| Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ... Cell 149 (3), 656-670, 2012 | 2138 | 2012 |
| FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis JH Paik, R Kollipara, G Chu, H Ji, Y Xiao, Z Ding, L Miao, Z Tothova, ... Cell 128 (2), 309-323, 2007 | 1216 | 2007 |
| Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice M Jaskelioff, FL Muller, JH Paik, E Thomas, S Jiang, AC Adams, E Sahin, ... Nature 469 (7328), 102-106, 2011 | 1064 | 2011 |
| Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH J Yun, E Mullarky, C Lu, KN Bosch, A Kavalier, K Rivera, J Roper, IIC Chio, ... Science 350 (6266), 1391-1396, 2015 | 961 | 2015 |
| PI3 kinase signals BCR-dependent mature B cell survival L Srinivasan, Y Sasaki, DP Calado, B Zhang, JH Paik, RA DePinho, ... Cell 139 (3), 573-586, 2009 | 796 | 2009 |
| Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes N Hariharan, Y Maejima, J Nakae, J Paik, RA DePinho, J Sadoshima Circulation research 107 (12), 1470-1482, 2010 | 722 | 2010 |
| Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy G Milan, V Romanello, F Pescatore, A Armani, JH Paik, L Frasson, ... Nature communications 6 (1), 6670, 2015 | 713 | 2015 |
| Lysophospholipids--receptor revelations T Hla, MJ Lee, N Ancellin, JH Paik, MJ Kluk Science 294 (5548), 1875-1878, 2001 | 666 | 2001 |
| Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells W Ouyang, O Beckett, Q Ma, J Paik, RA DePinho, MO Li Nature immunology 11 (7), 618-627, 2010 | 553 | 2010 |
| Comparative oncogenomics identifies NEDD9 as a melanoma metastasis gene M Kim, JD Gans, C Nogueira, A Wang, JH Paik, B Feng, C Brennan, ... Cell 125 (7), 1269-1281, 2006 | 507 | 2006 |
| FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis J Paik, Z Ding, R Narurkar, S Ramkissoon, F Muller, WS Kamoun, ... Cell stem cell 5 (5), 540-553, 2009 | 499 | 2009 |
| Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability T Sanchez, T Estrada-Hernandez, JH Paik, MT Wu, K Venkataraman, ... Journal of Biological Chemistry 278 (47), 47281-47290, 2003 | 496 | 2003 |
| Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis MJ Lee, S Thangada, JH Paik, GP Sapkota, N Ancellin, SS Chae, M Wu, ... Molecular cell 8 (3), 693-704, 2001 | 387 | 2001 |
| IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology M Pellegrini, T Calzascia, JG Toe, SP Preston, AE Lin, AR Elford, ... Cell 144 (4), 601-613, 2011 | 384 | 2011 |
| FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress A Sengupta, JD Molkentin, JH Paik, RA DePinho, KE Yutzey Journal of Biological Chemistry 286 (9), 7468-7478, 2011 | 361 | 2011 |
| Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of αvβ3-and β1-containing integrins JH Paik, S Chae, MJ Lee, S Thangada, T Hla Journal of Biological Chemistry 276 (15), 11830-11837, 2001 | 356 | 2001 |
| FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts MT Rached, A Kode, L Xu, Y Yoshikawa, JH Paik, RA DePinho, ... Cell metabolism 11 (2), 147-160, 2010 | 349 | 2010 |
| Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization JH Paik, A Skoura, SS Chae, AE Cowan, DK Han, RL Proia, T Hla Genes & development 18 (19), 2392-2403, 2004 | 347 | 2004 |
| Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells Y Harada, Y Harada, C Elly, G Ying, JH Paik, RA DePinho, YC Liu Journal of experimental medicine 207 (7), 1381-1391, 2010 | 323 | 2010 |
| FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice E Ambrogini, M Almeida, M Martin-Millan, JH Paik, RA DePinho, L Han, ... Cell metabolism 11 (2), 136-146, 2010 | 320 | 2010 |
Ronald A. DePinhoMD AndersonVerified email at mdanderson.org