The changing paradigm of intron retention: regulation, ramifications and recipes G Monteuuis, JJL Wong, CG Bailey, U Schmitz, JEJ Rasko Nucleic acids research 47 (22), 11497-11513, 2019 | 173 | 2019 |
Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer X Lai, M Eberhardt, U Schmitz, J Vera Nucleic acids research 47 (15), 7753-7766, 2019 | 168 | 2019 |
E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry V Alla, BS Kowtharapu, D Engelmann, S Emmrich, U Schmitz, M Steder, ... Cell cycle 11 (16), 3067-3078, 2012 | 117 | 2012 |
Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma A Bhattacharya, U Schmitz, O Wolkenhauer, M Schönherr, Y Raatz, ... Oncogene 32 (26), 3175-3183, 2013 | 108 | 2013 |
A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages CR Edwards, W Ritchie, JJL Wong, U Schmitz, R Middleton, X An, ... Blood, The Journal of the American Society of Hematology 127 (17), e24-e34, 2016 | 107 | 2016 |
E2F1 induces miR‐224/452 expression to drive EMT through TXNIP downregulation S Knoll, K Fürst, B Kowtharapu, U Schmitz, S Marquardt, O Wolkenhauer, ... EMBO reports 15 (12), 1315-1329, 2014 | 106 | 2014 |
Intron retention enhances gene regulatory complexity in vertebrates U Schmitz, N Pinello, F Jia, S Alasmari, W Ritchie, MC Keightley, S Shini, ... Genome biology 18, 1-15, 2017 | 104 | 2017 |
Cooperative gene regulation by microRNA pairs and their identification using a computational workflow U Schmitz, X Lai, F Winter, O Wolkenhauer, J Vera, SK Gupta Nucleic acids research 42 (12), 7539-7552, 2014 | 102 | 2014 |
Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs X Lai, U Schmitz, SK Gupta, A Bhattacharya, M Kunz, O Wolkenhauer, ... Nucleic Acids Research, 2012 | 102 | 2012 |
MicroRNA–mRNA interactions in colorectal cancer and their role in tumor progression R Amirkhah, U Schmitz, M Linnebacher, O Wolkenhauer, A Farazmand Genes, Chromosomes and Cancer 54 (3), 129-141, 2015 | 94 | 2015 |
miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy A Bhattacharya, U Schmitz, Y Raatz, M Schönherr, T Kottek, M Schauer, ... Oncotarget 6 (5), 2966, 2014 | 91 | 2014 |
Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures FM Khan, S Marquardt, SK Gupta, S Knoll, U Schmitz, A Spitschak, ... Nature communications 8 (1), 198, 2017 | 89 | 2017 |
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance X Lai, SK Gupta, U Schmitz, S Marquardt, S Knoll, A Spitschak, ... Theranostics 8 (4), 1106, 2018 | 73 | 2018 |
Kinetic modeling–based detection of genetic signatures that provide chemoresistance via the e2f1-p73/dnp73-mir-205 network J Vera, U Schmitz, X Lai, D Engelmann, FM Khan, O Wolkenhauer, ... Cancer research 73 (12), 3511-3524, 2013 | 67 | 2013 |
Macrophage development and activation involve coordinated intron retention in key inflammatory regulators ID Green, N Pinello, R Song, Q Lee, JM Halstead, CT Kwok, ACH Wong, ... Nucleic Acids Research 48 (12), 6513-6529, 2020 | 66 | 2020 |
The application of long-read sequencing in clinical settings JB Oehler, H Wright, Z Stark, AJ Mallett, U Schmitz Human genomics 17 (1), 73, 2023 | 65 | 2023 |
CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic AD Marshall, CG Bailey, K Champ, M Vellozzi, P O'Young, C Metierre, ... Oncogene 36 (29), 4100-4110, 2017 | 64 | 2017 |
MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology. J Vera, X Lai, U Schmitz, O Wolkenhauer Advances in experimental medicine and biology 774, 55, 2013 | 64 | 2013 |
Exosomal lncRNAs and cancer: connecting the missing links H Naderi-Meshkin, X Lai, R Amirkhah, J Vera, JEJ Rasko, U Schmitz Bioinformatics 35 (2), 352-360, 2019 | 62 | 2019 |
Challenges in defining the role of intron retention in normal biology and disease DP Vanichkina, U Schmitz, JJL Wong, JEJ Rasko Seminars in cell & developmental biology 75, 40-49, 2018 | 61 | 2018 |