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Alicia D'souza
Alicia D'souza
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Exercise training reduces resting heart rate via downregulation of the funny channel HCN4
A D’Souza, A Bucchi, AB Johnsen, SJRJ Logantha, O Monfredi, J Yanni, ...
Nature communications 5 (1), 3775, 2014
3192014
Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues
H Dobrzynski, RH Anderson, A Atkinson, Z Borbas, A D'Souza, JF Fraser, ...
Pharmacology & therapeutics 139 (2), 260-288, 2013
2292013
Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms
N Black, A D’Souza, Y Wang, H Piggins, H Dobrzynski, G Morris, ...
Heart rhythm 16 (2), 298-307, 2019
1902019
Is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone?
MR Boyett, A D'souza, H Zhang, GM Morris, H Dobrzynski, O Monfredi
Journal of Applied Physiology 114 (9), 1351-1355, 2013
1182013
Pathogenesis and pathophysiology of accelerated atherosclerosis in the diabetic heart
A D’Souza, M Hussain, FC Howarth, NM Woods, K Bidasee, J Singh
Molecular and cellular biochemistry 331, 89-116, 2009
1082009
Targeting miR-423-5p reverses exercise training–induced HCN4 channel remodeling and sinus bradycardia
A D’Souza, CM Pearman, Y Wang, S Nakao, SJRJ Logantha, C Cox, ...
Circulation research 121 (9), 1058-1068, 2017
1012017
CrossTalk opposing view: bradycardia in the trained athlete is attributable to a downregulation of a pacemaker channel in the sinus node
A D'Souza, S Sharma, MR Boyett
The Journal of physiology 593 (Pt 8), 1749, 2015
902015
Left ventricle structural remodelling in the prediabetic Goto–Kakizaki rat
A D'Souza, FC Howarth, J Yanni, H Dobryznski, MR Boyett, E Adeghate, ...
Experimental physiology 96 (9), 875-888, 2011
802011
A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate
A D’souza, Y Wang, C Anderson, A Bucchi, M Baruscotti, S Olieslagers, ...
Heart rhythm 18 (5), 801-810, 2021
712021
CrossTalk opposing view: heart rate variability as a measure of cardiac autonomic responsiveness is fundamentally flawed
M Boyett, Y Wang, A D'Souza
The Journal of physiology 597 (10), 2599, 2019
582019
Carbonylation induces heterogeneity in cardiac ryanodine receptor function in diabetes mellitus
CH Shao, C Tian, S Ouyang, CJ Moore, F Alomar, I Nemet, A D’Souza, ...
Molecular pharmacology 82 (3), 383-399, 2012
552012
Silencing miR-370-3p rescues funny current and sinus node function in heart failure
J Yanni, A D’Souza, Y Wang, N Li, BJ Hansen, SO Zakharkin, M Smith, ...
Scientific reports 10 (1), 11279, 2020
452020
Point: Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function
MR Boyett, Y Wang, S Nakao, J Ariyaratnam, G Hart, O Monfredi, ...
Journal of applied physiology 123 (3), 684-685, 2017
452017
Chronic effects of mild hyperglycaemia on left ventricle transcriptional profile and structural remodelling in the spontaneously type 2 diabetic Goto-Kakizaki rat
A D’Souza, FC Howarth, J Yanni, H Dobrzynski, MR Boyett, E Adeghate, ...
Heart Failure Reviews 19, 65-74, 2014
422014
Intrinsic electrical remodeling underlies atrioventricular block in athletes
P Mesirca, S Nakao, SD Nissen, G Forte, C Anderson, T Trussell, J Li, ...
Circulation research 129 (1), e1-e20, 2021
342021
Identification of Key Small Non‐Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node
M Petkova, AJ Atkinson, J Yanni, L Stuart, AJ Aminu, AD Ivanova, ...
Journal of the American Heart Association 9 (20), e016590, 2020
322020
TBX18 overexpression enhances pacemaker function in a rat subsidiary atrial pacemaker model of sick sinus syndrome
M Choudhury, N Black, A Alghamdi, A D'Souza, R Wang, J Yanni, ...
The Journal of Physiology 596 (24), 6141-6155, 2018
292018
Characterization of a right atrial subsidiary pacemaker and acceleration of the pacing rate by HCN over-expression
GM Morris, A D'Souza, H Dobrzynski, M Lei, M Choudhury, R Billeter, ...
Cardiovascular research 100 (1), 160-169, 2013
282013
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease
MR Boyett, J Yanni, J Tellez, A Bucchi, P Mesirca, X Cai, SJRJ Logantha, ...
Progress in biophysics and molecular biology 166, 61-85, 2021
242021
RNAseq shows an all-pervasive day-night rhythm in the transcriptome of the pacemaker of the heart
Y Wang, C Anderson, H Dobrzynski, G Hart, A D’Souza, MR Boyett
Scientific Reports 11 (1), 3565, 2021
232021
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