p reverses exercise training–induced HCN4 channel remodeling and sinus bradycardia A D’Souza, CM Pearman, Y Wang, S Nakao, SJRJ Logantha, C Cox, ... Circulation research 121 (9), 1058-1068, 2017 | 101 | 2017 |
CrossTalk opposing view: bradycardia in the trained athlete is attributable to a downregulation of a pacemaker channel in the sinus node A D'Souza, S Sharma, MR Boyett The Journal of physiology 593 (Pt 8), 1749, 2015 | 90 | 2015 |
Left ventricle structural remodelling in the prediabetic Goto–Kakizaki rat A D'Souza, FC Howarth, J Yanni, H Dobryznski, MR Boyett, E Adeghate, ... Experimental physiology 96 (9), 875-888, 2011 | 80 | 2011 |
A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate A D’souza, Y Wang, C Anderson, A Bucchi, M Baruscotti, S Olieslagers, ... Heart rhythm 18 (5), 801-810, 2021 | 71 | 2021 |
CrossTalk opposing view: heart rate variability as a measure of cardiac autonomic responsiveness is fundamentally flawed M Boyett, Y Wang, A D'Souza The Journal of physiology 597 (10), 2599, 2019 | 58 | 2019 |
Carbonylation induces heterogeneity in cardiac ryanodine receptor function in diabetes mellitus CH Shao, C Tian, S Ouyang, CJ Moore, F Alomar, I Nemet, A D’Souza, ... Molecular pharmacology 82 (3), 383-399, 2012 | 55 | 2012 |
Silencing miR-370-3p rescues funny current and sinus node function in heart failure J Yanni, A D’Souza, Y Wang, N Li, BJ Hansen, SO Zakharkin, M Smith, ... Scientific reports 10 (1), 11279, 2020 | 45 | 2020 |
Point: Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function MR Boyett, Y Wang, S Nakao, J Ariyaratnam, G Hart, O Monfredi, ... Journal of applied physiology 123 (3), 684-685, 2017 | 45 | 2017 |
Chronic effects of mild hyperglycaemia on left ventricle transcriptional profile and structural remodelling in the spontaneously type 2 diabetic Goto-Kakizaki rat A D’Souza, FC Howarth, J Yanni, H Dobrzynski, MR Boyett, E Adeghate, ... Heart Failure Reviews 19, 65-74, 2014 | 42 | 2014 |
Intrinsic electrical remodeling underlies atrioventricular block in athletes P Mesirca, S Nakao, SD Nissen, G Forte, C Anderson, T Trussell, J Li, ... Circulation research 129 (1), e1-e20, 2021 | 34 | 2021 |
Identification of Key Small Non‐Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node M Petkova, AJ Atkinson, J Yanni, L Stuart, AJ Aminu, AD Ivanova, ... Journal of the American Heart Association 9 (20), e016590, 2020 | 32 | 2020 |
TBX18 overexpression enhances pacemaker function in a rat subsidiary atrial pacemaker model of sick sinus syndrome M Choudhury, N Black, A Alghamdi, A D'Souza, R Wang, J Yanni, ... The Journal of Physiology 596 (24), 6141-6155, 2018 | 29 | 2018 |
Characterization of a right atrial subsidiary pacemaker and acceleration of the pacing rate by HCN over-expression GM Morris, A D'Souza, H Dobrzynski, M Lei, M Choudhury, R Billeter, ... Cardiovascular research 100 (1), 160-169, 2013 | 28 | 2013 |
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease MR Boyett, J Yanni, J Tellez, A Bucchi, P Mesirca, X Cai, SJRJ Logantha, ... Progress in biophysics and molecular biology 166, 61-85, 2021 | 24 | 2021 |
RNAseq shows an all-pervasive day-night rhythm in the transcriptome of the pacemaker of the heart Y Wang, C Anderson, H Dobrzynski, G Hart, A D’Souza, MR Boyett Scientific Reports 11 (1), 3565, 2021 | 23 | 2021 |